Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hanan M. Ragab"'
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-19 (2024)
Abstract Background The liver serves as a metabolic hub within the human body, playing a crucial role in various essential functions, such as detoxification, nutrient metabolism, and hormone regulation. Therefore, protecting the liver against endogen
Externí odkaz:
https://doaj.org/article/5116b34638d341bab0daa1b92e5f6b64
Autor:
Hanan M. Ragab, Nabwia S. Diab, Mahmoud AlElaimi, Azzah M. Alghamdi, Mohammed O. Farea, Adhban Farea
Publikováno v:
ACS Omega, Vol 9, Iss 20, Pp 22112-22122 (2024)
Externí odkaz:
https://doaj.org/article/5297a25637fa45b6875e877c241ff1ea
Publikováno v:
ACS Omega, Vol 9, Iss 2, Pp 2491-2503 (2024)
Externí odkaz:
https://doaj.org/article/6261ce44d0b84f09a2fc819f94c485e2
Autor:
Souraya A. Domiati, Khaled H. Abd El Galil, Mohammed A. S. Abourehab, Tamer M. Ibrahim, Hanan M. Ragab
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2179-2190 (2022)
A structure-guided modelling approach using COX-2 as a template was used to investigate the effect of replacing the chloro atom located at the chlorophenyl ring of amide-linked bipyrazole moieties, aiming at attaining better anti-inflammatory effect
Externí odkaz:
https://doaj.org/article/0059908b01c2425ca1e9b5923f422ca4
Autor:
Adnan A. Bekhit, Eskedar T. Lodebo, Ariaya Hymete, Hanan M. Ragab, Salma A. Bekhit, Kikuko Amagase, Afnan Batubara, Mohammed A. S. Abourehab, Alaa El-Din A. Bekhit, Tamer M. Ibrahim
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2320-2333 (2022)
Promising inhibitory activities of the parasite multiplication were obtained upon evaluation of in vivo antimalarial activities of new pyrazolylpyrazoline derivatives against Plasmodium berghei infected mice. Further evaluation of 5b and 6a against c
Externí odkaz:
https://doaj.org/article/c2480f42d54a4089bc0c1c71eabf297c
Autor:
Diana K. Ghobrial, Nefertiti El-Nikhely, Eman Sheta, Hanan M. Ragab, Sherif A. F. Rostom, Hesham Saeed, Ahmed Wahid
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 637 (2023)
Liver Fibrosis can be life-threatening if left untreated as it may lead to serious, incurable complications. The common therapeutic approach is to reverse the fibrosis while the intervention is still applicable. Celecoxib was shown to exhibit some an
Externí odkaz:
https://doaj.org/article/2599163c563449319823adfd395d4604
Autor:
Eman M. Othman, Amany A. Bekhit, Mohamed A. Anany, Thomas Dandekar, Hanan M. Ragab, Ahmed Wahid
Publikováno v:
Molecules, Vol 26, Iss 10, p 2961 (2021)
The present study reports the synthesis of new purine bioisosteres comprising a pyrazolo[3,4-d]pyrimidine scaffold linked to mono-, di-, and trimethoxy benzylidene moieties through hydrazine linkages. First, in silico docking experiments of the synth
Externí odkaz:
https://doaj.org/article/9d9dc9856fbf46fbbbd213cab0d0f10f
Autor:
Souraya A, Domiati, Khaled H, Abd El Galil, Mohammed A S, Abourehab, Tamer M, Ibrahim, Hanan M, Ragab
A structure-guided modelling approach using COX-2 as a template was used to investigate the effect of replacing the chloro atom located at the chlorophenyl ring of amide-linked bipyrazole moieties, aiming at attaining better anti-inflammatory effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1555d2a13923f206893507d9c69766
Publikováno v:
Bioorganic Chemistry. 86:557-568
In search of potent acetyl cholinesterase inhibitors with low hepatotoxicity for the treatment of Alzheimer's disease, introduction of a chloro substitution to tacrine and some of its analogs has proven to be beneficial in maintaining or potentiating
Autor:
H. Nakkash-Chmaisse, Souraya Domiati, A. El Mallah, K. H. Abd El Galil, Mohammed M. Mehanna, Hanan M. Ragab
Publikováno v:
Inflammation Research. 68:379-386
Since the synthesis of acetylsalicylic acid by Hoffmann in 1897, new classes of NSAIDs have been introduced; however, their side effects have limited their clinical applications. Consequently, our team has recently synthesized a novel bipyrazole comp