Výsledky vyhledávání - "Hanan F. Ismail"

Depletion of Neutrophils in IL-10−/− Mice Delays Clearance of Gastric Helicobacter Infection and Decreases the Th1 Immune Response to Helicobacter

Autor: Pamela Fick, Daniel J. Berg, Hanan F. Ismail, Richard G. Lynch, Juan Zhang

Publikováno v: The Journal of Immunology. 170:3782-3789

Gastric infection with Helicobacter induces a lymphocyte-rich mucosal inflammation that contains a minor population of neutrophilic granulocytes. The function of neutrophils in the local immune response to gastric Helicobacter infection remains unkno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d4691f284bf40c1f75c0324e468061
https://doi.org/10.4049/jimmunol.170.7.3782

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Rapid development of colitis in NSAID-treated IL-10–deficient mice

Autor: Juan Zhang, Hanan F. Ismail, Hector Alila, Daniel J. Berg, Joel V. Weinstock, Richard G. Lynch, Rifat Pamukcu, Steven A. Moore, Keith A. Earle

Publikováno v: Gastroenterology. 123:1527-1542

Background & Aims: Interleukin (IL)-10 is an anti-inflammatory and immune regulatory cytokine. IL-10–deficient mice (IL-10 −/− ) develop chronic inflammatory bowel disease (IBD), indicating that endogenous IL-10 is a central regulator of the mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308bcec26358324607d28232f65bb01b
https://doi.org/10.1053/gast.2002.1231527

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Role for Complement in Development of Helicobacter-Induced Gastritis in Interleukin-10-Deficient Mice

Autor: Hanan F. Ismail, Yi Wang, Daniel J. Berg, Richard G. Lynch, Juan Zhang

The mechanisms by which the immune response can eradicate gastricHelicobacterinfection are unknown. We hypothesized thatHelicobacter-induced activation of the complement system could promote both inflammation and eradication ofHelicobacterfrom the st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b482ac320a7d02b29048a09bc55b9651
https://europepmc.org/articles/PMC308887/

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Evidence for oxidative stress in NSAID-induced colitis in IL10-/- mice

Autor: Douglas R. Spitz, Garry R. Buettner, Richard G. Lynch, Daniel J. Berg, Larry W. Oberley, Hanan F. Ismail, Toshio Miyata, Carol A. Gunnett, Seiko Narushima, Juan Zhang, Shinya Toyokuni

Publikováno v: Free radical biologymedicine. 34(9)

The goal of this study was to evaluate for evidence of oxidative stress in colonic inflammation in a novel model of inflammatory bowel disease, nonsteroidal anti-inflammatory drug- (NSAID-) treated interleukin-10-deficient (IL10(-/-)) mice. IL10(-/-)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82328e7ddeccc6c9e634cf906d4a6c8b
https://pubmed.ncbi.nlm.nih.gov/12706496

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