Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hana Remešová"'
Autor:
Šárka Šestáková, Cyril Šálek, Dávid Kundrát, Ela Cerovská, Jan Vydra, Ivana Ježíšková, Adam Folta, Jiří Mayer, Petr Cetkovský, Hana Remešová
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Changes in DNA methylation are common events in the pathogenesis of acute myeloid leukemia (AML) and have been repeatedly reported as associated with prognosis. However, studies integrating these numerous and potentially prognosti
Externí odkaz:
https://doaj.org/article/445a337be93740f6998ac1681e644cb8
Autor:
Šárka Šestáková, Ela Cerovská, Cyril Šálek, Dávid Kundrát, Ivana Ježíšková, Adam Folta, Jiří Mayer, Zdeněk Ráčil, Petr Cetkovský, Hana Remešová
Publikováno v:
Clinical Epigenetics. 14
Background Multiple studies have reported the prognostic impact of DNA methylation changes in acute myeloid leukemia (AML). However, these epigenetic markers have not been thoroughly validated and therefore are still not considered in clinical practi
Autor:
Petr Cetkovský, Šárka Šestáková, Hana Remešová, Cyril Šálek, Zdeněk Krejčík, Zdeněk Ráčil, Pavla Pecherkova, Adam Folta, Jiří Mayer, Michaela Dostalova Merkerova, Ela Cerovska
Publikováno v:
Cancer Biomarkers. 25:43-51
Background Aberrant epigenetic patterns are a hallmark of acute myeloid leukemia (AML). Mutations in profound epigenetic regulators DNMT3A and IDH1/2 often occur concurrently in AML. Objectives The aim was to analyze DNA methylation, hydroxymethylati
The Italian Society for Near-Infrared Spectroscopy (SISNIR), in collaboration with the InnoRenew CoE and the University of Primorska, organized the National Symposium of NIR Spectroscopy. The event entitled ‘NIRITALIA online, waiting for Slovenia 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e434683e463015e468551b6c435d2f
https://doi.org/10.5281/zenodo.4565231
https://doi.org/10.5281/zenodo.4565231
Autor:
Zdeněk Ráčil, Petr Cetkovský, Šárka Šestáková, Ivana Ježíšková, Hana Remešová, Jiří Mayer, Cyril Šálek, David Kundrat
Publikováno v:
Blood. 136:32-33
Changes in DNA methylation are characteristic for patients with acute myeloid leukemia (AML) and many studies have reported the prognostic significance of these epigenetic aberrations. We aimed for a complex evaluation of DNA methylation changes in A
Publikováno v:
Biological Procedures
Here, we present a practical overview of four commonly used validation methods for DNA methylation assessment: methylation specific restriction endonucleases (MSRE) analysis, pyrosequencing, methylation specific high-resolution DNA melting (MS-HRM) a
Autor:
Ivana Jeziskova, Zdenek Racil, Petr Cetkovsky, Pavel Zak, Anna Durinikova, Nikola Tom, Pavel Jindra, Tomáš Szotkowski, Martin Čulen, Jiri Mayer, Tereza Hlubinková, Lukáš Semerád, Adam Folta, Zdenka Herudkova, Jan Vydra, Veronika Janečková, Dana Dvorakova, Hana Remešová, Ela Cerovska
Publikováno v:
British Journal of Haematology.
In this multi-centre study, we analysed the prognostic impact of mutations in 19 genes associated with myeloid malignancies in 258 newly diagnosed acute myeloid leukaemia patients (aged 19-70 years) undergoing intensive therapy. We identified five pa
Autor:
Ela Cerovska, Cyril Salek, David Kundrat, Sarka Sestakova, Adam Pesek, Ivana Brozinova, Monika Belickova, Hana Remesova
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115930- (2024)
Introduction: To date, no chemoresistance predictors are included in acute myeloid leukaemia (AML) prognostic scoring systems to distinguish responding and refractory AML patients prior to chemotherapy. ABC transporters have been described as alterin
Externí odkaz:
https://doaj.org/article/a2bb784d5abd403ba1359e02d33aae76
Autor:
Peter Holicek, Iva Truxova, Jana Rakova, Cyril Salek, Michal Hensler, Marek Kovar, Milan Reinis, Romana Mikyskova, Josef Pasulka, Sarka Vosahlikova, Hana Remesova, Iva Valentova, Daniel Lysak, Monika Holubova, Petr Kaspar, Jan Prochazka, Lenka Kasikova, Radek Spisek, Lorenzo Galluzzi, Jitka Fucikova
Publikováno v:
Cell Death and Disease, Vol 14, Iss 3, Pp 1-12 (2023)
Abstract While type I interferon (IFN) is best known for its key role against viral infection, accumulating preclinical and clinical data indicate that robust type I IFN production in the tumor microenvironment promotes cancer immunosurveillance and
Externí odkaz:
https://doaj.org/article/f8edc52886a84c80a88c6cee32d03c15
Autor:
Monika Belickova, Jaroslav Cermak, Katarina Szikszai, Zdenek Krejcik, Jitka Vesela, Hana Remešová, Michaela Dostalova Merkerova, Andrea Hrustincova, Nikoleta Loudova, Anna Jonasova
Publikováno v:
Blood. 132:5496-5496
INTRODUCTION: Myelodysplastic syndromes (MDS) represent a heterogeneous spectrum of hematopoietic stem cell disorders characterized by inefficient hematopoiesis, peripheral blood cytopenia, dysplasia in one or more myeloid cell lineages, and a tenden