Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hang Gyeong Chin"'
Autor:
Pierre-Olivier Estève, Sagnik Sen, Udayakumar S. Vishnu, Cristian Ruse, Hang Gyeong Chin, Sriharsa Pradhan
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022)
SET8 is post-translationally poly ADPribosylated by PARP1 on several lysine residues, leading to SET8 degradation via ubiquitylation and genome-wide aberrant H4K20 methylation.
Externí odkaz:
https://doaj.org/article/99363f409dd743ae9dcafbee136ff4b4
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Background Accessible chromatin landscape allows binding of transcription factors, and remodeling of promoter and enhancer elements during development. Chromatin accessibility along with integrated multiomics approaches have been used for de
Externí odkaz:
https://doaj.org/article/3b67d3bcaff44fd39095aff16c99585c
Autor:
Jennifer L. S. Willoughby, Kelly George, Mark P. Roberto, Hang Gyeong Chin, Patrick Stoiber, Hyunjin Shin, Chandra Sekhar Pedamallu, Scott E. Schaus, Kevin Fitzgerald, Jagesh Shah, Ulla Hansen
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background The oncogene LSF (encoded by TFCP2) has been proposed as a novel therapeutic target for multiple cancers. LSF overexpression in patient tumors correlates with poor prognosis in particular for both hepatocellular carcinoma and colo
Externí odkaz:
https://doaj.org/article/78196f74ff6642ea90ac3be30f035d7e
Autor:
Sarah A. Yunes, Jennifer L. S. Willoughby, Julian H. Kwan, Jessica M. Biagi, Niranjana Pokharel, Hang Gyeong Chin, Emily A. York, Kuan-Chung Su, Kelly George, Jagesh V. Shah, Andrew Emili, Scott E. Schaus, Ulla Hansen
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Factor quinolinone inhibitors (FQIs), a first-in-class set of small molecule inhibitors targeted to the transcription factor LSF (TFCP2), exhibit promising cancer chemotherapeutic properties. FQI1, the initial lead compound identified, unexpectedly i
Externí odkaz:
https://doaj.org/article/6ae848c8bada4a1bafa17d2db5c202d0
Autor:
Ian R Henderson, Angelique Deleris, William Wong, Xuehua Zhong, Hang Gyeong Chin, Gregory A Horwitz, Krystyna A Kelly, Sriharsa Pradhan, Steven E Jacobsen
Publikováno v:
PLoS Genetics, Vol 6, Iss 10, p e1001182 (2010)
Eukaryotic DNA cytosine methylation can be used to transcriptionally silence repetitive sequences, including transposons and retroviruses. This silencing is stable between cell generations as cytosine methylation is maintained epigenetically through
Externí odkaz:
https://doaj.org/article/3f19eaea17714810afcdd85c789a622c
Publikováno v:
Amino Acids. 54:529-542
Polyglutamylation is a posttranslational modification (PTM) that adds several glutamates on glutamate residues in the form of conjugated peptide chains by a family of enzymes known as polyglutamylases. Polyglutamylation is well documented in microtub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e97f8680d4dbf7d7f6449ba700c83c
https://doi.org/10.1007/s00726-022-03146-4
https://doi.org/10.1007/s00726-022-03146-4
Autor:
Hang Gyeong Chin, Udayakumar S. Vishnu, Zhiyi Sun, V. K. Chaithanya Ponnaluri, Guoqiang Zhang, Shuang-yong Xu, Touati Benoukraf, Paloma Cejas, George Spracklin, Pierre-Olivier Estève, Henry W. Long, Sriharsa Pradhan
Publikováno v:
Chromatin Accessibility ISBN: 9781071628980
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3303cb444f9829c4af1cb23e079102b
https://doi.org/10.1007/978-1-0716-2899-7_3
https://doi.org/10.1007/978-1-0716-2899-7_3
Publikováno v:
Chromatin Accessibility ISBN: 9781071628980
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687901d2c8d794240bc9e6cf2e0e13b6
https://doi.org/10.1007/978-1-0716-2899-7_16
https://doi.org/10.1007/978-1-0716-2899-7_16
Autor:
Lu Sun, Hannah Willis, Matthew R. Marunde, Vishnu U. Kumary, Matthew J. Meiners, Saarang Gopinath, Jonathan M. Burg, Bryan J. Venters, Allison Hickman, Zu-Wen Sun, Martis W. Cowles, Pierre Esteve, Hang Gyeong Chin, Chaithanya Ponnaluri, Sriharsa Pradhan, Michael-Christopher Keogh
Publikováno v:
Cancer Research. 83:4728-4728
Chromatin remodeling is mediated by ATP-dependent enzymes that play key roles regulating gene expression and genome replication/repair. Aberrant nucleosome organization from dysregulated chromatin remodeling can severely alter chromatin accessibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea34cab5bb0c8f6e2385230ae125ff9d
https://doi.org/10.1158/1538-7445.am2023-4728
https://doi.org/10.1158/1538-7445.am2023-4728
Autor:
Juan M. Vaquerizas, Maria-Elena Torres-Padilla, Thomas Jenuwein, Elias R. Ruiz-Morales, Nathalie Beaujean, Xiaoyu Liu, Vincent Brochard, Sriharsa Pradhan, Stéphanie Le Gras, Hang Gyeong Chin, André Eid, Vishnu S. Udayakumar, Diego Rodriguez-Terrones, Quirze Rovira, Chenfei Wang, Adam Burton, Shaorong Gao, Carmen Galán, Kai Kruse
Publikováno v:
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2020, 22 (7), pp.767-778. ⟨10.1038/s41556-020-0536-6⟩
Nat. Cell Biol. 22, 767-778 (2020)
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2020, 22 (7), pp.767-778. ⟨10.1038/s41556-020-0536-6⟩
Nat. Cell Biol. 22, 767-778 (2020)
Nature cell biology
Following fertilization in mammals, the gametes are reprogrammed to create a totipotent zygote, a process that involves de novo establishment of chromatin domains. A major feature occurring during preimplantation development is the dramatic remodelli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1112a9580979b47d17fd4e006fb1c81f
https://doi.org/10.1038/s41556-020-0536-6
https://doi.org/10.1038/s41556-020-0536-6