Výsledky vyhledávání - "Han-yan Yang"

Akademický článek

Antiplatelet and Antithrombotic Effects of Isaridin E Isolated from the Marine-Derived Fungus via Downregulating the PI3K/Akt Signaling Pathway

Autor: Ni Pan, Zi-Cheng Li, Zhi-Hong Li, Sen-Hua Chen, Ming-Hua Jiang, Han-Yan Yang, Yao-Sheng Liu, Rui Hu, Yu-Wei Zeng, Le-Hui Dai, Lan Liu, Guan-Lei Wang

Publikováno v: Marine Drugs, Vol 20, Iss 1, p 23 (2021)

Isaridin E, a cyclodepsipeptide isolated from the marine-derived fungus Amphichorda felina (syn. Beauveria felina) SYSU-MS7908, has been demonstrated to possess anti-inflammatory and insecticidal activities. Here, we first found that isaridin E conce

Externí odkaz: https://doaj.org/article/633ca58a1aa945c4862d1fc279508b43

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Platelet CFTR inhibition enhances arterial thrombosis via increasing intracellular Cl− concentration and activation of SGK1 signaling pathway

Publikováno v: Acta Pharmacologica Sinica. 43:2596-2608

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::adb48b1d968b1fd0aa2472a558fa4135
https://doi.org/10.1038/s41401-022-00868-9

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Platelet CFTR inhibition enhances arterial thrombosis via increasing intracellular Cl

Publikováno v: Acta pharmacologica Sinica. 43(10)

Platelet hyperactivity is essential for thrombus formation in coronary artery diseases (CAD). Dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) in patients with cystic fibrosis elevates intracellular Cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f41a8fd33bdcb0712bc668565e9f85e1
https://pubmed.ncbi.nlm.nih.gov/35241769

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CFTR Suppresses Neointimal Formation Through Attenuating Proliferation and Migration of Aortic Smooth Muscle Cells

Autor: Liu-Yi Lu, Ni Pan, Ze-Han Huang, Jing-Song Wang, Yong-Bo Tang, Hong-Shuo Sun, Hui Han, Han-Yan Yang, Jun-Zhen Zhu, Yong-Yuan Guan, Bin Zhang, Dong-Zhi Li, Guan-Lei Wang

Publikováno v: Journal of cardiovascular pharmacology. 79(6)

Cystic fibrosis transmembrane conductance regulator (CFTR) plays important roles in arterial functions and the fate of cells. To further understand its function in vascular remodeling, we examined whether CFTR directly regulates platelet-derived grow

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbad11393d292978df25d2508b4f76d
https://pubmed.ncbi.nlm.nih.gov/35266910

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Effect of short-term acumagnetotherapy on diabetic kidney disease in patients with type II diabetes and study on the molecular mechanism

Autor: Zi-yu Zhou, Ji-zhang Liu, Li-wei Ren, Ke-dan Chu, Jian-ping Weng, Han-yan Yang, Zhi-wen Yu

Publikováno v: World Journal of Acupuncture - Moxibustion. 25:1-10

Objective To explore whether magnetotherapy is preventive in retarding diabetic kidney disease (DKD) progression and investigate underling molecular mechanisms related to its therapeutic efficacy. Methods Twenty-eight patients with type II diabetes (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::376b8fb0b4ebeac00ef9e587c9795ad9
https://doi.org/10.1016/s1003-5257(15)30056-8

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Curcumin Attenuates Urinary Excretion of Albumin in Type II Diabetic Patients with Enhancing Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) System and Repressing Inflammatory Signaling Efficacies

Autor: Z. Yu, Jun Liu, Xinchun Li, Lin Chen, Han-yan Yang, Jianping Weng, Zi-yu Zhou, Wen Xu

Publikováno v: Experimental and Clinical Endocrinology & Diabetes. 123:360-367

Curcumin has a therapeutic potential in treating diabetic kidney disease (DKD) while potential mechanisms underlining this beneficial effect remain to be elucidated. In the present study, curcumin intervention was performed in patients with Type II d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717506616a22a01587b892727a1dba8c
https://doi.org/10.1055/s-0035-1545345

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Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signaling

Autor: Zhiwen Yu, Zi-yu Zhou, Han-yan Yang, Ping Zhan, Li-wei Ren, Dan-dan Chai

Accumulating evidence shows that lipopolysaccharides (LPS) derived from gut gram-negative bacteria can be absorbed, leading to endotoxemia that triggers systemic inflammation and insulin resistance. In this study we examined whether metformin attenua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf16dd4734236b09436f13308d56374
https://europepmc.org/articles/PMC4973377/

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Insulin Increases Sestrin 2 Content by Reducing Its Degradation through the PI3K/mTOR Signaling Pathway

Autor: Han-yan Yang, Dan-dan Chai, Zi-yu Zhou, Guoyu Wang, Zhiwen Yu

Publikováno v: International Journal of Endocrinology, Vol 2015 (2015)
International Journal of Endocrinology

Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068085269b5bbc837c79b53340953440

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