Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Han-sin Lee"'
Autor:
Du Yeon Shin, Jae Suh Park, Han-Sin Lee, Wooyoung Shim, Lauren Jin, Kyo Won Lee, Jae Berm Park, Dong Hyun Kim, Jae Hyeon Kim
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101658- (2024)
Islet transplantation is the most effective treatment strategy for type 1 diabetes. Long-term storage at ultralow temperatures can be used to prepare sufficient islets of good quality for transplantation. For freezing islets, dimethyl sulfoxide (DMSO
Externí odkaz:
https://doaj.org/article/f76c61789dc14b7d9efba31c787356b3
Autor:
Geun Soo Kim, Chan Woo Cho, Jong Hyun Lee, Du Yeon Shin, Han Sin Lee, Kyo Won Lee, Yeongbeen Kwon, Jae Sung Kim, Heung-Mo Yang, Sung Joo Kim, Jae Berm Park
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Many groups are working to improve the results of clinical allogeneic islet transplantation in a primate model. However, few studies have focused on the optimal islet dose for achieving normal glycemia without exogenous insulin after transpl
Externí odkaz:
https://doaj.org/article/386c95a3a3c44343810ce598f940de59
Autor:
Soo Bin Jang, Sang-Man Jin, Hyung Shik Kim, Yong Yeon Jeong, Sang Jun Lee, Soojung Hahn, Hyemin Lee, Han Sin Lee, Jae Hyeon Kim, Dong Yun Lee
Publikováno v:
Biomaterials. 287
Cell therapy is targeted at many organs, but locally or systemically delivered cells are shortly able to survive resulting from the immune/inflammation reactions and irregular cell targeting. Here we explore the multimodal nanoparticle having anti-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d899019a2104fb6cabcf349699cbf867
https://pubmed.ncbi.nlm.nih.gov/35849998
https://pubmed.ncbi.nlm.nih.gov/35849998
Autor:
Han Sin Lee, Sung Joo Kim, Chan Woo Cho, Geun Soo Kim, Jong Hyun Lee, Jae Sung Kim, Kyo Won Lee, Heung-Mo Yang, Yeongbeen Kwon, Jae Berm Park, Du Yeon Shin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Many groups are working to improve the results of clinical allogeneic islet transplantation in a primate model. However, few studies have focused on the optimal islet dose for achieving normal glycemia without exogenous insulin after transplantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad60d7dd35b2bc95aed9901bd675af42
http://europepmc.org/articles/PMC8060424
http://europepmc.org/articles/PMC8060424
Autor:
Chan Woo Cho, Sung Joo Kim, Han Sin Lee, Heung-Mo Yang, Du Yeon Shin, Geun Soo Kim, Kyo Won Lee, Jong Hyun Lee, Jae Berm Park
Many groups are working to improve the results of clinical allogeneic islet transplantation in a primate model. However, few studies have focused on the optimal islet dose for achieving normal glycemia without exogenous insulin after transplantation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::651e0eb1257a9f17f201f481b6c88999
https://doi.org/10.21203/rs.3.rs-149670/v1
https://doi.org/10.21203/rs.3.rs-149670/v1
Autor:
Bae Jun Oh, Seungyeon Ha, Jae Hyeon Kim, Han Sin Lee, Sang-Man Jin, Youngsang Kwon, Gyuri Kim, Hyunjin Kim
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsREFERENCES. 21(4)
Inhibition of mitochondrial reactive oxygen species (ROS) and subsequent damage-associated molecular patterns (DAMPs)-induced inflammatory responses could be a novel target in clinical islet transplantation. We investigated the protective effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29cd14fa50a13e7aa73ebab77010f22
https://pubmed.ncbi.nlm.nih.gov/32978875
https://pubmed.ncbi.nlm.nih.gov/32978875
Autor:
Du Yeon Shin, Han Sin Lee, Hee Jung Kang, Geun-Soo Kim, Muhammad R. Haque, Yeongbeen Kwon, Jae Berm Park, Sang Hoon Lee, Kyo Won Lee, Hyojun Park, Sung-Joo Kim, Jae Hyeon Kim, Sang-Man Jin, Youngro Byun
Publikováno v:
Biomaterials. 171:164-177
Intraportal pancreatic islet transplantation incurs huge cell losses during its early stages due to instant blood-mediated inflammatory reactions (IBMIRs), which may also drive regulation of the adaptive immune system. Therefore, a method that evades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1db7cfee64353d6bea48ae1fb499010
https://doi.org/10.1016/j.biomaterials.2018.04.028
https://doi.org/10.1016/j.biomaterials.2018.04.028
Autor:
Joon Young Jang, Curie Ahn, Ji Jing Yan, Han Sin Lee, Jung Hwa Ryu, Bohae Kang, Sung Joo Kim, Taishi Fang, Tai Yeon Koo, Jae Ghi Lee, Wook Bin Lee, Jaeseok Yang
Publikováno v:
Transplantation. 102:406-416
Background Macrophages play important roles in xenograft rejection. Here, we investigated whether overexpression of human CD200 or CD47 in porcine endothelial cells (PEC) can suppress macrophages activation in xenogeneic immune responses. Methods PEC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb9099011759c0aab93e133be5e3bd21
https://doi.org/10.1097/tp.0000000000001966
https://doi.org/10.1097/tp.0000000000001966
Autor:
Han Sin Lee, S. J. Kim, Y. S. Chung, S. Hurh, H. Park, Jaeseok Yang, Jae Ghi Lee, Joing Ik Hwang, Jae Berm Park, Curie Ahn, H. J. Yeom, B. Kang, Bumrae Cho
Publikováno v:
American Journal of Transplantation. 16:44-57
Apoptosis during engraftment and inflammation induce poor islet xenograft survival. We aimed to determine whether overexpression of human heme oxygenase-1 (HO-1) or soluble tumor necrosis factor-α receptor type I with human IgG1 Fc (sTNF-αR-Fc) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1fffce2b9f1d93e1dd77fe87c686049
https://doi.org/10.1111/ajt.13467
https://doi.org/10.1111/ajt.13467
Autor:
Hyun-Jin Kim, Gyuri Kim, Jae Hyeon Kim, Youngsang Kwon, Han Sin Lee, Moon-Kyu Lee, Sang-Man Jin
Publikováno v:
Diabetes. 67
Oxidative stress generated during islet isolation, culture, and transplantation causes islet cell damage mediated by hypoxia, reactive oxygen species (ROS) and inflammatory responses. We investigated the protective effects of NecroX-7, a novel ROS sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::513a0678f0f583c7d462f357d0f2ca2e
https://doi.org/10.2337/db18-1744-p
https://doi.org/10.2337/db18-1744-p