Zobrazeno 1 - 10
of 142
pro vyhledávání: '"HangYuan Guo"'
Autor:
Juntao Yang, Tingting Lv, Jiedong Zhou, Hui Lin, Bingjie Zhao, Haifei Lou, Hanxuan Liu, Tao Zhang, Hangyuan Guo, Jufang Chi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundIvabradine improves cardiac function in patients with heart failure, but its effect on dilated cardiomyopathy (DCM) remains unclear. We performed a systematic review and meta-analysis to study the efficacy and potential mechanisms of ivabra
Externí odkaz:
https://doaj.org/article/7a1f7e3e58cf4f62b576e19a9174de21
Autor:
Jing Sun, Jiedong Zhou, Shimin Sun, Hui Lin, Hanlin Zhang, Zuoquan Zhong, Jufang Chi, HangYuan Guo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Doxorubicin (DOX) has a wide antitumor spectrum, but its adverse cardiotoxicity may lead to heart failure. Urotensin II (UII) is the most potent vasoconstrictor in mammals. It plays a role by activating the UII receptor (UT), the orphan G pr
Externí odkaz:
https://doaj.org/article/606007b65b3f4666a20b7f1e6532c675
Autor:
Zuoquan Zhong, Hanlin Zhang, Ting Xu, Jinjin Hao, Xing Chen, Shimin Sun, Jinjin Yang, Jing Sun, Hui Lin, Hangyuan Guo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
PurposeDiabetic heart failure (DHF) or cardiomyopathy is a common complication of diabetes; however, the underlying mechanism is not clear. In the present study, the authors searched for differentially expressed genes associated with DHF and the mole
Externí odkaz:
https://doaj.org/article/4a387fc031cf461ab172c1169f28ab2a
Autor:
Jiedong Zhou, Jingfan Weng, Xingxiao Huang, Shimin Sun, Qi Yang, Hui Lin, Jinjin Yang, Hangyuan Guo, Jufang Chi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundChronic endoplasmic reticulum stress (ERS) plays a crucial role in cardiovascular diseases. Thus, it can be considered a therapeutic target for these diseases. In this study, poly (D,L-lactic acid) (PDLLA) nanoparticle-eluting stents loaded
Externí odkaz:
https://doaj.org/article/2da9f4ee381c49d7bd886d2f27c0c559
Autor:
Jinjin Yang, Jiaoying Song, Jiedong Zhou, Hui Lin, Zhuonan Wu, Nan Liu, Wenqing Xie, Hangyuan Guo, Jufang Chi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundDietary polyphenols, polypeptides, and oligosaccharides modulate inflammation and immunity by altering the composition of gut microbiota. The polyphenols and polypeptides in Chinese rice wine have protective effects against cardiovascular d
Externí odkaz:
https://doaj.org/article/9eebbda8a62d4091a6ff4c7ccf206eb8
Autor:
Zuoquan Zhong, Shiming Sun, Jingfan Weng, Hanlin Zhang, Hui Lin, Jing Sun, Miaohong Pan, Hangyuan Guo, Jufang Chi
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
BackgroundIn recent years, the prevalence of type 2 diabetes mellitus (T2DM) has increased annually. The major complication of T2DM is cardiovascular disease (CVD). CVD is the main cause of death in T2DM patients, particularly those with comorbid acu
Externí odkaz:
https://doaj.org/article/3774a14db3894f538661482a989d4fd8
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundThe high prevalence of patent foramen ovale (PFO) in cryptogenic stroke suggested a stroke-causing role for PFO. As risk factors for recurrence of such stroke are not recognized, clinicians cannot sufficiently identify, treat, and follow-up
Externí odkaz:
https://doaj.org/article/1b69e34cf8ef4121876c5df580d659c2
Autor:
Jiedong Zhou, Hui Lin, Tingting Lv, Jinjin Hao, Hanlin Zhang, Shimin Sun, Juntao Yang, Jufang Chi, Hangyuan Guo
Publikováno v:
Cardiovascular Innovations and Applications, Vol 7, Iss 1, p 989 (2022)
Significance: Heart failure, a disease with extremely high incidence, is closely associated with inflammation and oxidative stress. The Toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) pathway plays an important role in the occurrence and
Externí odkaz:
https://doaj.org/article/1ffc7ddabb344459966027e78071d3c1
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Cardiac fibroblast (CF) activation is a hallmark feature of cardiac fibrosis in diabetic cardiomyopathy (DCM). Inhibition of the sodium-dependent glucose transporter 1 (SGLT1) attenuates cardiomyocyte apoptosis and delays the development
Externí odkaz:
https://doaj.org/article/5f1e88a7b29e4fbfa3848f3c00141482
Autor:
Na Lin, Hui Lin, Qi Yang, Wenqiang Lu, Zhenzhu Sun, Shimin Sun, Liping Meng, Jufang Chi, Hangyuan Guo
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Background: Recent studies have revealed that a novel selective sodium-glucose cotransporter 1 (SGLT1) inhibiton has shown beneficial effects in cardiovascular diseases. However, the question of whether SGLT1 inhibition influences diabetic cardiomyop
Externí odkaz:
https://doaj.org/article/871080a19fc34e1581cb5aea495a762e