Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hana Štambergová"'
Publikováno v:
The FASEB Journal
Hexose-6-phosphate dehydrogenase (H6PD) produces reduced NADPH in the endoplasmic reticulum (ER) lumen. NADPH constitutes a cofactor for many reducing enzymes, and its inability to traverse biologic membranes makes in situ synthesis of NADPH in the E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e40e1f74313e6e934309178e62eba2ca
https://doi.org/10.1096/fj.201700870rr
https://doi.org/10.1096/fj.201700870rr
Autor:
Hana Štambergová, Lucie Zemanová, Jana Havrankova, Miroslav Šafr, Tereza Lundová, Markéta Preininger Svobodová, Vladimír Wsól
Publikováno v:
Molecular and Cellular Biochemistry. 411:35-42
Dehydrogenase/reductase (SDR family) member 8 (DHRS8, SDR16C2) belongs to the short-chain dehydrogenase/reductase (SDR) superfamily, one of the largest enzyme groups. In addition to the well-known members which participate in the metabolism of import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ed8d41c850bf1727e40a41987755e9
https://doi.org/10.1007/s11010-015-2566-0
https://doi.org/10.1007/s11010-015-2566-0
Autor:
Adam Skarka, Lucie Zemanová, Miroslav Šafr, Hana Štambergová, Beata Malčeková, Vladimír Wsól, Jana Havrankova, Tereza Lundová
Publikováno v:
Chemico-Biological Interactions. 234:178-187
Dehydrogenase/reductase (SDR family) member 3 (DHRS3), also known as retinal short-chain dehydrogenase/reductase (retSDR1) is a member of SDR16C family. This family is thought to be NADP(H) dependent and to have multiple substrates; however, to date,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4321f6ec6545a296cd7e0726e1206fe0
https://doi.org/10.1016/j.cbi.2014.10.018
https://doi.org/10.1016/j.cbi.2014.10.018
Publikováno v:
Protein Expression and Purification. 95:44-49
Dehydrogenase/reductase SDR family member 7 (DHRS7, SDR34C1, retSDR4) is one of the many endoplasmic reticulum bound members of the SDR superfamily. Preliminary results indicate its potential significance in human metabolism. DHRS7 containing TEV-cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7a5670e3ceb53728259907792148bc
https://doi.org/10.1016/j.pep.2013.11.013
https://doi.org/10.1016/j.pep.2013.11.013
Publikováno v:
Chemico-Biological Interactions. 207:52-57
Dehydrogenase/reductase (SDR family) member 7 (DHRS7, retSDR4, SDR34C1) is a previously uncharacterized member of the short-chain dehydrogenase/reductase (SDR) superfamily. While human SDR members are known to play an important role in various (patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac9ffd99906163e1935821af5d61d01
https://doi.org/10.1016/j.cbi.2013.11.003
https://doi.org/10.1016/j.cbi.2013.11.003
Publikováno v:
International journal of biological macromolecules. 105(Pt 1)
Human DHRS7 (SDR34C1) is one of insufficiently described enzymes of the short-chain dehydrogenase/reductase superfamily. The members of this superfamily often play an important pato/physiological role in the human body, participating in the metabolis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbc4451ff8d6a6df18b1ac708fd8467
https://pubmed.ncbi.nlm.nih.gov/28687384
https://pubmed.ncbi.nlm.nih.gov/28687384
Autor:
Hana Štambergová, Rudolf Andrýs, Vladimír Wsól, Lucie Skarydova, Lucie Holubova, Jana Kňavová, Zuzana Bílková
Publikováno v:
Journal of Separation Science. 36:1176-1184
Carbonyl-reducing enzymes are important in both metabolism of endogenous substances and biotransformation of xenobiotics. Because sufficient amounts of native enzymes must be obtained to study their roles in metabolism, an efficient purification stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b27d19b98024b044c9e91e7f117c71c
https://doi.org/10.1002/jssc.201201141
https://doi.org/10.1002/jssc.201201141
Publikováno v:
Drug Metabolism Letters. 6:174-181
Tobacco smoking is the most widely known cause of human cancer-related death worldwide. NNK is one of the proved human carcinogens contributing to the development of several types of cancer. The carcinogenic effect of NNK depends on the metabolic pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679ca0be8da574ff5e2fe277ef8d1e82
https://doi.org/10.2174/1872312811206030004
https://doi.org/10.2174/1872312811206030004
Publikováno v:
Chemico-Biological Interactions. 191:66-74
Anthracyclines (ANTs) are widely used in the treatment of various forms of cancer. Although their usage contributes to an improvement in life expectancy, it is limited by severe adverse effects-acute and chronic cardiotoxicity. Several enzymes from b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd655060fdf74251b525c04f97ace5a
https://doi.org/10.1016/j.cbi.2010.12.016
https://doi.org/10.1016/j.cbi.2010.12.016
Autor:
Adam Skarka, Hana Štambergová, Beata Malčeková, Vladimír Wsól, Tereza Lundová, Lucie Zemanová, Miroslav Šafr
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 155
The metabolism of steroids and retinoids has been studied in detail for a long time, as these compounds are involved in a broad spectrum of physiological processes. Many enzymes participating in the conversion of such compounds are members of the sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80327991250bfc067be29a37982acdcb
https://pubmed.ncbi.nlm.nih.gov/26466768
https://pubmed.ncbi.nlm.nih.gov/26466768