Výsledky vyhledávání - "Handrian Ramoko"

Akademický článek

Optimizing chemically stable chloramphenicol in-situ gel formulations using poloxamer 407 and HPMC through full-factorial design

Autor: Insan Sunan Kurniawansyah, Taofik Rusdiana, Insi Farisa Desy Arya, Handrian Ramoko, Habibah A. Wahab

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Abstract The primary goal was to enhance the stability and bioavailability of chloramphenicol for ophthalmic use without compromising patient comfort, such as causing blurry vision. This study employed a 2-level full factorial design to optimize the

Externí odkaz: https://doaj.org/article/9e2fb62a41824c6c9bb8c0093464d893

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

In situ ophthalmic gel forming systems of poloxamer 407 and hydroxypropyl methyl cellulose mixtures for sustained ocular delivery of chloramphenicole: optimization study by factorial design

Autor: Insan Sunan Kurniawansyah, Taofik Rusdiana, Iyan Sopyan, Handrian Ramoko, Habibah A. Wahab, Anas Subarnas

Publikováno v: Heliyon, Vol 6, Iss 11, Pp e05365- (2020)

Background: Conventional drug delivery systems have some major drawbacks such as low bioavailability, short residence time and rapid precorneal drainage. An in situ gel drug delivery system provides several benefits, such as prolonged pharmacological

Externí odkaz: https://doaj.org/article/7b0d4417fde4472da15007070844aeaa

Zobrazit plný text záznamu

IN VITRO DRUG RELEASE STUDY OF CHLORAMPHENICOL IN SITU GEL WITH BASES MIXTURE OF POLOXAMER 407 AND HPMC BY OPTIMIZATION WITH FACTORIAL DESIGN

Autor: INSAN SUNAN KURNIAWANSYAH, TAOFIK RUSDIANA, HURIYATUS TSANIYAH, HANDRIAN RAMOKO, HABIBAH A. WAHAB, ANAS SUBARNAS

Publikováno v: International Journal of Applied Pharmaceutics. :116-123

Objective: The objective of this study was to find the best base mixture composition (poloxamer 407 and HPMC) of chloramphenicol in situ gel formula based on in vitro property (Cumulative amount of drug release). Methods: The in vitro diffusion of ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0d5e9fec8f9345f8256e8347278ff6c
https://doi.org/10.22159/ijap.2021.v13s4.43829

Zobrazit plný text záznamu

In situ ophthalmic gel forming systems of poloxamer 407 and hydroxypropyl methyl cellulose mixtures for sustained ocular delivery of chloramphenicole: optimization study by factorial design

Autor: Iyan Sopyan, Habibah A. Wahab, Handrian Ramoko, Insan Sunan Kurniawansyah, Taofik Rusdiana, Anas Subarnas

Publikováno v: Heliyon, Vol 6, Iss 11, Pp e05365-(2020)
Heliyon

Background Conventional drug delivery systems have some major drawbacks such as low bioavailability, short residence time and rapid precorneal drainage. An in situ gel drug delivery system provides several benefits, such as prolonged pharmacological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde63c68214f95837b3106995e0561f6
http://www.sciencedirect.com/science/article/pii/S2405844020322088

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání