Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hanan, Armanious"'
Publikováno v:
Cellular Signalling. 25:381-388
It was previously reported that β-catenin contributes to the tumorigenesis of ALK-positive anaplastic large cell lymphoma (ALK + ALCL), and the oncogenic effects of β-catenin in these tumors are promoted by NPM-ALK, an abnormal fusion protein chara
Publikováno v:
Blood. 117:6237-6246
One of the main functions of A Disintegrin and Metalloproteinase 10 (ADAM10) is to regulate the bioavailability of adhesion molecules and ligands to various cellular-signaling receptors. Constitutive activation of ADAM10 has been implicated in the pa
Publikováno v:
Human Pathology. 41:1657-1663
Glycogen synthase kinase 3β, recently found to be functionally abnormal in various types of human disease, is negatively regulated by the PI3K/Akt signaling pathway. As Akt is constitutively activated in a subset of breast cancer, we hypothesized th
Autor:
Pascal Gelebart, Robert J. Ingham, Mona Anand, Abdulraheem Alshareef, Raymond Lai, Hanan Armanious, Samar A. Hegazy
Publikováno v:
Cellular signalling. 25(1)
Our previous oligonucleotide array studies revealed that ALK-positive anaplastic large cell lymphoma (ALK + ALCL) express high levels of the disheveled proteins (Dvls), a family of proteins that is integral to the Wnt signaling pathways. In this stud
Publikováno v:
International journal of clinical and experimental pathology. 3(7)
The expression of β-catenin detectable by immunohistochemistry has been reported to be prognostically important in breast cancer. In this study, we investigated the mechanism by which β-catenin is regulated in breast cancer cells. Our analysis of t
Autor:
Randy, Chung, Anthea C, Peters, Hanan, Armanious, Mona, Anand, Pascal, Gelebart, Raymond, Lai
Publikováno v:
International journal of clinical and experimental pathology. 3(3)
GSK-3beta, a biologically important signalling protein, is regulated by the Wnt canonical and the PI3K/Akt pathways. We recently reported that mantle cell lymphoma (MCL) frequently shows evidence of GSK-3beta inactivation, since GSK-3beta is phoshory
Autor:
Hanan Armanious, Jennifer Dien Bard, Hesham M. Amin, Raymond Lai, Anthea Peters, Mona Anand, Pascal Gelebart
Publikováno v:
Blood. 112(13)
Aberrations of the Wnt canonical pathway (WCP) are known to contribute to the pathogenesis of various types of cancer. We hypothesize that these defects may exist in mantle cell lymphoma (MCL). Both the upstream and downstream aspects of WCP were exa
Autor:
Mona Anand, Raymond Lai, Pascal Gelebart, Samar A. Hegazy, Robert J. Ingham, Abdulraheem Alshareef, Hanan Armanious
Publikováno v:
Cellular Signalling. 25:580
Publikováno v:
Clinical Cancer Research. 16:A1-A1
Glycogen synthase kinase 3β (GSK-3β), recently found to be functionally abnormal in various types of human disease, is negatively regulated by the PI3K/Akt signaling pathway. Since Akt is constitutively activated in a subset of breast cancer, we hy