Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hanane Akhdar"'
Autor:
Lama Jaffal, Hanane Akhdar, Hawraa Joumaa, Mariam Ibrahim, Zahraa Chhouri, Alexandre Assi, Charles Helou, Hane Lee, Go Hun Seo, Wissam H. Joumaa, Said El Shamieh
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The purpose of this study was to expand the mutation spectrum by searching the causative mutations in nine Lebanese families with Usher syndrome (USH) using whole-exome sequencing. The pathogenicity of candidate mutations was first evaluated accordin
Externí odkaz:
https://doaj.org/article/7ad1c41ee1c94d069ba33e1183875909
Autor:
Hanane Akhdar, Said El Shamieh, Orlando Musso, Romain Désert, Wissam Joumaa, Dominique Guyader, Caroline Aninat, Anne Corlu, Fabrice Morel
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167543 (2016)
Glutathione S-transferases (GSTs) detoxify toxic molecules by conjugation with reduced glutathione and regulate cell signaling. Single nucleotide polymorphisms (SNPs) of GST genes have been suggested to affect GST functions and thus to increase the r
Externí odkaz:
https://doaj.org/article/06bf2c0e15e94a8f97aa2dba313e1a19
Publikováno v:
International Journal of Environment, Agriculture and Biotechnology. 2:2569-2572
Autor:
Wassim Rammal, Hassan Khachfe, Véronique Bach, Wiam Ramadan, Marwan Koubaissi, Wissam H. Joumaa, Lina Sabra, Walaa Darwich, Hanane Akhdar
Publikováno v:
The FASEB Journal. 27
Publikováno v:
Topics on Drug Metabolism
Over the last decades, several studies have demonstrated that cancer cells have a unique metabolism compared to normal cells (Herling et al., 2011). Metabolic changes occurring in cancer cells are considered to be fundamental for the transformation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93d49140bf75c62d8c943a616476e12f
http://www.intechopen.com/articles/show/title/anticancer-drug-metabolism-chemotherapy-resistance-and-new-therapeutic-approaches
http://www.intechopen.com/articles/show/title/anticancer-drug-metabolism-chemotherapy-resistance-and-new-therapeutic-approaches
Autor:
Aida Ibreik, Mouhammed Ezzeddine, Dana Zeyneddine, Yolla Makhour, Wiam Ramadan, Hanane Akhdar, Fatima Jebai, Wissam H. Joumaa
Publikováno v:
The FASEB Journal. 25
Publikováno v:
European journal of cancer (Oxford, England : 1990). 45(12)
Acquisition of drug resistance by cancer cells is attributed to various factors including alterations in apoptotic pathways, enhanced expression of multidrug resistance-associated proteins, altered drug metabolism or uptake and/or overexpression of c
Autor:
Fabrice Morel, Christophe Nicolas-Nicolaz, Elise Petit, Hanane Akhdar, Sophie Langouët, André Guillouzo
Publikováno v:
Toxicology in Vitro
Toxicology in Vitro, Elsevier, 2008, 22 (3), pp.632-42. ⟨10.1016/j.tiv.2007.12.004⟩
Toxicology in Vitro, 2008, 22 (3), pp.632-42. ⟨10.1016/j.tiv.2007.12.004⟩
Toxicology in Vitro, Elsevier, 2008, 22 (3), pp.632-42. ⟨10.1016/j.tiv.2007.12.004⟩
Toxicology in Vitro, 2008, 22 (3), pp.632-42. ⟨10.1016/j.tiv.2007.12.004⟩
International audience; Thiopurines (azathioprine, 6-mercaptopurine and 6-thioguanine) are therapeutic compounds widely administered in the clinic for their multiple uses (autoimmune diseases, post-transplant immunosuppression and cancer). Despite th