PD-L1 expression, EGFR and KRAS mutations and survival among stage III unresected non-small cell lung cancer patients: a Danish cohort study

Autor: Deirdre Cronin-Fenton, Tapashi Dalvi, Naimisha Movva, Lars Pedersen, Hanh Hansen, Jon Fryzek, Elizabeth Hedgeman, Anders Mellemgaard, Torben R. Rasmussen, Norah Shire, Stephen Hamilton-Dutoit, Mette Nørgaard

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract Programmed cell death receptor ligand-1 (PD-L1) expression, KRAS (KRASm) and EGFR (EGFRm) mutations may influence non-small cell lung cancer (NSCLC) prognosis. We aimed to evaluate PD-L1 expression, KRASm, and EGFRm and survival among stage

Externí odkaz: https://doaj.org/article/b4c1a9ab9ce54222a8cc1b0d41e549b9

Programmed cell death ligand-1 expression and survival in a cohort of patients with non-small cell lung cancer receiving first-line through third-line therapy in Denmark

Autor: Mette Nørgaard, Torben Riis Rasmussen, Norah J. Shire, Hanh Hansen, Anders Mellemgaard, Anita Midha, Jill Walker, Elizabeth Hedgeman, Lars Pedersen, Tapashi Dalvi, Deirdre Cronin-Fenton, Stephen Hamilton-Dutoit, J. Rigas, Anne-Marie Boothman, Jon P. Fryzek

Publikováno v: Hedgeman, E, Nørgaard, M, Dalvi, T, Pedersen, L, Hansen, H P, Walker, J, Midha, A, Shire, N, Boothman, A-M, Fryzek, J P, Rigas, J, Mellemgaard, A, Rasmussen, T R, Hamilton-Dutoit, S & Cronin-Fenton, D 2021, ' Programmed cell death ligand-1 expression and survival in a cohort of patients with non-small cell lung cancer receiving first-line through third-line therapy in Denmark ', Cancer epidemiology, vol. 73, pp. 101976 . https://doi.org/10.1016/j.canep.2021.101976
Hedgeman, E, Nørgaard, M, Dalvi, T, Pedersen, L, Hansen, H P, Walker, J, Midha, A, Shire, N, Boothman, A M, Fryzek, J P, Rigas, J, Mellemgaard, A, Rasmussen, T R, Hamilton-Dutoit, S & Cronin-Fenton, D 2021, ' Programmed cell death ligand-1 expression and survival in a cohort of patients with non-small cell lung cancer receiving first-line through third-line therapy in Denmark ', Cancer epidemiology, vol. 73, 101976 . https://doi.org/10.1016/j.canep.2021.101976

BACKGROUND: PD-L1 expression on tumor cells (TCs) or immune cells (ICs) may be used as a prognostic marker for survival in patients with NSCLC. We characterized PD-L1 expression on TCs or ICs in a patient cohort with NSCLC to determine associations b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46578e6da5a61a4e3e492aa29027f4dc
https://pure.au.dk/portal/da/publications/programmed-cell-death-ligand1-expression-and-survival-in-a-cohort-of-patients-with-nonsmall-cell-lung-cancer-receiving-firstline-through-thirdline-therapy-in-denmark(d9615987-9773-43dc-9b60-de7ac1e0059e).html

Programmed cell death receptor ligand 1 (PD-L1) expression: Epidermal growth factor receptor (EGFR) and Kirsten RAS (KRAS) mutations in second-line therapy (2L) non-small cell lung cancer (NSCLC) patients—A Danish cohort study

Autor: Norah J. Shire, Tapashi Dalvi, J. Rigas, Jon P. Fryzek, Lars Pedersen, Jill Walker, Stephen Hamilton-Dutoit, Deirdre Cronin-Fenton, Elizabeth Hedgeman, David Lawrence, Anders Mellemgaard, Hanh Hansen, Henrik Toft Sørensen, Mette Nørgaard, Torben Riis Rasmussen, Danielle Potter

Publikováno v: Journal of Clinical Oncology. 35:e20523-e20523

e20523 Background: In NSCLC patients who received 2L therapy, we examined the association of PD-L1 expression, mutations in KRAS and EGFR and survival. Methods: 2L NSCLC patients diagnosed during 2001-2012 and with sufficient archival tumour tissue w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a9f52c5dd42cb0b8196f0bb58faf64f
https://doi.org/10.1200/jco.2017.35.15_suppl.e20523

Political Self-Sacrifice : Agency, Body and Emotion in International Relations

Autor: K. M. Fierke

Over the last decade the increasing phenomenon of suicide terrorism has raised questions about how it might be rational for individuals to engage in such acts. This book examines a range of different forms of political self-sacrifice, including hunge