Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hana Vlčková"'
Autor:
Jana Pourová, Přemysl Mladěnka, Lucia Mitašík, Iveta Nejmanová, Lucie Nováková, Maria Carmen Catapano, Hana Vlčková, Ondřej Kotland
Publikováno v:
Journal of Separation Science. 44:1893-1903
Sensitive analysis of very low-molecular weight metabolites using liquid chromatography with quadrupole-time-of-flight mass spectrometry is challenging due to the high losses of ions in a time-of-flight analyzer. Improvement in sensitivity for these
Autor:
Michele Protti, Frantisek Svec, Laura Mercolini, Vladimír Buchta, Hana Vlčková, Ondřej Jung, Lucie Nováková, Veronika Pilařová
The new ultra-high performance liquid chromatography method with tandem mass spectrometry detection (UHPLC-MS/MS) has been optimized to allow fast, selective, and high-throughput analysis of two Candida albicans quorum sensing molecules (QSM), farnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668d8d09e7e46a89a1b357c957b0ec36
http://hdl.handle.net/11585/762365
http://hdl.handle.net/11585/762365
Autor:
Alexandr Hrabálek, Petr Pavek, Pavel Sychra, Oto Pavliš, Lenka Valášková, Kateřina Vávrová, Galina Karabanovich, Hana Vlčková, Jaroslav Roh, Alejandro Carazo, Jiřina Stolaříková, Věra Klimešová, Jan Němeček
Publikováno v:
Bioorganic & Medicinal Chemistry. 25:5468-5476
In this work, four series of tertiary amine-containing derivatives of 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents were prepared, and their in vitro antimycobacterial effects were evaluated. We found that the studied compounds sho
Autor:
Katarína Mikušová, Galina Karabanovich, Věra Klimešová, Alexandr Hrabálek, Karin Savková, Jan Dušek, Jaroslav Roh, Jana Korduláková, Ivona Pavkova, Oto Pavliš, Zuzana Konyariková, Tomas Kucera, Kateřina Vávrová, Jiřina Stolaříková, Jan Korábečný, Petr Pavek, Klára Konečná, Ondřej Jand’ourek, Hana Vlčková, Stanislav Huszár
Publikováno v:
Journal of medicinal chemistry. 62(17)
We report herein the discovery of 3,5-dinitrophenyl 1,2,4-triazoles with excellent and selective antimycobacterial activities against Mycobacterium tuberculosis strains, including clinically isolated multidrug-resistant strains. Thorough structure-ac
Publikováno v:
Bioanalysis. 8:333-349
Background: Statins are the microsomal 3-hydroxy-3methylglutaryl-coenzyme A reductase inhibitors used for the treatment of hypercholesterolemia. Some recent studies revealed also the extra-lipid effects and anticancer activities. Due to the wide inci
Publikováno v:
TrAC Trends in Analytical Chemistry. 63:55-64
In recent years, the popularity of hydrophilic interaction chromatography (HILIC) in the analysis of small polar and ionizable molecules increased substantially. A large number of new stationary phases with sub-2-µm and superficially porous particle
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 151
The presented work describes the development and validation of a rapid UHPLC-UV method using a fused core particle column with an RP-Amide stationary phase for the separation and quantitative analysis of caffeoylquinic and di-caffeoylquinic acids in
Publikováno v:
Bioanalysis. 9(11)
Aim: Micro-SPE in pipette tips (μ-SPE-PT) with particle sorbent has never been used in small-molecule drug analysis. Methodology & results: μ-SPE-PT was used for the extraction of statins from biological materials followed by UHPLC–MS/MS. The com
Autor:
Kateřina Štětková, Helena Tomšíková, Lucie Nováková, Petr Solich, Kateřina Ježková, Hana Vlčková
Publikováno v:
Journal of Separation Science. 37:1297-1307
The retention behavior of a large group of analytes (35) with varied properties (pKa and logP) was studied on eight hydrophilic interaction LC columns with different surfaces, stationary phase chemistries, and types of particles. The acetonitrile con
Publikováno v:
Talanta. 93:99-105
In this study, the selectivity, retention properties, peak shape and loading capacity for bases were practically evaluated using two UHPLC mixed-mode hybrid CSH stationary phases modified by C18 or Phenyl group. The data were compared with the data o