Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Hanan S El-Abhar"'
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Background Hepatic hypoxia/reoxygenation (H/R) insult is a critical issue in hepatic transplant and surgeries, profoundly influencing postoperative prognosis. One crucial pathomechanism in this condition is impaired autophagy flux, which dis
Externí odkaz:
https://doaj.org/article/b51556b500f64643b75e413fe81e6e17
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Endocannabinoid anandamide (AEA) has a physiological role in regulating renal blood flow, whereas its analogs ameliorated renal ischemia/reperfusion injury. Nonetheless, the role of AEA against mercuric chloride (HgCl2)-induced renal toxicit
Externí odkaz:
https://doaj.org/article/ce0c7ba427064a678b6c65fa8820b9d8
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 11, Pp 101818- (2023)
The potential health benefits of phytochemicals in preventing and treating diseases have gained increasing attention. Here, we proved that the methylated isoflavone prunetin possesses a reno-therapeutic effect against renal ischemia/reperfusion (I/R)
Externí odkaz:
https://doaj.org/article/c7071e38e6594eb1b3224f2656af771e
Autor:
Mohamed A. El-Emam, Samar El Achy, Dalaal M. Abdallah, Hanan S. El-Abhar, Mennatallah A. Gowayed
Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Mitoxantrone has proved efficacy in treatment of multiple sclerosis (MS). The fact that physical exercise could slow down the progression of disease and improve performance is still a debatable issue, hence; we aimed at studying w
Externí odkaz:
https://doaj.org/article/741dd1542d5a49fd8a9efac482d4f4b0
Autor:
Ayat I. Samra, Ahmed S. Kamel, Dalaal M. Abdallah, Mai A. Abd El Fattah, Kawkab A. Ahmed, Hanan S. El-Abhar
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3156 (2023)
Autism spectrum disorder (ASD) prevalence is emerging with an unclear etiology, hindering effective therapeutic interventions. Recent studies suggest potential renin–angiotensin system (RAS) alterations in different neurological pathologies. Howeve
Externí odkaz:
https://doaj.org/article/c31eda68a3a7481d8ca966568adf0d01
Autor:
Raghda T. Abdel-Latif, Walaa Wadie, Yousra Abdel-mottaleb, Dalaal M. Abdallah, Nabila N. El-Maraghy, Hanan S. El-Abhar
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 1, Pp 72-90 (2022)
Excessive interleukin (IL)-6 production is a driver for malignancy and drug resistance in colorectal cancer (CRC). Our study investigated a seven-week post-treatment with the anti-inflammatory drug, Diacerein (Diac), alone or in combination with 5-fl
Externí odkaz:
https://doaj.org/article/82a285cebf7d432abaef48c7736c15e1
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Although dysautonomia was documented in inflammatory bowel disease, with activation of the stress-related sympathetic system, the role of agonists/antagonists of the adrenergic receptors is not conclusive. Moreover, ulcerative colitis was recently li
Externí odkaz:
https://doaj.org/article/eefc2d32c3064966ae90782b46e6f429
Autor:
Hagar M. El-Sadek, Muhammad Y. AL-Shorbagy, Magdy M. Awny, Dalaal M. Abdallah, Hanan S. El-Abhar
Publikováno v:
Journal of Pharmacological Sciences, Vol 146, Iss 3, Pp 136-148 (2021)
Despite the documented renoprotective effect of pentoxifylline (PTX), a non-selective phosphodiesterase-4 inhibitor, the studies appraised only its anti-inflammatory/-oxidant/-apoptotic capacities without assessment of the possible involved trajector
Externí odkaz:
https://doaj.org/article/139b42f304af4369b1457410807da910
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Peganum harmala (P. harmala) is a folk medicinal herb used in the Sinai Peninsula (Egypt) as a remedy for central disorders. The main constituents, harmine and harmaline, have displayed therapeutic efficacy against Alzheimer’s disease (AD)
Externí odkaz:
https://doaj.org/article/ce8e95ce378442d5a027106fd6e53cd9
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Huntington’s disease (HD) is an autosomal dominant inherited neurodegenerative disease characterized by progressive motor, psychiatric, and cognitive abnormalities. The antidiabetic drug liraglutide possesses a neuroprotective potential against sev
Externí odkaz:
https://doaj.org/article/75c3c76bbfb14a1081b1c27b52719819