Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hanan Bloomer"'
Autor:
Sydney J. Conner, Justinne R. Guarin, Thanh T. Le, Jackson P. Fatherree, Charlotte Kelley, Samantha L. Payne, Savannah R. Parker, Hanan Bloomer, Crystal Zhang, Kenneth Salhany, Rachel A. McGinn, Emily Henrich, Anna Yui, Deepti Srinivasan, Hannah Borges, Madeleine J. Oudin
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background Metastasis is the leading cause of death in breast cancer patients. For metastasis to occur, tumor cells must invade locally, intravasate, and colonize distant tissues and organs, all steps that require tumor cell migration. The m
Externí odkaz:
https://doaj.org/article/7a4e67d5306d4959bd38e1ceb19aa28a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3773-3780 (2019)
DNA double-strand breaks (DSBs) are especially toxic DNA lesions that, if left unrepaired, can lead to wide-ranging genomic instability. Of the pathways available to repair DSBs, the most accurate is homologous recombination (HR), where a homologous
Externí odkaz:
https://doaj.org/article/946cc2c36a24469cbc2ef0010ceec2de
Autor:
Juan Pablo Ruiz, Guibin Chen, Juan Jesus Haro Mora, Keyvan Keyvanfar, Chengyu Liu, Jizhong Zou, Jeanette Beers, Hanan Bloomer, Husam Qanash, Naoya Uchida, John F. Tisdale, Manfred Boehm, Andre Larochelle
Publikováno v:
Stem Cell Research, Vol 41, Iss , Pp - (2019)
One of the most promising objectives of clinical hematology is to derive engraftable autologous hematopoietic stem cells (HSCs) from human induced pluripotent stem cells (iPSCs). Progress in translating iPSC technologies to the clinic relies on the a
Externí odkaz:
https://doaj.org/article/1b9b82545fe44b4484395f6db5b7fa07
Autor:
Richard H. Smith, Hanan Bloomer, Danielle Fink, Keyvan Keyvanfar, Md Nasimuzzaman, Fátima Sancheznieto, Roop Dutta, Kacey Guenther Bui, Luigi J. Alvarado, Thomas R. Bauer, Dennis D. Hickstein, David W. Russell, Punam Malik, Johannes C.M. van der Loo, Steven L. Highfill, Douglas B. Kuhns, Mehdi Pirooznia, Andre Larochelle
Publikováno v:
Human gene therapy. 33(23-24)
Publikováno v:
Molecular Therapy. 29:1611-1624
Ex vivo gene correction of hematopoietic stem and progenitor cells (HSPCs) has emerged as a promising therapeutic approach for treatment of inherited human blood disorders. Use of engineered nucleases to target therapeutic transgenes to their endogen
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3773-3780 (2019)
DNA double-strand breaks (DSBs) are especially toxic DNA lesions that, if left unrepaired, can lead to wide-ranging genomic instability. Of the pathways available to repair DSBs, the most accurate is homologous recombination (HR), where a homologous
Publikováno v:
Accounts of chemical research. 54(21)
Since the U.S. Food and Drug Administration (FDA) granted emergency use authorization for two mRNA vaccines against SARS-CoV-2, mRNA-based technology has attracted broad attention from the scientific community to investors. When delivered intracellul
Publikováno v:
Adv Drug Deliv Rev
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) system has revolutionized the ability to edit the mammalian genome, providing a platform for the correction of pathogenic mutations and further inve