Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Hana M. Dobrovolny"'
Autor:
Zakarya Noffel, Hana M. Dobrovolny
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 7, Pp 12666-12681 (2023)
Defective viral genomes (DVGs) are viral genomes that contain only a partial viral RNA and so cannot replicate within cells on their own. If a cell containing DVGs is subsequently infected with a complete viral genome, the DVG can then use the missin
Externí odkaz:
https://doaj.org/article/23fdf89935fe499eb6a036d083112751
Autor:
Paul Alexander, Hana M. Dobrovolny
Publikováno v:
Epidemiologia, Vol 3, Iss 1, Pp 81-96 (2022)
With the advent of rapid multiplex PCR, physicians have been able to test for multiple viral pathogens when a patient presents with influenza-like illness. This has led to the discovery that many respiratory infections are caused by more than one vir
Externí odkaz:
https://doaj.org/article/3c8188cdc2994032b938e13cbbbb5df5
Autor:
Ela Guo, Hana M. Dobrovolny
Publikováno v:
Viruses, Vol 15, Iss 9, p 1812 (2023)
Oncolytic adenoviruses (OAds) present a promising path for cancer treatment due to their selectivity in infecting and lysing tumor cells and their ability to stimulate the immune response. In this study, we use an ordinary differential equation (ODE)
Externí odkaz:
https://doaj.org/article/8d2cd4ed9c7a43379d8a251eb87d20bb
Autor:
Binaya Tuladhar, Hana M. Dobrovolny
Publikováno v:
AIMS Mathematics, Vol 5, Iss 1, Pp 140-157 (2020)
Mathematical models of the electrical response of cardiac cells are used to help develop an understanding of the electrophysiological properties of cardiac cells. Increasingly complex models are being developed in an effort to enhance the biological
Externí odkaz:
https://doaj.org/article/a097f55c6a4542859a0a843c5821119f
Autor:
Lubna Pinky, Hana M. Dobrovolny
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Some viruses have the ability to block or suppress growth of other viruses when simultaneously present in the same host. This type of viral interference or viral block has been suggested as a potential interaction between some respiratory viruses inc
Externí odkaz:
https://doaj.org/article/ea965a56721e443086e6da7a76badf21
Autor:
Thalia Rodriguez, Hana M. Dobrovolny
Publikováno v:
Royal Society Open Science, Vol 8, Iss 11 (2021)
The SARS-CoV-2 virus disproportionately causes serious illness and death in older individuals. In order to have the greatest impact in decreasing the human toll caused by the virus, antiviral treatment should be targeted to older patients. For this,
Externí odkaz:
https://doaj.org/article/20c7dc48ce8b420aaa775f6742076300
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Respiratory viral infections are a leading cause of mortality worldwide. As many as 40% of patients hospitalized with influenza-like illness are reported to be infected with more than one type of virus. However, it is not clear wh
Externí odkaz:
https://doaj.org/article/95b515e9980d4fccb8c5da33e3cf9d53
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Combination therapy for influenza can have several benefits, from reducing the emergence of drug resistant virus strains to decreasing the cost of antivirals. However, there are currently only two classes of antivirals approved for use against influe
Externí odkaz:
https://doaj.org/article/c2bb9891fc15436a99d3649ee2d73af4
A comparison of RSV and influenza in vitro kinetic parameters reveals differences in infecting time.
Autor:
Gilberto Gonzàlez-Parra, Filip De Ridder, Dymphy Huntjens, Dirk Roymans, Gabriela Ispas, Hana M Dobrovolny
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192645 (2018)
Influenza and respiratory syncytial virus (RSV) cause acute infections of the respiratory tract. Since the viruses both cause illnesses with similar symptoms, researchers often try to apply knowledge gleaned from study of one virus to the other virus
Externí odkaz:
https://doaj.org/article/b927870f2a4b43049fc16250aee81f64
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180582 (2017)
The emergence of influenza drug resistance has become of particular interest as current planning for an influenza pandemic involves using massive amounts of antiviral drugs. We use semi-stochastic simulations to examine the emergence of drug resistan
Externí odkaz:
https://doaj.org/article/282515ab2b764df7ba0118d7e374ed1b