Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hana Fakim"'
Autor:
Tamiko Nishimura, Zoya Padamsi, Hana Fakim, Simon Milette, Wade H. Dunham, Anne-Claude Gingras, Marc R. Fabian
Publikováno v:
Cell Reports, Vol 11, Iss 9, Pp 1425-1436 (2015)
Eukaryotic mRNA degradation often initiates with the recruitment of the CCR4-NOT deadenylase complex and decay factors to the mRNA 3′ terminus. How the 3′-proximal decay machinery interacts with the 5′-terminal cap structure in order to engende
Externí odkaz:
https://doaj.org/article/dc837888b7fd488ba21070533cca1acb
Publikováno v:
Nucleic Acids Research. 50:7623-7636
Processing bodies (P-bodies) are ribonucleoprotein granules that contain mRNAs, RNA-binding proteins and effectors of mRNA turnover. While P-bodies have been reported to contain translationally repressed mRNAs, a causative role for P-bodies in regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::385b2b39321e70ebbacac9c29a1d152c
https://doi.org/10.1093/nar/gkac557
https://doi.org/10.1093/nar/gkac557
Autor:
Hana Fakim, Christine Vande Velde
Publikováno v:
Seminars in Cell & Developmental Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b366accf8fa009031e5b7e4b1d6dc4c
https://doi.org/10.1016/j.semcdb.2023.05.006
https://doi.org/10.1016/j.semcdb.2023.05.006
Autor:
Eric Bareke, Ze'ev Melamed, Laurie Destroimaisons, Lorne Zinman, Geneviève Di Tomasso, Elizabeth M. H. Tank, Martine Tétreault, Pascale Legault, Anaïs Aulas, Jade-Emmanuelle Deshaies, Sami J. Barmada, Shangxi Xiao, J. Alex Parker, Janice Robertson, Hana Fakim, Christine Vande Velde, Hadjara Sidibé, Paul M. McKeever, Nicolás B. Gómez, Yousra Khalfallah
Publikováno v:
Brain
TDP-43 nuclear depletion and concurrent cytoplasmic accumulation in vulnerable neurons is a hallmark feature of progressive neurodegenerative proteinopathies such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Cellular stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492a2a74325fd31df4145b13e88f6ded
http://europepmc.org/articles/PMC8677511
http://europepmc.org/articles/PMC8677511
Autor:
Marc R. Fabian, Hana Fakim
Publikováno v:
Methods in Molecular Biology ISBN: 9781071609347
Experiments in cell cultures have been useful for investigating a number of RNA endonucleases. However, endonuclease decay intermediates are often challenging to study in cellulo, as decay intermediates are rapidly degraded by exoribonucleases. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afdfd73608363c82549b4c833810c64f
https://doi.org/10.1007/978-1-0716-0935-4_21
https://doi.org/10.1007/978-1-0716-0935-4_21
Autor:
Hana, Fakim, Marc R, Fabian
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2209
Experiments in cell cultures have been useful for investigating a number of RNA endonucleases. However, endonuclease decay intermediates are often challenging to study in cellulo, as decay intermediates are rapidly degraded by exoribonucleases. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b738179cea2dddf3ba178a720b99e6d
https://pubmed.ncbi.nlm.nih.gov/33201479
https://pubmed.ncbi.nlm.nih.gov/33201479
Autor:
Masoumeh Ahmadi, Leana Rosanelli, Vicky Lutchman, Mahdi Heshmati-Moghaddam, Anna Leonov, Asimah Hussain, Vladimir I. Titorenko, Anthony Arlia-Ciommo, Rachel Feldman, Negar Roofigari-Esfahani, Sarah Elsaser, Harshvardhan Rajen, Amanda Piano, Sandra Orfali, Hana Fakim
Publikováno v:
Oncotarget
// Anna Leonov 1 , Rachel Feldman 1 , Amanda Piano 1 , Anthony Arlia-Ciommo 1 , Vicky Lutchman 1 , Masoumeh Ahmadi 1 , Sarah Elsaser 1 , Hana Fakim 1 , Mahdi Heshmati-Moghaddam 1 , Asimah Hussain 1 , Sandra Orfali 1 , Harshvardhan Rajen 1 , Negar Roo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4eff761d9fc61c6ad3a28f7dbf016e
http://europepmc.org/articles/PMC5642482
http://europepmc.org/articles/PMC5642482
Autor:
Hana, Fakim, Marc R, Fabian
Publikováno v:
Advances in experimental medicine and biology. 1203
Most eukaryotic mRNAs maintain a 5' cap structure and 3' poly(A) tail, cis-acting elements that are often separated by thousands of nucleotides. Nevertheless, multiple paradigms exist where mRNA 5' and 3' termini interact with each other in order to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c4a0df011cbac89a040e21736e9d578
https://pubmed.ncbi.nlm.nih.gov/31811634
https://pubmed.ncbi.nlm.nih.gov/31811634
Autor:
Marc R. Fabian, Hana Fakim
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030314330
Most eukaryotic mRNAs maintain a 5' cap structure and 3' poly(A) tail, cis-acting elements that are often separated by thousands of nucleotides. Nevertheless, multiple paradigms exist where mRNA 5' and 3' termini interact with each other in order to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::789fc72f25cd88b469f528348ac14ccc
https://doi.org/10.1007/978-3-030-31434-7_6
https://doi.org/10.1007/978-3-030-31434-7_6
Autor:
Marc R. Fabian, Anne-Claude Gingras, Tobias Brandmann, Zoya Padamsi, Ji-Young Youn, Hana Fakim, Martin Jinek
Publikováno v:
The EMBO Journal. 37
The LSM domain-containing protein LSM14/Rap55 plays a role in mRNA decapping, translational repression, and RNA granule (P-body) assembly. How LSM14 interacts with the mRNA silencing machinery, including the eIF4E-binding protein 4E-T and the DEAD-bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd03eaa98541ef146fc89908023c59b
https://doi.org/10.15252/embj.201797869
https://doi.org/10.15252/embj.201797869