Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hanan Fael"'
Autor:
Ayca Yildiz Pekoz, Ozlem Akbal Dagistan, Hanan Fael, Meltem Culha, Aybige Erturk, Nur Sena Basarir, Gokben Sahin, Muge Serhatli, Gamze Cakirca, Saban Tekin, Leyla Semiha Sen, Mustafa Sevim, Lutfiye Mulazimoglu Durmusoglu, Berrak C. Yegen
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 2846-2854 (2022)
Favipiravir, an RNA-dependent RNA polymerase (RdRp) inhibitor, is used to treat patients infected with influenza virus and most recently with SARS-CoV-2. However, poor accumulation of favipiravir in lung tissue following oral administration has requi
Externí odkaz:
https://doaj.org/article/bdfea95241b44c239c118b5475ad3aa0
Autor:
Ozlem Akbal-Dagistan, Mustafa Sevim, Leyla Semiha Sen, Nur Sena Basarir, Meltem Culha, Aybige Erturk, Hanan Fael, Engin Kaptan, Serap Sancar, Lutfiye Mulazimoglu Durmusoglu, Berrak C. Yegen, Ayca Yildiz-Pekoz
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2375 (2022)
Favipiravir displays a rapid viral clearance, a high recovery rate and broad therapeutic safety; however, its oral administration was associated with systemic side effects in susceptible patients. Considering that the pulmonary route could provide a
Externí odkaz:
https://doaj.org/article/a405212c83bd41d2b88449c959d06126
Autor:
Rafael Barbas, Hanan Fael, Samuel Lee, Rebeca Ruiz, Christopher A. Hunter, Elisabet Fuguet, Clara Ràfols, Rafel Prohens
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2310 (2022)
The application of a computational screening methodology based on the calculation of intermolecular interaction energies has guided the discovery of new multicomponent solid forms of the oral antiviral Adefovir Dipivoxyl. Three new cocrystals with re
Externí odkaz:
https://doaj.org/article/c01151c7f62f4c8da8774c40da48264b
Publikováno v:
ADMET and DMPK, Vol 6, Iss 1, Pp 61-70 (2018)
The synthesis of cocrystals is presented as an alternative to improve the properties of active pharmaceutical ingredients, especially those related to solubility and dissolution rate. In this work the dissolution rate of ciprofloxacin, a zwitterionic
Externí odkaz:
https://doaj.org/article/bdff2d4522f349b58fe9361f3d675ab2
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 49 (2021)
A new cocrystal of Norfloxacin, a poorly soluble fluoroquinolone antibiotic, has been synthetized by a solvent-mediated transformation experiment in toluene, using resorcinol as a coformer. The new cocrystal exists in both anhydrous and monohydrate f
Externí odkaz:
https://doaj.org/article/f60bd92e12a749db892ba3789c999fff
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Pharmaceutics
Pharmaceutics, Vol 14, Iss 49, p 49 (2022)
Pharmaceutics; Volume 14; Issue 1; Pages: 49
Universidad de Barcelona
Pharmaceutics
Pharmaceutics, Vol 14, Iss 49, p 49 (2022)
Pharmaceutics; Volume 14; Issue 1; Pages: 49
A new cocrystal of Norfloxacin, a poorly soluble fluoroquinolone antibiotic, has been synthetized by a solvent-mediated transformation experiment in toluene, using resorcinol as a coformer. The new cocrystal exists in both anhydrous and monohydrate f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a11af3690a6f0f7a0655579d1fd9db1
http://hdl.handle.net/2445/184757
http://hdl.handle.net/2445/184757
Autor:
A. Levent Demirel, Hanan Fael
Publikováno v:
International journal of pharmaceutics. 600
In this study, new co-amorphous drug systems were designed using a pharmacologically relevant combination to improve the solubility and dissolution of indomethacin. Combinations of indomethacin-paracetamol (IND-PAR) as an anti-inflammatory/pain kille
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce9f596de589fe4b644eea9b0a10bc7
https://pubmed.ncbi.nlm.nih.gov/33675920
https://pubmed.ncbi.nlm.nih.gov/33675920
Autor:
Hanan Fael, A. Levent Demirel
Publikováno v:
International journal of pharmaceutics. 581
Co-amorphous systems have been increasingly investigated to improve the solubility and dissolution rate of poorly soluble drugs. Considering the ability of tannic acid (TA), a polyphenolic compound, to form hydrogen bonds with compounds that contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae9865a419a076826ec4f96d869daca
https://pubmed.ncbi.nlm.nih.gov/32243965
https://pubmed.ncbi.nlm.nih.gov/32243965
Autor:
A. Levent Demirel, Hanan Fael
Publikováno v:
RSC Advances
Nisin/polyanion Layer-by-Layer (LbL) films are reported to exhibit different mechanisms in antimicrobial efficacy depending on the type of polyanion. LbL films consisting of nisin as the polycationic component were prepared using two different polyan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0be79e8cd11bc531f7e51ea73c8e284
https://pubmed.ncbi.nlm.nih.gov/35498610
https://pubmed.ncbi.nlm.nih.gov/35498610
Publikováno v:
ADMET and DMPK, Vol 6, Iss 1, Pp 61-70 (2018)
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
ADMET and DMPK
Volume 6
Issue 1
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
ADMET and DMPK
Volume 6
Issue 1
The synthesis of cocrystals is presented as an alternative to improve the properties of active pharmaceutical ingredients, especially those related to solubility and dissolution rate. In this work the dissolution rate of ciprofloxacin, a zwitterionic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7381fa061b3a70d1befbf69ca918b28b
http://pub.iapchem.org/ojs/index.php/admet/article/view/497
http://pub.iapchem.org/ojs/index.php/admet/article/view/497