Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hana M Odeh"'
Autor:
Conrad David Valdez, Joanne N Davis, Hana M Odeh, Tristan L Layfield, Craig S Cousineau, Thomas R Berton, David G Johnson, Kirk J Wojno, Mark L Day
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25187 (2011)
Although androgen receptor (AR) function has been extensively studied, regulation of the AR gene itself has been much less characterized. In this study, we observed a dramatic reduction in the expression of androgen receptor mRNA and protein in hyper
Externí odkaz:
https://doaj.org/article/e6ae3e96e5ce42f8a4995a97a0d19a50
Publikováno v:
Chemical Reviews.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4688d79daf0c8548224bbbff054c051
https://doi.org/10.1021/acs.chemrev.2c00851
https://doi.org/10.1021/acs.chemrev.2c00851
Autor:
Rubika Balendra, Igor Ruiz de los Mozos, Idoia Glaria, Carmelo Milioto, Hana M Odeh, Katherine M Wilson, Agnieszka M Ule, Martina Hallegger, Laura Masino, Stephen Martin, Rickie Patani, James Shorter, Jernej Ule, Adrian M Isaacs
An intronic GGGGCC repeat expansion inC9orf72is a common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. The repeats are transcribed in both sense and antisense directions to generate distinct dipeptide repeat proteins, of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7884474e238fa34edd2e211aa5ecae20
https://doi.org/10.1101/2022.10.10.511318
https://doi.org/10.1101/2022.10.10.511318
Autor:
Hana M. Odeh, James Shorter
Publikováno v:
Emerg Top Life Sci
A hexanucleotide repeat expansion GGGGCC (G4C2) within chromosome 9 open reading frame 72 (C9orf72) is the most common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). This seminal realization has rapidly focus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fda9a146c92e19292b5805454658c6a
https://doi.org/10.1042/etls20190167
https://doi.org/10.1042/etls20190167
Autor:
James Shorter, Hana M. Odeh
Publikováno v:
Neuron
The most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is a hexanucleotide repeat expansion in C9orf72 (C9-HRE). While RNA and dipeptide repeats produced by the C9-HRE disrupt nucleocytoplasmic transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd306c52b45364bce395a2bb8ae67d95
https://doi.org/10.1016/j.neuron.2020.03.017
https://doi.org/10.1016/j.neuron.2020.03.017
Autor:
Hana M. Odeh, Martina Hallegger, Aram G. Amalietti, Bo Lim Lee, Bede Portz, Nicholas M. Luscombe, Klara Kuret, Jack D. Rubien, James Shorter, Frédérique Rau, Nicolas L. Fawzi, Rickie Patani, Ina Huppertz, Jernej Ule, Katie E. Copley, Anob M. Chakrabarti, Flora C.Y. Lee
Publikováno v:
Cell, vol. 184, no. 18, pp. 4680-4696,e1-e22, 2021.
Cell
Cell
Summary Mutations causing amyotrophic lateral sclerosis (ALS) often affect the condensation properties of RNA-binding proteins (RBPs). However, the role of RBP condensation in the specificity and function of protein-RNA complexes remains unclear. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ed2633fd10b3a00dd40befabec71e0
https://dirros.openscience.si/Dokument.php?id=18781&dn=
https://dirros.openscience.si/Dokument.php?id=18781&dn=
Publikováno v:
J Mol Biol
Nuclear-import receptors (NIRs) engage nuclear-localization signals (NLSs) of polypeptides in the cytoplasm and transport these cargo across the size-selective barrier of the nuclear-pore complex into the nucleoplasm. Beyond this canonical role in nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231c2c49784734a3f8820fd70d907d91
https://europepmc.org/articles/PMC8748273/
https://europepmc.org/articles/PMC8748273/
Autor:
Aaron D. Gitler, Nicholas J. Brandon, Korrie L. Mack, Hana M. Odeh, Thomas A. Ollerhead, Bo Lim Lee, Stephen J. Moss, Bradley Class, Ashkan Javaherian, James Shorter, John Dunlop, Alice Flynn Ford, Mari Aikio, Steven Finkbeiner, Heike J. Wobst, Ryan R. Cupo, Lauren E. Drake, Dean G. Brown, Ashmita Baral, Nicholas A. Castello, Edward M. Barbieri
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder typically characterized by insoluble inclusions of hyperphosphorylated TDP-43. The mechanisms underlying toxic TDP-43 accumulation are not understood. Persistent activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61a033b9c4422f431aa9088ab9b0181b
https://doi.org/10.1101/2021.08.04.455154
https://doi.org/10.1101/2021.08.04.455154
Autor:
Hana M. Odeh, James Shorter
Publikováno v:
Nature. 601:29-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c0f3c7a7c017e9ea9fc669def5e618
https://doi.org/10.1038/d41586-021-03605-0
https://doi.org/10.1038/d41586-021-03605-0
Autor:
Dorothee Dormann, James Shorter, Francesca Simonetti, Marian Hruska-Plochan, Sinem Usluer, Hana M. Odeh, Charlotte M. Fare, Tobias Madl, Dieter Edbauer, Mario Hofweber, Magdalini Polymenidou, Mareike Czuppa, Benjamin Bourgeois, Saskia Hutten
Publikováno v:
Cell reports
Cell reports 33(12), 108538 (2020). doi:10.1016/j.celrep.2020.108538
Cell reports 33(12), 108538 (2020). doi:10.1016/j.celrep.2020.108538
SUMMARY Nuclear import receptors, also called importins, mediate nuclear import of proteins and chaperone aggregation-prone cargoes (e.g., neurodegeneration-linked RNA-binding proteins [RBPs]) in the cytoplasm. Importins were identified as modulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f215b36a8bdac9b075423fd7758cb8
https://www.zora.uzh.ch/id/eprint/197563/
https://www.zora.uzh.ch/id/eprint/197563/