Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hana Šváchová"'
Publikováno v:
British Journal of Haematology. 163:551-564
Multiple myeloma (MM) is a haematological malignancy characterized by the accumulation of clonal plasma cells (PCs) in the bone marrow (BM). Although novel therapeutic strategies have prolonged survival of patients, the disease remains difficult to t
Autor:
Roman Hájek, Petra Kaisarova, Tomas Pika, Martina Almáši, Miroslav Penka, Vladimir Maisnar, Sabina Ševčíková, Ludek Pour, Hana Šváchová, Ondrej Slaby, Jakub Radocha, Vlastimil Scudla
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 11:414-420
Introduction/Background Venous thromboembolism (VTE), with the subsequent risk of pulmonary embolism, is a common adverse effect of thalidomide treatment in patients with multiple myeloma (MM). In our retrospective study, we analyzed candidate single
Autor:
Lucie Burešová, Tomáš Büchler, Zuzana Mikulková, Luděk Pour, Hana Šváchová, Jiří Vorlíček, Zdeněk Adam, L. Kovarova, Miroslav Penka, Roman Hájek
Publikováno v:
Neoplasma. 57:29-34
Our aim was to establish whether the pretreatment levels of angiogenesis activators and inhibitors can be used to predict clinical responses to treatment that included high-dose chemotherapy with peripheral stem cell support.br /We analyzed samples a
Autor:
Hana Šváchová, Pavel Nemec, L. Kovarova, Zdenek Adam, Miroslav Penka, Ludek Pour, Lucie Burešová, Martina Almáši, Roman Hájek, Tomas Buchler, Jiri Vorlicek
Publikováno v:
Annals of Hematology
Annals of Hematology, Springer Verlag, 2009, 89 (4), pp.385-389. ⟨10.1007/s00277-009-0834-3⟩
Annals of Hematology, Springer Verlag, 2009, 89 (4), pp.385-389. ⟨10.1007/s00277-009-0834-3⟩
International audience; Angiogenesis plays a significant role in the pathogenesis of multiple myeloma (MM). We have measured concentrations of angiogenesis activators, including vascular endothelial growth factor (VEGF), basic fibroblast growth facto
Autor:
Jiri Jarkovsky, Fedor Kryukov, Katerina Gracova, Lenka Besse, Roman Hájek, Tomas Jelinek, Lenka Zahradová, Hana Šváchová, Lucie Rihova
Publikováno v:
Blood. 128:5608-5608
Background:Neural stem cell marker nestin is a suitable diagnostic and prognostic indicator of malignancy and potential cancer stem cells marker in solid tumors. Currently, nestin has been demonstrated as an epithelial-to-mesenchymal transition relat
Autor:
Roman Hájek, Lucie Rihova, Hana Šváchová, Elena Kryukova, Pavel Nemec, Fedor Kryukov, Lenka Kubiczková, Henrieta Grešliková, Sabina Ševčíková
Publikováno v:
British Journal of Haematology; Vol 164
The stem cell marker nestin (NES) is found in dividing cells of developing and regenerating tissues. Upon terminal differentiation, NES expression is diminished but may be re-expressed following injury or in cancer. Surprisingly, we recently confirme
Publikováno v:
Multiple Myeloma-A Quick Reflection on the Fast Progress
Modern molecular and cytogenetic approaches have furthered progress in our understanding of MM biology and have led to the development of targeted therapy that has improved management of this incurable disease. Novel agents such as bortezomib, lenali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df271d63afe20e6ec398454657f01153
http://www.intechopen.com/articles/show/title/heterogeneity-and-plasticity-of-multiple-myeloma
http://www.intechopen.com/articles/show/title/heterogeneity-and-plasticity-of-multiple-myeloma
Autor:
Jana Štossová, Elena Vladimirovna Dementyeva, L. Kovarova, Fedor Kryukov, Jana Čumová, Sabina Ševčíková, Roman Hájek, Ivana Burešová, Hana Šváchová
Publikováno v:
Clinical chemistry and laboratory medicine. 50(6)
Monoclonal gammopathy is characterized by the presence of monoclonal immunoglobulin which is produced by a specifi c clone of terminally differentiated long-living plasma cells (PC) in the bone marrow. More detailed understanding of this clone at the
Publikováno v:
Leukemia research. 35(8)
Nestin is considered to be a characteristic marker of multipotent proliferative precursors found in some embryonic and fetal tissues. Its expression might be a suitable diagnostic and prognostic indicator of malignancy and a potential marker of cance
Autor:
Jakub Neradil, Jirina Relichova, Renata Veselská, Pavel Cejpek, Petr Kuglík, Hana Šváchová, Tomáš Loja
Publikováno v:
BMC Cancer, Vol 6, Iss 1, p 32 (2006)
BMC Cancer
BMC Cancer
Background Nestin is a protein belonging to class VI of intermediate filaments that is produced in stem/progenitor cells in the mammalian CNS during development and is consecutively replaced by other intermediate filament proteins (neurofilaments, GF