Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hanan N. Ghantous"'
Autor:
Ilona Bebenek, Caitlin Murphy, Lorrene A. Buckley, Hanan N. Ghantous, Eric C. Jensen, Aimee Hodowanec, Paul D. Cornwell
Publikováno v:
International Journal of Toxicology. 39:379-396
Drug development is a term used to define the entire process of bringing a new drug or device to market. It is an integrated, multidisciplinary endeavor that includes drug discovery, chemistry and pharmacology, nonclinical safety testing, manufacturi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a092df1d3e383ddb739e482ddabf546
https://doi.org/10.1177/1091581820939083
https://doi.org/10.1177/1091581820939083
Publikováno v:
International Journal of Toxicology. 39:141-150
Nonclinical toxicology studies are conducted to characterize the potential toxicities and establish a safe starting dose for new drugs in clinical studies, but the question remains as to how predictable/translatable the nonclinical safety findings ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb88c8ec1f1be71f9ff566a8e90ec6b1
https://doi.org/10.1177/1091581819894281
https://doi.org/10.1177/1091581819894281
Autor:
Kenneth L. Hastings, Hanan N. Ghantous, Nicola J. Stagg, Steven M. Gendel, Gregory S. Ladics, Robert V. House
Publikováno v:
International Journal of Toxicology. 32:4-10
A workshop entitled “Challenges and Opportunities in Evaluating Protein Allergenicity across Biotechnology Industries” was held at the 51st Annual Meeting of the Society of Toxicology (SOT) in San Francisco, California. The workshop was sponsored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfaeec83400f4c0eee6e2e86c60b1407
https://doi.org/10.1177/1091581812471864
https://doi.org/10.1177/1091581812471864
Publikováno v:
Nonclinical Safety Assessment: A Guide to International Pharmaceutical Regulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb7d7fcd2091156c558d99737e84b0bd
https://doi.org/10.1002/9781118517000.ch18
https://doi.org/10.1002/9781118517000.ch18
Autor:
Hanan N. Ghantous, David Jacobson-Kram
Publikováno v:
Pharmaceutical Sciences Encyclopedia
Genotoxic risks of pharmaceuticals are assessed by genetic toxicity assays. The assays rely on cytotoxicity to ensure assay validity. Performance of the assays is influenced by properties of the biopharmaceutical, synthesis techniques, product stabil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb988e3fb9c315dac43120b4e554a088
https://doi.org/10.1002/9780470571224.pse174
https://doi.org/10.1002/9780470571224.pse174