Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Handuo, Shi"'
Autor:
Natasha K. Dudek, Jesus G. Galaz-Montoya, Handuo Shi, Megan Mayer, Cristina Danita, Arianna I. Celis, Tobias Viehboeck, Gong-Her Wu, Barry Behr, Silvia Bulgheresi, Kerwyn Casey Huang, Wah Chiu, David A. Relman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Much remains to be explored regarding the diversity of uncultured, host-associated microbes. Here, we describe rectangular bacterial structures (RBSs) in the mouths of bottlenose dolphins. DNA staining revealed multiple paired bands within R
Externí odkaz:
https://doaj.org/article/cae2d35f97474e77bc9c56e749b36bf6
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5838-5846 (2022)
Filament formation by cytoskeletal proteins is critical to their involvement in myriad cellular processes. The bacterial actin homolog MreB, which is essential for cell-shape determination in many rod-shaped bacteria, has served as a model system for
Externí odkaz:
https://doaj.org/article/ced24bcd449d42f495fb58eda4ac1863
Autor:
Handuo Shi, Yan Hu, Pascal D. Odermatt, Carlos G. Gonzalez, Lichao Zhang, Joshua E. Elias, Fred Chang, Kerwyn Casey Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Bacterial cells actively change their size and shape in response to external environments. Here, Shi et al. explore how cells regulate their morphology during rapid environmental changes, showing that the characteristic dynamics of surface area-to-vo
Externí odkaz:
https://doaj.org/article/8655797fa5824bc7be32169e64b6d780
Autor:
Arianna I. Celis, Andrés Aranda-Díaz, Rebecca Culver, Katherine Xue, David Relman, Handuo Shi, Kerwyn Casey Huang
Publikováno v:
iScience, Vol 25, Iss 4, Pp 103907- (2022)
Summary: While microbial communities inhabit a wide variety of complex natural environments, in vitro culturing enables highly controlled conditions and high-throughput interrogation for generating mechanistic insights. In vitro assemblies of gut com
Externí odkaz:
https://doaj.org/article/116b1a97d51c47e4a783f84ef04e97e7
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The actin homolog MreB directs cell-wall insertion and maintains cell shape in many rod-shaped bacteria. Here, Shi et al. perform molecular dynamics simulations for MreB to extract mechanical parameters for inputs into a coarse-grained biophysical po
Externí odkaz:
https://doaj.org/article/efd723093a744b6da7132d60fc3c5c6d
Autor:
Melanie R. Silvis, Manohary Rajendram, Handuo Shi, Hendrik Osadnik, Andrew N. Gray, Spencer Cesar, Jason M. Peters, Cameron C. Hearne, Parth Kumar, Horia Todor, Kerwyn Casey Huang, Carol A. Gross
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Essential genes make up only ∼5 to 10% of the genetic complement in most organisms but occupy much of their protein synthesis and account for almost all antibiotic targets. Despite the importance of essential genes, their intractability has, until
Externí odkaz:
https://doaj.org/article/ac0ea87fcbd444e6a5571025f19f94b5
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Bacterial cells in their natural environments encounter rapid and large changes in external osmolality. For instance, enteric bacteria such as Escherichia coli experience a rapid decrease when they exit from host intestines. Changes in osmolality alt
Externí odkaz:
https://doaj.org/article/0d48fdcaa2c84739b88cbf9765162e3b
Autor:
Esha Atolia, Spencer Cesar, Heidi A. Arjes, Manohary Rajendram, Handuo Shi, Benjamin D. Knapp, Somya Khare, Andrés Aranda-Díaz, Richard E. Lenski, Kerwyn Casey Huang
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Bacterial growth under nutrient-rich and starvation conditions is intrinsically tied to the environmental history and physiological state of the population. While high-throughput technologies have enabled rapid analyses of mutant libraries,
Externí odkaz:
https://doaj.org/article/7ba8cdbef49643fca248f598ea6e92fd
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Membrane protein RodZ interacts with the actin-like protein MreB, which coordinates cell-wall insertion to maintain the typical rod-like shape of E. coli cells. Here, the authors provide evidence that RodZ modulates the biophysical properties of MreB
Externí odkaz:
https://doaj.org/article/b9d890ceabe244c0a401c4b57881a85c
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 4, p e1006683 (2019)
The actin family of cytoskeletal proteins is essential to the physiology of virtually all archaea, bacteria, and eukaryotes. While X-ray crystallography and electron microscopy have revealed structural homologies among actin-family proteins, these te
Externí odkaz:
https://doaj.org/article/9de135470a34456aa9a8bd68297d768c