Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Hande Özdinler"'
Autor:
Mukesh Gautam, Barış Genç, Benjamin Helmold, Angela Ahrens, Janis Kuka, Marina Makrecka-Kuka, Aksu Günay, Nuran Koçak, Izaak R. Aguilar-Wickings, Dennis Keefe, Guozhu Zheng, Suchitra Swaminathan, Martin Redmon, Hatim A. Zariwala, P. Hande Özdinler
Publikováno v:
Neurobiology of Disease, Vol 178, Iss , Pp 106022- (2023)
Mitochondrial defects are one of the common underlying causes of neuronal vulnerability in neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS), and TDP-43 pathology is the most commonly observed proteinopathy. Disrupted inner mito
Externí odkaz:
https://doaj.org/article/500a9a36e006467bbaa75e89a1dedef4
Autor:
Javier H. Jara, Mukesh Gautam, Nuran Kocak, Edward F. Xie, Qinwen Mao, Eileen H. Bigio, P. Hande Özdinler
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background The involvement of non-neuronal cells and the cells of innate immunity has been attributed to the initiation and progression of ALS. TDP-43 pathology is observed in a broad spectrum of ALS cases and is one of the most commonly sha
Externí odkaz:
https://doaj.org/article/4fb169a5f82540d09bc348b70cdffa81
Autor:
Barış Genç, Mukesh Gautam, Öge Gözütok, Ina Dervishi, Santana Sanchez, Gashaw M. Goshu, Nuran Koçak, Edward Xie, Richard B. Silverman, P. Hande Özdinler
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 2, Pp n/a-n/a (2021)
Abstract Background Upper motor neurons (UMNs) are a key component of motor neuron circuitry. Their degeneration is a hallmark for diseases, such as hereditary spastic paraplegia (HSP), primary lateral sclerosis (PLS), and amyotrophic lateral scleros
Externí odkaz:
https://doaj.org/article/5370d3704c9349de99b927f4e9b91ea3
Autor:
Javier H. Jara, Barış Genç, Macdonell J. Stanford, Peter Pytel, Raymond P. Roos, Sandra Weintraub, M. Marsel Mesulam, Eileen H. Bigio, Richard J. Miller, P. Hande Özdinler
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-20 (2017)
Abstract Background Recent evidence indicates the importance of innate immunity and neuroinflammation with microgliosis in amyotrophic lateral sclerosis (ALS) pathology. The MCP1 (monocyte chemoattractant protein-1) and CCR2 (CC chemokine receptor 2)
Externí odkaz:
https://doaj.org/article/97c3d0e9ad8a4982a0dcf8b1afc51f08
Autor:
Mohamed F. Elmansy, Cory T. Reidl, Mizzanoor Rahaman, P. Hande Özdinler, Richard B. Silverman
Publikováno v:
Medicinal Research Reviews.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::131824f96916296680bc06ca50e24b2b
https://doi.org/10.1002/med.21974
https://doi.org/10.1002/med.21974
Autor:
Barış Genç, Boram Nho, Hana Seung, Benjamin Helmold, Huiwon Park, Öge Gözütok, Seunghyun Kim, Jinil Park, Sanghyun Ye, Haneul Lee, Nayeon Lee, Seung-Shin Yu, Sunyoung Kim, Junghun Lee, Hande Özdinler
Publikováno v:
Gene Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dbf3261a1d263fdece95e52c2997492
https://doi.org/10.1038/s41434-023-00383-4
https://doi.org/10.1038/s41434-023-00383-4
Autor:
Mukesh Gautam, Barış Genç, Benjamin Helmold, Angela Ahrens, Janis Kuka, Marina Makrecka-Kuka, Aksu Günay, Nuran Koçak, Izaak R. Aguilar-Wickings, Dennis Keefe, Guozhu Zheng, Suchitra Swaminathan, Martin Redmon, Hatim A. Zariwala, P. Hande Özdinler
Mitochondrial defects are one of the common underlying causes of neuronal vulnerability in motor neuron diseases, such as amyotrophic lateral sclerosis (ALS), and TDP-43 pathology is the most common proteinopathy in ALS. Disrupted inner mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3353495380527735ee054cd2e13b0ce6
https://doi.org/10.1101/2022.10.04.510854
https://doi.org/10.1101/2022.10.04.510854
Autor:
P. Hande Özdinler
Publikováno v:
FEBS J
In neurodegenerative diseases a select set of neuron population displays early vulnerability and undergo progressive degeneration. The heterogeneity of the cerebral cortex and the heterogeneity of patient populations diagnosed with the same disease o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2061f7a174040881a4a5979b50b97244
https://doi.org/10.1111/febs.15529
https://doi.org/10.1111/febs.15529
Publikováno v:
Neurobiology of Disease, Vol 47, Iss 2, Pp 174-183 (2012)
Corticospinal motor neurons (CSMN) are the cortical component of motor neuron circuitry, which controls voluntary movement and degenerates in diseases such as amyotrophic lateral sclerosis, primary lateral sclerosis and hereditary spastic paraplegia.
Externí odkaz:
https://doaj.org/article/8052c433044644a094d3b55007875f6b
Autor:
Barış Genç, Amiko Krisa Bunag Lagrimas, Pınar Kuru, Robert Hess, Michael William Tu, Daniela Maria Menichella, Richard J Miller, Amy S Paller, P Hande Özdinler
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132815 (2015)
Visualization of peripheral nervous system axons and cell bodies is important to understand their development, target recognition, and integration into complex circuitries. Numerous studies have used protein gene product (PGP) 9.5 [a.k.a. ubiquitin c
Externí odkaz:
https://doaj.org/article/e6c7c98634ad4e688648684127f6c9df