Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hangdi Wu"'
Autor:
Chen Cheng, Gang Wang, Yuqing Zhu, Hangdi Wu, Li Zhang, Zhihong Liu, Yuanhua Huang, Jin Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Disease modeling with isogenic Induced Pluripotent Stem Cell (iPSC)-differentiated organoids serves as a powerful technique for studying disease mechanisms. Multiplexed coculture is crucial to mitigate batch effects when studying the genetic
Externí odkaz:
https://doaj.org/article/a20c3cfa82ff4e23adc60a3e5a6e7284
Autor:
Gang Wang, Hangdi Wu, Xiuwen Zhai, Li Zhang, Changming Zhang, Chen Cheng, Xiaodong Xu, Erzhi Gao, Xushen Xiong, Jin Zhang, Zhihong Liu
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Wilms tumor‐1(WT1) is a crucial transcription factor that regulates podocyte development. However, the epigenomic mechanism underlying the function of WT1 during podocyte development has yet to be fully elucidated. Here, single‐cell chro
Externí odkaz:
https://doaj.org/article/c27d86fd5254495eafc3a6bb5ecd4b4b
Autor:
Chen Cheng, Gang Wang, Yuqing Zhu, Hangdi Wu, Li Zhang, Zhihong Liu, Yuanhua Huang, Jin Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7eaff26dc81e4752b2e0dae6e4d25713
Publikováno v:
Stem Cell Research, Vol 58, Iss , Pp 102628- (2022)
Alport syndrome is an inherited chronic kidney disease with genetic heterogeneity. There are three modes of inheritance: X-linked dominant inheritance, autosomal recessive inheritance, and autosomal dominant inheritance. Autosomal recessive inheritan
Externí odkaz:
https://doaj.org/article/651a4c11080346faa82497312b62558a
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102538- (2021)
Dent disease (DD) is a rare X-linked proximal tubulopathy associated with low molecular weight proteinuria (LMWP), hypercalciuria, nephrolithiasis and phosphoruria, which may progress to chronic kidney disease (CKD). About 60% of cases are caused by
Externí odkaz:
https://doaj.org/article/dad32f2efd014b4faff272a255328d40
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102557- (2021)
Alport syndrome is the second most common genetic renal disease which caused by mutations in COL4A3/COL4A4/COL4A5, according to different modes of inheritance. Recently, we identified a novel homozygous mutation in COL4A3 gene in a patient with Alpor
Externí odkaz:
https://doaj.org/article/1be0b88354b347a0a76cab3b59f62dd1
Autor:
Yuqing Zhu, Li Zhang, Gang Wang, Jing Zhao, Xiaolin Hou, Hangdi Wu, Yuming Xu, Jianhua Mao, Zhihong Liu, Jin Zhang
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102475- (2021)
PBMCs were collected from a patient with a novel GLA gene mutation (c.140G > A) which contributed to Fabry disease. Subsequently, an induced pluripotent stem cell (iPSC) line was derived using an episomal reprogramming method that transfer the reprog
Externí odkaz:
https://doaj.org/article/9b626493c639444f9fb2e39e68bda3ef
Autor:
Hangdi Wu, Gang Wang, Erzhi Gao, Jing Zhao, Li Zhang, Lang Chen, Yuqing Zhu, Jin Zhang, Zhihong Liu
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102293- (2021)
Focal Segmental Glomerular Sclerosis (FSGS) is a glomerular disease which can be classified into primary, secondary, genetic, and unknown forms. WT1 mutation has been shown to be associated with this disorder. Recently, we identified a mutation in th
Externí odkaz:
https://doaj.org/article/3057103d8a434158a85f72afbde9cb6d
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102023- (2020)
The clinical manifestations of Alport syndrome may vary depending on the involved organs such as the kidneys, cochlea and eyes. The pathogenic genes involved are those encoding different chains of type IV collagen. We collected PBMCs of a patient wit
Externí odkaz:
https://doaj.org/article/3d6821ce06684d68bac2e4c64327ed11
Publikováno v:
Stem Cell Research, Vol 56, Iss, Pp 102538-(2021)
Dent disease (DD) is a rare X-linked proximal tubulopathy associated with low molecular weight proteinuria (LMWP), hypercalciuria, nephrolithiasis and phosphoruria, which may progress to chronic kidney disease (CKD). About 60% of cases are caused by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5aea24f0808980315d8bea6dfbfef5f
http://www.sciencedirect.com/science/article/pii/S1873506121003858
http://www.sciencedirect.com/science/article/pii/S1873506121003858