Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Hanchuan Peng"'
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113871- (2024)
Summary: We examined the distribution of pre-synaptic contacts in axons of mouse neurons and constructed whole-brain single-cell neuronal networks using an extensive dataset of 1,891 fully reconstructed neurons. We found that bouton locations were no
Externí odkaz:
https://doaj.org/article/617e2d11a23f471291ef08a7cdd551d7
Autor:
Andy Wai Kan Yeung, Ali Torkamani, Atul J. Butte, Benjamin S. Glicksberg, Björn Schuller, Blanca Rodriguez, Daniel S. W. Ting, David Bates, Eva Schaden, Hanchuan Peng, Harald Willschke, Jeroen van der Laak, Josip Car, Kazem Rahimi, Leo Anthony Celi, Maciej Banach, Maria Kletecka-Pulker, Oliver Kimberger, Roland Eils, Sheikh Mohammed Shariful Islam, Stephen T. Wong, Tien Yin Wong, Wei Gao, Søren Brunak, Atanas G. Atanasov
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
Digital health technologies have been in use for many years in a wide spectrum of healthcare scenarios. This narrative review outlines the current use and the future strategies and significance of digital health technologies in modern healthcare appl
Externí odkaz:
https://doaj.org/article/bf8036d28dfa46fc9da203755a4a38ec
Autor:
Michael Hawrylycz, Maryann E Martone, Giorgio A Ascoli, Jan G Bjaalie, Hong-Wei Dong, Satrajit S Ghosh, Jesse Gillis, Ronna Hertzano, David R Haynor, Patrick R Hof, Yongsoo Kim, Ed Lein, Yufeng Liu, Jeremy A Miller, Partha P Mitra, Eran Mukamel, Lydia Ng, David Osumi-Sutherland, Hanchuan Peng, Patrick L Ray, Raymond Sanchez, Aviv Regev, Alex Ropelewski, Richard H Scheuermann, Shawn Zheng Kai Tan, Carol L Thompson, Timothy Tickle, Hagen Tilgner, Merina Varghese, Brock Wester, Owen White, Hongkui Zeng, Brian Aevermann, David Allemang, Seth Ament, Thomas L Athey, Cody Baker, Katherine S Baker, Pamela M Baker, Anita Bandrowski, Samik Banerjee, Prajal Bishwakarma, Ambrose Carr, Min Chen, Roni Choudhury, Jonah Cool, Heather Creasy, Florence D'Orazi, Kylee Degatano, Benjamin Dichter, Song-Lin Ding, Tim Dolbeare, Joseph R Ecker, Rongxin Fang, Jean-Christophe Fillion-Robin, Timothy P Fliss, James Gee, Tom Gillespie, Nathan Gouwens, Guo-Qiang Zhang, Yaroslav O Halchenko, Nomi L Harris, Brian R Herb, Houri Hintiryan, Gregory Hood, Sam Horvath, Bingxing Huo, Dorota Jarecka, Shengdian Jiang, Farzaneh Khajouei, Elizabeth A Kiernan, Huseyin Kir, Lauren Kruse, Changkyu Lee, Boudewijn Lelieveldt, Yang Li, Hanqing Liu, Lijuan Liu, Anup Markuhar, James Mathews, Kaylee L Mathews, Chris Mezias, Michael I Miller, Tyler Mollenkopf, Shoaib Mufti, Christopher J Mungall, Joshua Orvis, Maja A Puchades, Lei Qu, Joseph P Receveur, Bing Ren, Nathan Sjoquist, Brian Staats, Daniel Tward, Cindy T J van Velthoven, Quanxin Wang, Fangming Xie, Hua Xu, Zizhen Yao, Zhixi Yun, Yun Renee Zhang, W Jim Zheng, Brian Zingg
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002133 (2023)
Characterizing cellular diversity at different levels of biological organization and across data modalities is a prerequisite to understanding the function of cell types in the brain. Classification of neurons is also essential to manipulate cell typ
Externí odkaz:
https://doaj.org/article/5683e726eb424a3187544a44691a1d0f
Publikováno v:
Frontiers in Neuroinformatics, Vol 17 (2023)
BackgroundNeuron morphology analysis is an essential component of neuron cell-type definition. Morphology reconstruction represents a bottleneck in high-throughput morphology analysis workflow, and erroneous extra reconstruction owing to noise and en
