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Germline competency of human embryonic stem cells depends on eomesodermin

Autor: Chen, Di, Liu, Wanlu, Lukianchikov, Anastasia, Hancock, Grace V, Zimmerman, Jill, Lowe, Matthew G, Kim, Rachel, Galic, Zoran, Irie, Naoko, Surani, M Azim, Jacobsen, Steven E, Clark, Amander T

Publikováno v: Biology of reproduction, vol 97, iss 6

In humans, germline competency and the specification of primordial germ cells (PGCs) are thought to occur in a restricted developmental window during early embryogenesis. Despite the importance of specifying the appropriate number of PGCs for human r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::4193294eedf4ebf1c80e044b16f8de92
https://escholarship.org/uc/item/3wh4z770

Germline competency of human embryonic stem cells depends on eomesodermin.

Autor: Chen D; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California, USA., Liu W; Molecular Biology Institute, University of California, Los Angeles, California, USA., Lukianchikov A; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California, USA., Hancock GV; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California, USA.; Molecular Biology Institute, University of California, Los Angeles, California, USA., Zimmerman J; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California, USA., Lowe MG; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California, USA.; Molecular Biology Institute, University of California, Los Angeles, California, USA., Kim R; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, California, USA., Galic Z; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, California, USA.; Department of Medicine, University of California, Los Angeles, California, USA., Irie N; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK., Surani MA; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK., Jacobsen SE; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California, USA.; Molecular Biology Institute, University of California, Los Angeles, California, USA.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, California, USA.; Department of Biological Chemistry, University of California, Los Angeles, California, USA.; Howard Hughes Medical Institute, University of California, Los Angeles, California, USA., Clark AT; Department of Molecular Cell and Developmental Biology, University of California, Los Angeles, California, USA.; Molecular Biology Institute, University of California, Los Angeles, California, USA.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, California, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, California, USA.

Publikováno v: Biology of reproduction [Biol Reprod] 2017 Jan 01; Vol. 97 (6), pp. 850-861.