Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Hanah Margalit"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract In bacteria, determination of the 3’ termini of transcripts plays an essential role in regulation of gene expression, affecting the functionality and stability of the transcript. Several experimental approaches were developed to identify t
Externí odkaz:
https://doaj.org/article/19808b9c93444d2eac040ba7e96891f6
Autor:
Mor Rubinstein, Andrei Makhon, Yelena Losev, Gal Zizelski Valenci, Yair E. Gatt, Hanah Margalit, Ephraim Fass, Ina Kutikov, Omer Murik, David A. Zeevi, Michal Savyon, Luba Tau, Hasia Kaidar Shwartz, Zeev Dveyrin, Efrat Rorman, Israel Nissan
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Coinfection of HIV and multidrug-resistant tuberculosis (MDR-TB) presents significant challenges in terms of the treatment and prognosis of tuberculosis, leading to complexities in managing the disease and impacting the overall outcome for TB patient
Externí odkaz:
https://doaj.org/article/796d15d07df242cb80b578e11bdb0b03
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT Bacteria adapt to their host by mutating specific genes and by reprogramming their gene expression. Different strains of a bacterial species often mutate the same genes during infection, demonstrating convergent genetic adaptation. However,
Externí odkaz:
https://doaj.org/article/08435bb3722141e3a347c9075b85159a
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The genomic revolution and subsequent advances in large-scale genomic and transcriptomic technologies highlighted hidden genomic treasures. Among them stand out non-coding small RNAs (sRNAs), shown to play important roles in post-transcriptional regu
Externí odkaz:
https://doaj.org/article/5b8f2476b3644a6f91d447add060d82b
Autor:
Raya Faigenbaum-Romm, Avichai Reich, Yair E. Gatt, Meshi Barsheshet, Liron Argaman, Hanah Margalit
Publikováno v:
Cell Reports, Vol 30, Iss 9, Pp 3127-3138.e6 (2020)
Summary: Bacterial small RNAs (sRNAs) are posttranscriptional regulators of gene expression that base pair with complementary sequences on target mRNAs, often in association with the chaperone Hfq. Here, using experimentally identified sRNA-target pa
Externí odkaz:
https://doaj.org/article/273e28c79776404c988bdc8a5ff30adc
Autor:
Yuval Malka, Avital Steiman-Shimony, Eran Rosenthal, Liron Argaman, Leonor Cohen-Daniel, Eliran Arbib, Hanah Margalit, Tommy Kaplan, Michael Berger
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Most mammalian genes contain alternative polyadenylation sites. Here, the authors provide evidence that mRNA can be cleaved post-transcriptionally to generate mRNAs with shorter 3-´UTRs and stable autonomous uncapped 3´-UTR sequences.
Externí odkaz:
https://doaj.org/article/ce1dad09340e458a87035489f306649d
Autor:
Saurabh Bhattacharya, Amit K. Baidya, Ritesh Ranjan Pal, Gideon Mamou, Yair E. Gatt, Hanah Margalit, Ilan Rosenshine, Sigal Ben-Yehuda
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 334-342.e10 (2019)
Summary: We have previously described the existence of membranous nanotubes, bridging adjacent bacteria, facilitating intercellular trafficking of nutrients, cytoplasmic proteins, and even plasmids, yet components enabling their biogenesis remain elu
Externí odkaz:
https://doaj.org/article/821f769b77ca4ce9afa3f6ace8853e11
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 1, p e1002341 (2012)
Many protein-protein interactions are mediated by domain-motif interaction, where a domain in one protein binds a short linear motif in its interacting partner. Such interactions are often involved in key cellular processes, necessitating their tight
Externí odkaz:
https://doaj.org/article/be5d70eec58f4a169a9d1c9a8b5527f6
Autor:
Zohar Itzhaki, Hanah Margalit
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34503 (2012)
Genome sequencing of various individuals or isolates of the same species allows studying the polymorphism level of specific proteins and protein domains. Here we ask whether domains that are known to be involved in mediating protein-protein interacti
Externí odkaz:
https://doaj.org/article/e7d58ea5f96f46ff8a2d12e0d96dfcff
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 1 (2012)
Externí odkaz:
https://doaj.org/article/25f3e9381b53496f960cd792b14aa76c