Externí odkaz:
https://doaj.org/article/f889d7bd2f18477ca984fda582b355dc
Autor:
Shuxia Guo, Jie Xue, Jian Liu, Xiangqiao Ye, Yichen Guo, Di Liu, Xuan Zhao, Feng Xiong, Xiaofeng Han, Hanchuan Peng
Publikováno v:
Brain Informatics, Vol 9, Iss 1, Pp 1-14 (2022)
Abstract A deep understanding of the neuronal connectivity and networks with detailed cell typing across brain regions is necessary to unravel the mechanisms behind the emotional and memorial functions as well as to find the treatment of brain impair
Externí odkaz:
https://doaj.org/article/af56760039ea4987ab72e28e8371b188
Autor:
Zhouzhou Zhang, Xiao Yao, Xinxin Yin, Zhangcan Ding, Tianyi Huang, Yan Huo, Runan Ji, Hanchuan Peng, Zengcai V. Guo
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
Whole-brain imaging has become an increasingly important approach to investigate neural structures, such as somata distribution, dendritic morphology, and axonal projection patterns. Different structures require whole-brain imaging at different resol
Externí odkaz:
https://doaj.org/article/158a3aa13b134bc294f89ba3ecb1e027
Autor:
Yimin Wang, Qi Li, Lijuan Liu, Zhi Zhou, Zongcai Ruan, Lingsheng Kong, Yaoyao Li, Yun Wang, Ning Zhong, Renjie Chai, Xiangfeng Luo, Yike Guo, Michael Hawrylycz, Qingming Luo, Zhongze Gu, Wei Xie, Hongkui Zeng, Hanchuan Peng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Reconstructing the full shape of neurons is a major informatics challenge as it requires handling huge whole-brain imaging datasets. Here the authors present an open-source virtual reality annotation system for precise and efficient data production o
Externí odkaz:
https://doaj.org/article/ce9a4d0ad20b4d9db384d05fc51ef648
Publikováno v:
Brain Informatics, Vol 5, Iss 2, Pp 1-9 (2018)
Abstract Reconstructing three-dimensional (3D) morphology of neurons is essential for understanding brain structures and functions. Over the past decades, a number of neuron tracing tools including manual, semiautomatic, and fully automatic approache
Externí odkaz:
https://doaj.org/article/52405e0942b14cf68440d09baedc84b4
Autor:
Hanbo Chen, Daniel Maxim Iascone, Nuno Maçarico da Costa, Ed S. Lein, Tianming Liu, Hanchuan Peng
Publikováno v:
Brain Informatics, Vol 4, Iss 3, Pp 183-186 (2017)
Abstract Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching
Externí odkaz:
https://doaj.org/article/24651c7f86574d66a73a69cdcac0f3b6
Autor:
Arnim Jenett, Gerald M. Rubin, Teri-T.B. Ngo, David Shepherd, Christine Murphy, Heather Dionne, Barret D. Pfeiffer, Amanda Cavallaro, Donald Hall, Jennifer Jeter, Nirmala Iyer, Dona Fetter, Joanna H. Hausenfluck, Hanchuan Peng, Eric T. Trautman, Robert R. Svirskas, Eugene W. Myers, Zbigniew R. Iwinski, Yoshinori Aso, Gina M. DePasquale, Adrianne Enos, Phuson Hulamm, Shing Chun Benny Lam, Hsing-Hsi Li, Todd R. Laverty, Fuhui Long, Lei Qu, Sean D. Murphy, Konrad Rokicki, Todd Safford, Kshiti Shaw, Julie H. Simpson, Allison Sowell, Susana Tae, Yang Yu, Christopher T. Zugates
Publikováno v:
Cell Reports, Vol 2, Iss 4, Pp 991-1001 (2012)
We established a collection of 7,000 transgenic lines of Drosophila melanogaster. Expression of GAL4 in each line is controlled by a different, defined fragment of genomic DNA that serves as a transcriptional enhancer. We used confocal microscopy of
Externí odkaz:
https://doaj.org/article/dbd0a912927e488f9befcefdee9e79e0