Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Hanae Nakashima"'
Autor:
Osamu Yokota, Tomoko Miki, Hanae Nakashima-Yasuda, Hideki Ishizu, Takashi Haraguchi, Chikako Ikeda, Masato Hasegawa, Akinori Miyashita, Takeshi Ikeuchi, Naoto Nishikawa, Shintaro Takenoshita, Koichiro Sudo, Seishi Terada, Manabu Takaki
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Agyrophilic grains (AGs) are age-related limbic-predominant lesions in which four-repeat tau is selectively accumulated. Because previous methodologically heterogeneous studies have demonstrated inconsistent findings on the relationship betw
Externí odkaz:
https://doaj.org/article/e40d2050a9d34e42a9b032d3ca1df442
Autor:
Osamu Yokota, Tomoko Miki, Hanae Nakashima-Yasuda, Hideki Ishizu, Takashi Haraguchi, Chikako Ikeda, Akinori Miyashita, Takeshi Ikeuchi, Shintaro Takenoshita, Seishi Terada, Manabu Takaki
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-7 (2023)
Externí odkaz:
https://doaj.org/article/dffc8d04c8344d9b825dbdcbc538391a
Autor:
Shintaro Takenoshita, Keiko Kondo, Keiichi Okazaki, Akihiko Hirao, Keiko Takayama, Keisuke Hirayama, Hiroyuki Asaba, Kenji Nakata, Hideki Ishizu, Hiromi Takahashi, Hanae Nakashima-Yasuda, Yasue Sakurada, Kengo Fujikawa, Osamu Yokota, Norihito Yamada, Seishi Terada, Middle Western Japan-Dementia Study (mid-Dem study)
Publikováno v:
BMC Geriatrics, Vol 17, Iss 1, Pp 1-5 (2017)
Abstract Background It is widely supposed that there is no benefit, including extended survival and decreased rate of pneumonia, in patients with severe dementia receiving enteral tube feeding (TF). However, there have been few studies comparing the
Externí odkaz:
https://doaj.org/article/5ca003b26ea44741acbb194c1331e2f4
Autor:
Hanae Nakashima, Yoshinori Nishimoto, Satoshi Yamada, Kensuke Okada, Haruhiko Hoshino, Fumie Konoeda, Ryuichiro Yagi
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 28:229-231
Medullary hemorrhage is quite rare among brain stem hemorrhage cases, thus the clinical course remains unclear. In the medulla oblongata, respiratory centers are located and previous reports indicate that medullary lesions have possible relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59bb40b668aa6cfe5ec599d23d046b9
https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.09.027
https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.09.027
Autor:
Shugo Tohyama, Keiichi Fukuda, Tomohiko Umei, Ryo Aeba, Shu Takeda, Rie Wada, Kohei Inagawa, Masaki Ieda, Kazutaka Miyamoto, Yoshifumi Kawamura, Ruri Kaneda, Hanae Nakashima, Naoto Muraoka, Mari Isomi, Mizuha Akiyama, Hisayuki Hashimoto, Hiroyuki Yamakawa, Naoki Goshima, Taketaro Sadahiro, Toru Fukuda, Hiroyuki Yamagishi, Takahiko Nishiyama
Publikováno v:
The EMBO Journal. 33:1565-1581
Fibroblasts can be directly reprogrammed into cardiomyocyte-like cells (iCMs) by overexpression of cardiac transcription factors or microRNAs. However, induction of functional cardiomyocytes is inefficient, and molecular mechanisms of direct reprogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f191b927dd2ce7ee023973a8724451c
https://doi.org/10.15252/embj.201387605
https://doi.org/10.15252/embj.201387605
Autor:
Etsuko Oshima, Yosuke Uchitomi, Takeshi Ishihara, Jun Naohara, Hanae Nakashima-Yasuda, Seishi Terada, Shigeto Nagao, Chikako Ikeda, Osamu Yokota
Publikováno v:
Brain Pathology. 23:633-644
To clarify whether long-term oral ingestion of aluminum (Al) can increase tau aggregation in mammals, we examined the effects of oral Al administration on tau accumulation, apoptosis in the central nervous system (CNS) and motor function using tau tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba6e267d6cc43911ab645d5884ed7a5b
https://doi.org/10.1111/bpa.12059
https://doi.org/10.1111/bpa.12059
Autor:
Gideon Dreyfuss, Hanae Nakashima-Yasuda, Linda K. Kwong, Virginia M.-Y. Lee, Lionel M. Igaz, Stephen J. Kolb, Hans A. Kretzschmar, John Q. Trojanowski, Manuela Neumann
Publikováno v:
Acta Neuropathologica. 113:543-548
TDP-43 was recently identified as the major disease protein in neuronal inclusions in frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U). TDP-43 becomes redistributed from the nucleus to the cytoplasm, ubiquitinated, hyperp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0bb52625d3e19dd74c43042b3a7ba3
https://doi.org/10.1007/s00401-007-0221-x
https://doi.org/10.1007/s00401-007-0221-x
Autor:
Ryong Woon Shin, Alfredo Shimabuku, Tetsuyuki Kitamoto, Hanae Nakashima, Koichi Ogino, Takeshi Ishihara, Takao Taki
Publikováno v:
Acta Neuropathologica. 113:627-636
Abnormal accumulation of Abeta and tau in senile plaques (SP) and neurofibrillary tangles (NFTs) is a key event in Alzheimer's disease (AD). Here, we show that T668-phosphorylated cytoplasmic domain of APP (pT668-ACD) accumulates Abeta and tau in AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ecf4e571b0a0f6d379c19d537de8fa6
https://doi.org/10.1007/s00401-007-0211-z
https://doi.org/10.1007/s00401-007-0211-z
Autor:
S. Pilar Suguimoto, Etsuko Oshima, Takashi Hamamura, Osamu Yokota, Virginia M.-Y. Lee, Seishi Terada, Hanae Nakashima, Aki Kugo, Takeshi Ishihara, Shigetoshi Kuroda, John Q. Trojanowski
Publikováno v:
Acta Neuropathologica. 110:547-556
Lithium, a widely used drug for treating affective disorders, is known to inhibit glycogen synthase kinase-3 (GSK-3), which is one of the major tau kinases. Thus, lithium could have therapeutic benefit in neurodegenerative tauopathies by reducing tau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faaa33346b2a4e97a5db7e40a88153c4
https://doi.org/10.1007/s00401-005-1087-4
https://doi.org/10.1007/s00401-005-1087-4
Autor:
Hanae Nakashima, Aki Kugo, Osamu Yokota, Ken Sasaki, Yuji Tanaka, Yoshikatsu Fujisawa, Seishi Terada, Tadao Nakashima, Takeshi Ishihara, Shigetoshi Kuroda, Yoshihiko Nakashima, Hideki Ishizu
Publikováno v:
Journal of Geriatric Psychiatry and Neurology. 18:142-148
Delusion of theft and phantom intruder delusion are among the most frequent delusions in dementia. The purpose of this study was to clarify the clinical characteristics of patients with these symptoms. The authors conducted a questionnaire survey; it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07240a958766be270483b436995d5c8a
https://doi.org/10.1177/0891988705277538
https://doi.org/10.1177/0891988705277538