Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hangya Peng"'
Autor:
Jie Zhang, Luming Wu, Tingwei Su, Haoyu Liu, Lei Jiang, Yiran Jiang, Zhiyuan Wu, Lu Chen, Haorong Li, Jie Zheng, Yingkai Sun, Hangya Peng, Rulai Han, Guang Ning, Lei Ye, Weiqing Wang
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundAdrenocortical carcinoma (ACC) is an aggressive endocrine malignancy with limited therapeutic options. Treating advanced ACC with mitotane, the cornerstone therapy, remains challenging, thus underscoring the significance to predict mitotane
Externí odkaz:
https://doaj.org/article/7775bf548f804819ac7a89b770f238bb
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundN6-methyladenosine (m6A) modification is a critical epigenetic modification in eukaryotes and involves several biological processes and occurrences of diseases. However, the roles and regulatory mechanisms of m6A regulators in osteoporosis
Externí odkaz:
https://doaj.org/article/81ccbe7846ac4ef4bcca573b822da959
Autor:
Jiashuang Fan, Jianli Zhou, Zhuan Qu, Hangya Peng, Shuhui Meng, Yaping Peng, Tengyan Liu, Qiu Luo, Lifen Dai
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Osteoporosis (OP) is a serious and common bone metabolic disease with bone mass loss and bone microarchitectural deterioration. The OSTEOWONDER capsule is clinically used to treat OP. However, the potential regulatory mechanism of the OST
Externí odkaz:
https://doaj.org/article/7b736cc992464e539b387dac3aea8ebb
Autor:
Hangya Peng, Panwei Mu, Haicheng Li, Shuo Lin, Chuwen Lin, Keyi Lin, Kunying Liu, Wen Zeng, Longyi Zeng
Publikováno v:
Journal of Diabetes Research, Vol 2021 (2021)
Insulin treatment was confirmed to reduce insulin resistance, but the underlying mechanism remains unknown. Caveolin-1 (Cav-1) is a functional protein of the membrane lipid rafts, known as caveolae, and is widely expressed in mammalian adipose tissue
Externí odkaz:
https://doaj.org/article/fc3e57f7dec8473db23ae4c643831fe0
Autor:
Jiashuang Fan, Jianli Zhou, Zhuan Qu, Hangya Peng, Shuhui Meng, Yaping Peng, Tengyan Liu, Qiu Luo, Lifen Dai
Publikováno v:
Frontiers in genetics. 13
Background: Osteoporosis (OP) is a serious and common bone metabolic disease with bone mass loss and bone microarchitectural deterioration. The OSTEOWONDER capsule is clinically used to treat OP. However, the potential regulatory mechanism of the OST
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380a7bd1da65718f01ec40a3e29286e4
https://pubmed.ncbi.nlm.nih.gov/35295951
https://pubmed.ncbi.nlm.nih.gov/35295951
Autor:
Haicheng Li, Keyi Lin, Rili Gao, Longyi Zeng, Hangya Peng, Kunying Liu, Jianping Weng, Shuo Lin, Yan Jiang, Wen Zeng, Haixia Xu, Chuwen Lin, Jiansong Tang, Hongyun Lu
Publikováno v:
Cellular Signalling. 47:65-78
Lipotoxicity leads to insulin secretion deficiency, which is among the important causes for the onset of type 2 diabetes mellitus. Thus, the restoration of β-cell mass and preservation of its endocrine function are long-sought goals in diabetes rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d7418e0d99c0d4ca5ba344883c258c
https://doi.org/10.1016/j.cellsig.2018.03.013
https://doi.org/10.1016/j.cellsig.2018.03.013
Autor:
Shuo Lin, Hangya Peng, Jiansong Tang, Longyi Zeng, Chuwen Lin, Yan Jiang, Wen Zeng, Kunying Liu, Keyi Lin
Publikováno v:
Diabetes. 67
Lipotoxicity induced intracellular lipid accumulation in pancreatic β cells, one of the strongest predictors for T2DM. The objective of this study is to explore the role of Cav-1 in intracellular lipid accumulation of β cells under lipotoxicity con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ae3baa4d4523e2489908189e5d49d63
https://doi.org/10.2337/db18-2141-p
https://doi.org/10.2337/db18-2141-p
Autor:
Rili Gao, Haixia Xu, Longyi Zeng, Shuo Lin, Haicheng Li, Chuwen Lin, Wen Zeng, Kunying Liu, Yan Jiang, Keyi Lin, Jiansong Tang, Hongyun Lu, Hangya Peng
Publikováno v:
Diabetes. 67
The regeneration of β-cell mass and preservation of its endocrine function under lipotoxicity are long-sought goals in diabetes research. Membrane protein caveolin-1 (Cav-1) is related to β-cell apoptosis and insulin secretion, however, the underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a04f49b0a9f4747c425a25e6c2c0d6d
https://doi.org/10.2337/db18-84-or
https://doi.org/10.2337/db18-84-or
Publikováno v:
Diabetes. 67
Insulin treatment improves insulin sensitivity, but the underlying mechanism remains unknown. Caveolin-1(Cav-1) konckout mice present insulin resistance.Our aim is to investigate the effect of Cav-1 depletion on insulin sensitivity and PI3K/AKT activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa78f199ccbc77f5887a7643e7b29276
https://doi.org/10.2337/db18-2423-pub
https://doi.org/10.2337/db18-2423-pub
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 64(1)
Our study aims to access the influence of caveolin1 (CAV1) on β cell expression profiles. We knocked down the expression of CAV1 in both NIT-1 cells and islets isolated from C57BL/6J mice using an RNA interference technique, which was realized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55875a4866fb9a3fa038d4bd4fd832ef
https://pubmed.ncbi.nlm.nih.gov/29412792
https://pubmed.ncbi.nlm.nih.gov/29412792