Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Hanan, Alwaseem"'
Autor:
Hanan Alwaseem, Simone Giovani, Michele Crotti, Kevin Welle, Craig T. Jordan, Sina Ghaemmaghami, Rudi Fasan
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 841-857 (2021)
Externí odkaz:
https://doaj.org/article/7fb1f4907aaf4ca48e778ec8357799ef
Autor:
James Russell, Louise Fanchon, Hanan Alwaseem, Henrik Molina, Isabella O’Donoghue, Amber Bahr, Elisa deStanchina, Nagavarakishore Pillarsetty, John L. Humm
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract Previously published digital autoradiography of 3H‐labeled capecitabine reveals a near‐uniform distribution of activity throughout a murine pancreatic model. This is in contrast both to 14C‐labeled gemcitabine, and established expectat
Externí odkaz:
https://doaj.org/article/9a2617618920471fbdb6fb46405f3a90
Autor:
Yiming Niu, Xiao Tao, George Vaisey, Paul Dominic B Olinares, Hanan Alwaseem, Brian T Chait, Roderick MacKinnon
Publikováno v:
eLife, Vol 10 (2021)
Mechanosensitive ion channels mediate transmembrane ion currents activated by mechanical forces. A mechanosensitive ion channel called TACAN was recently reported. We began to study TACAN with the intent to understand how it senses mechanical forces
Externí odkaz:
https://doaj.org/article/56fa99acf7c344108bdf92b22b48fc42
Autor:
Chaitanya A Kulkarni, Sergiy M Nadtochiy, Leslie Kennedy, Jimmy Zhang, Sophea Chhim, Hanan Alwaseem, Elizabeth Murphy, Dragony Fu, Paul S Brookes
Publikováno v:
eLife, Vol 9 (2020)
Alkb homolog 7 (ALKBH7) is a mitochondrial α-ketoglutarate dioxygenase required for DNA alkylation-induced necrosis, but its function and substrates remain unclear. Herein, we show ALKBH7 regulates dialdehyde metabolism, which impacts the cardiac re
Externí odkaz:
https://doaj.org/article/0dc515db99d74ef0bd80e3abdb1bbe69
Autor:
Timothy C. Kenny, Artem Khan, Yeeun Son, Lishu Yue, Søren Heissel, Anurag Sharma, H. Amalia Pasolli, Yuyang Liu, Eric R. Gamazon, Hanan Alwaseem, Richard K. Hite, Kıvanç Birsoy
Publikováno v:
Cell Metabolism.
Autor:
Dennis J. Hsu, Jenny Gao, Norihiro Yamaguchi, Alexandra Pinzaru, Qiushuang Wu, Nandan Mandayam, Maria Liberti, Søren Heissel, Hanan Alwaseem, Saeed Tavazoie, Sohail F. Tavazoie
Publikováno v:
Science advances. 9(1)
Utilization of specific codons varies between organisms. Cancer represents a model for understanding DNA sequence evolution and could reveal causal factors underlying codon evolution. We found that across human cancer, arginine codons are frequently
Autor:
Dennis J. Hsu, Jenny Gao, Norihiro Yamaguchi, Alexandra Pinzaru, Nandan Mandayam, Maria Liberti, Søren Heissel, Hanan Alwaseem, Saeed Tavazoie, Sohail F. Tavazoie
Utilization of specific codons varies significantly across organisms. Cancer represents a model for understanding DNA sequence evolution and could reveal causal factors underlying codon evolution. We found that across human cancer, arginine codons ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f2a6d490e25184f298f8dd662847ef
https://doi.org/10.1101/2023.01.02.521806
https://doi.org/10.1101/2023.01.02.521806
Autor:
Timothy C. Kenny, Artem Khan, Yeeun Son, Lishu Yue, Søren Heissel, Eric R. Gamazon, Hanan Alwaseem, Richard Hite, Kıvanç Birsoy
Genome-wide association studies (GWAS) of serum metabolites have the potential to uncover genes that influence human metabolism. Here, we combined an integrative genetic analysis associating serum metabolites to membrane transporters with a coessenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42162d0b2517321f2061bc75063fa774
https://doi.org/10.1101/2022.10.05.509986
https://doi.org/10.1101/2022.10.05.509986
Autor:
Rudi Fasan, Hanan Alwaseem
Publikováno v:
Protein Engineering
Autor:
Behnam Javidfar, Wei-Dong Yao, Fatemeh Haghighi, M. Foo, C. P. Watkins, C. G. Hahn, Søren Heissel, H. L. Phillips, Schahram Akbarian, Sohit Miglani, Jennifer Blaze, Henrik Molina, B. Rostandy, Zachary T. Pennington, Albertas Navickas, Tao Pan, Hani Goodarzi, Denise J. Cai, Hanan Alwaseem, A. Plaza-Jennings, Sergio Espeso-Gil, Christopher D. Katanski, Hosseinali Asgharian
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Epitranscriptomic mechanisms linking tRNA function and the brain proteome to cognition and complex behaviors are not well described. Here, we report bi-directional changes in depression-related behaviors after genetic disruption of neuronal tRNA cyto