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Unilateral 6-Hydroxydopamine-Lesioned Rat as Relevant Model to Study the Pain Related to Parkinson’s Disease

Autor: Imed Messaoudi, Ameni Nsibi, Hana Saoud, Nour Elhouda Saidi, Sahar Mani

Publikováno v: Neurology and Neurobiology. :1-5

The present study was conducted to test the use of the hemiparkinsonian rat, obtained by the unilateral injection of 6-hydroxydopamine (6-OHDA) in the substantia nigra pars compacta (SNc), as a suitable model for the study of pain associated to Parki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::507c3f79afbd3aea7d09151382d6cf4e
https://doi.org/10.31487/j.nnb.2019.04.03

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Association of VEGF-A and KDR polymorphisms with the development of schizophrenia

Autor: Hana Saoud, Youssef Aflouk, Amira Ben Afia, Lotfi Gaha, Besma Bel Hadj Jrad

Publikováno v: Human immunology. 83(6)

Several approaches indicate different blood flow disturbances in schizophrenia. VEGF-A is widely recognized as one of the key molecules involved in the angiogenesis process through mainly its receptor KDR. The current work was designed to investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e75dd54d564707b42e0d0222211fcc
https://pubmed.ncbi.nlm.nih.gov/35428537

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Association of VEGF and KDR polymorphisms with the development of schizophrenia

Autor: Amira Ben Afia, Lotfi Gaha, Besma Bel Hadj Jrad, Hana Saoud, Youssef Aflouk

AimSeveral approaches indicate different blood flow disturbances in schizophrenia (Scz). Vascular endothelial growth factor (VEGF) is widely recognized as one of the key molecules implicated in the angiogenesis process through mainly its receptor KDR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bab5b6ac3cf80aa52787c1c54426a155
https://doi.org/10.1101/2021.08.06.21261566

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Association between TLR2 polymorphisms (- 196-174 Ins/Del, R677W, R753Q, and P631H) and schizophrenia in a Tunisian population

Autor: Besma Bel Hadj Jrad, Hana Saoud, Oumaima Inoubli, Lotfi Gaha, Ferid Zaafrane, Youssef Aflouk

Publikováno v: Immunologic research. 69(6)

Since immune dysregulation has been well studied in schizophrenia pathophysiology, recent studies showed a potent role of TLR2 in neuroinflammation process underlying schizophrenia pathogenesis. However, the genetic predisposition is still unclear. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd7560c184566bd3dcf4fda484f2e8c
https://pubmed.ncbi.nlm.nih.gov/34546527

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MK-801-induced behavioral and dopaminergic responses in the shell part of the nucleus accumbens in adult rats are disrupted after neonatal blockade of the ventral subiculum

Autor: E. Kereselidze, Hana Saoud, Alain Louilot, Séverine Eybrard

The present study was conducted in the context of animal modeling of schizophrenia. It investigated in adult rats, after transient neonatal blockade of the ventral subiculum (VSub), the impact of a very specific non-competitive antagonist of NMDA rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650f3154d922cc5f6a206062427215a9
https://doi.org/10.1101/2021.02.16.431488

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Inteurleukin-8 gene variations and the susceptibility to schizophrenia

Autor: Youssef Aflouk, Hana Saoud, Lotfi Gaha, Amira Ben Afia, Besma Bel Hadj Jrad, Farid Zaafrane

Publikováno v: Psychiatry research. 293

The relevance of Interleukin-8 (IL-8) cytokine alteration in the peripheral and central system has been widely shown in psychosis while variation in the IL-8 gene remains largely unexplored and to the best of our knowledge, IL-8 polymorphisms have ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d5a2c6913bfdf7ec02cedf430c7908
https://pubmed.ncbi.nlm.nih.gov/32920525

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Postnatal functional inactivation of the ventral subiculum enhances dopaminergic responses in the core part of the nucleus accumbens following ketamine injection in adult rats

Autor: Séverine Eybrard, Hana Saoud, Alain Louilot, Duco De Beus

Publikováno v: Neurochemistry International
Neurochemistry International, Elsevier, 2020, 137, pp.104736. ⟨10.1016/j.neuint.2020.104736⟩
Neurochemistry International, 2020, 137, pp.104736. ⟨10.1016/j.neuint.2020.104736⟩

For almost two decades schizophrenia has been considered to be a functional disconnection disorder. This functional disconnectivity between several brain regions could have a neurodevelopmental origin. Various approaches suggest the ventral subiculum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11b718bc76a55dcd6a53787f6f49be4b
https://hal.archives-ouvertes.fr/hal-02913173v2/file/pagination_NCI_104736-2.pdf

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MK-801-induced behavioral and dopaminergic responses in the shell part of the nucleus accumbens in adult male rats are disrupted after neonatal blockade of the ventral subiculum

Autor: Elora Kereselidze, Hana Saoud, Alain Louilot, Séverine Eybrard

Publikováno v: Neurochemistry International
Neurochemistry International, Elsevier, 2021, Volume 150, pp.105195. ⟨10.1016/j.neuint.2021.105195⟩

International audience; The present study was conducted in the context of animal modeling of schizophrenia. It investigated in adult male rats, after transient neonatal blockade of the ventral subiculum (VSub), the impact of a very specific non-compe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1bb5d2c80a931b663fd5f0b2774290
https://doi.org/10.1016/j.neuint.2021.105195

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