Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hana Raschmanová"'
Autor:
Hana Raschmanová, Iwo Zamora, Martina Borčinová, Patrick Meier, Astrid Weninger, Dominik Mächler, Anton Glieder, Karel Melzoch, Zdeněk Knejzlík, Karin Kovar
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Pichia pastoris (Komagataella sp.) is broadly used for the production of secreted recombinant proteins. Due to the high rate of protein production, incorrectly folded proteins may accumulate in the endoplasmic reticulum (ER). To restore their proper
Externí odkaz:
https://doaj.org/article/289591b63495445b82e537f21870a2e8
Publikováno v:
Applied Microbiology and Biotechnology
Abstract Folding and processing of proteins in the endoplasmic reticulum (ER) are major impediments in the production and secretion of proteins from Pichia pastoris (Komagataella sp.). Overexpression of recombinant genes can overwhelm the innate secr
Autor:
Hana Raschmanová, Katerina Jureckova, Ivo Provaznik, Barbora Branska, Karel Sedlar, Maryna Vasylkivska, Petra Patakova
Publikováno v:
Applied Microbiology and Biotechnology. 105:877-889
Pumping toxic substances through a cytoplasmic membrane by protein transporters known as efflux pumps represents one bacterial mechanism involved in the stress response to the presence of toxic compounds. The active efflux might also take part in exp
Autor:
Katerina Jureckova, Karel Sedlar, Ivo Provaznik, Jan Kolek, Maryna Vasylkivska, Hana Raschmanová, Barbora Branska, Petra Patakova
Publikováno v:
Frontiers in Microbiology. 2021, vol. 12, issue 1, p. 1-10.
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
Gene expression analysis through reverse transcription-quantitative real-time polymerase chain reaction (RT-qPCR) depends on correct data normalization by reference genes with stable expression. Although Clostridium beijerinckii NRRL B-598 is a promi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eded494fbc3b3b2810c443778bdff561
https://hdl.handle.net/11012/196506
https://hdl.handle.net/11012/196506
Autor:
Iwo Zamora, Helena Marešová, Verena Looser, Martina Borčinová, Karin Kovar, Hana Raschmanová, Sven Hirsch, Pavel Kyslík
Publikováno v:
Applied Microbiology and Biotechnology
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)
To take full advantage of recombinant Pichia pastoris (Komagataella phaffii) as a production system for heterologous proteins, the complex protein secretory proce
To take full advantage of recombinant Pichia pastoris (Komagataella phaffii) as a production system for heterologous proteins, the complex protein secretory proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9378c7a5774a056595b574164e7073
Autor:
Zdeněk Knejzlík, Hana Raschmanová, Karel Melzoch, Leona Paulova, Karin Kovar, Barbora Branska
Publikováno v:
Folia Microbiologica. 63:773-787
Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch) Pharmaceutical grade trypsin is in ever-increasing demand for medical and industrial applications. Improving the efficiency of existing biotechnological manufacturing
Publikováno v:
Biotechnology advances. 36(3)
Within five years, the CRISPR-Cas system has emerged as the dominating tool for genome engineering, while also changing the speed and efficiency of metabolic engineering in conventional (Saccharomyces cerevisiae and Schizosaccharomyces pombe) and non