Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors

Autor: Martin Selinger, Pavlína Věchtová, Hana Tykalová, Petra Ošlejšková, Michaela Rumlová, Ján Štěrba, Libor Grubhoffer

Publikováno v: Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2759-2777 (2022)

Tick-borne encephalitis virus (TBEV), the most medically relevant tick-transmitted flavivirus in Eurasia, targets the host central nervous system and frequently causes severe encephalitis. The severity of TBEV-induced neuropathogenesis is highly cell

Externí odkaz: https://doaj.org/article/86a306273e9145be900383d97905308f

Tick-Borne Encephalitis Virus Adaptation in Different Host Environments and Existence of Quasispecies

Autor: Renata Helmová, Václav Hönig, Hana Tykalová, Martin Palus, Lesley Bell-Sakyi, Libor Grubhoffer

Publikováno v: Viruses, Vol 12, Iss 8, p 902 (2020)

A highly virulent strain (Hypr) of tick-borne encephalitis virus (TBEV) was serially subcultured in the mammalian porcine kidney stable (PS) and Ixodes ricinus tick (IRE/CTVM19) cell lines, producing three viral variants. These variants exhibited dis

Externí odkaz: https://doaj.org/article/26b04d569bc84d10bebb63c031711cc8

Transcriptional and translation shut-off in TBEV infected neural cells and involvement of viral C protein

Autor: Hana Tykalová, Martin Selinger, Esther Schnettler, Alain Kohl, Pavlína Věchtová, Libor Grubhoffer, Ján Štěrba

Publikováno v: Access Microbiology. 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc99a6f9a24996af2f2eafa6abb57a21
https://doi.org/10.1099/acmi.imav2019.po0041

Ticks and tick-borne pathogens in South Bohemia (Czech Republic) – Spatial variability in Ixodes ricinus abundance, Borrelia burgdorferi and tick-borne encephalitis virus prevalence

Autor: V. Vetiskova, Nataliia Rudenko, Jarmila Sterbova, Jan Sterba, V. Dornakova, Jan Erhart, Libor Grubhoffer, Václav Hönig, Patrik Kilian, Maryna Golovchenko, Hana Tykalová, Petr Halas, Z. Simonova, Pavel Švec, Zuzana Vavrušková

Publikováno v: Ticks and Tick-borne Diseases. 6:559-567

Spatial distribution of Ixodes ricinus tick host-seeking activity, as well as prevalence of Borrelia burgdorferi sensu lato and tick-borne encephalitis virus (TBEV) were studied in the TBE endemic area of South Bohemia (Czech Republic). High variabil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0241d405b3b00dc696e72d7e42d90b0e
https://doi.org/10.1016/j.ttbdis.2015.04.010

Ixodes scapularis and Ixodes ricinus tick cell lines respond to infection with tick-borne encephalitis virus:transcriptomic and proteomic analysis

Autor: Mick Watson, Margarita Villar, José de la Fuente, Marina Popara, Libor Grubhoffer, Lesley Bell-Sakyi, Julia Loecherbach, Daniel Růžek, John K. Fazakerley, Sabine Weisheit, Hana Tykalová

Publikováno v: Weisheit, S, Villar, M, Tykalová, H, Popara, M, Loecherbach, J, Watson, M, Růžek, D, Grubhoffer, L, de la Fuente, J, Fazakerley, J K & Bell-Sakyi, L 2015, ' Ixodes scapularis and Ixodes ricinus tick cell lines respond to infection with tick-borne encephalitis virus : transcriptomic and proteomic analysis ', Parasites and Vectors, vol. 8, no. 1, pp. 599 . https://doi.org/10.1186/s13071-015-1210-x
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This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.-- et al.
[Background]: Ixodid ticks are important vectors of a wide variety of viral, bacterial and protozoan pathogens of medical and vet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b33f10d36ac0d8aeec39deb2dfccb80
https://www.pure.ed.ac.uk/ws/files/22165240/s13071_015_1210_x.pdf