Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Han-Gyu Bae"'
Publikováno v:
Genes, Vol 15, Iss 7, p 959 (2024)
Poly(ADP-ribose) polymerase (PARP) inhibitors are targeted therapies that accumulate DNA damage by interfering with DNA repair mechanisms and are approved for treating several cancers with BRCA1/2 mutations. In this study, we utilized CRISPR-dCas9 in
Externí odkaz:
https://doaj.org/article/a5b6c9ff3f4a42f59564066e869eb509
Autor:
Xin Yi Yeo, Woo Ri Chae, Hae Ung Lee, Han-Gyu Bae, Sven Pettersson, Joanes Grandjean, Weiping Han, Sangyong Jung
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTThe complex symbiotic relationship between the mammalian body and gut microbiome plays a critical role in the health outcomes of offspring later in life. The gut microbiome modulates virtually all physiological functions through direct or ind
Externí odkaz:
https://doaj.org/article/85b916025d37430c9faa2329493d30d4
Autor:
Tingxin Zhang, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Han-Gyu Bae, Jumin Xue, Sabeen Wazir, Sara B. Mulinyawe, Jun Hee Kim, Lu O. Sun
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112943- (2023)
Summary: Oligodendrocytes are the sole myelin-producing cells in the central nervous system. Oligodendrocyte number is tightly controlled across diverse brain regions to match local axon type and number, yet the underlying mechanisms remain unclear.
Externí odkaz:
https://doaj.org/article/29cade518a4649ca915ddacd06162a09
Autor:
Yiran Liu, David Castano, Francesco Girolamo, Laia Trigueros-Motos, Han-Gyu Bae, Suat Peng Neo, Jeongah Oh, Pradeep Narayanaswamy, Federico Torta, Kerry Anne Rye, Dong-Gyu Jo, Jayantha Gunaratne, Sangyong Jung, Daniela Virgintino, Roshni R. Singaraja
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 1, Pp 100147- (2022)
The myelin sheath, which is wrapped around axons, is a lipid-enriched structure produced by mature oligodendrocytes. Disruption of the myelin sheath is observed in several neurological diseases, such as multiple sclerosis. A crucial component of myel
Externí odkaz:
https://doaj.org/article/622ddf4efa064a70bc8d47a1a10e6767
Autor:
Hark Kyun Kim, Junhyung Cho, Eunae Kim, Junsik Kim, Jeong‐Sun Yang, Kyung‐Chang Kim, Joo‐Yeon Lee, Younmin Shin, Leon F. Palomera, Jinsu Park, Seung Hyun Baek, Han‐Gyu Bae, Yoonsuk Cho, Jihoon Han, Jae Hoon Sul, Jeongmi Lee, Jae Hyung Park, Yong Woo Cho, Wonsik Lee, Dong‐Gyu Jo
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) entry is mediated by the interaction of the viral spike (S) protein with angiotensin‐converting enzyme 2 (ACE2) on the host cell surface. Although a clinical trial testing so
Externí odkaz:
https://doaj.org/article/b2d90fe84785407db997328c92421876
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Separated river systems could create confluences via two geological processes, estuary coalescence in response to decreasing sea levels and headwater capture, allowing primary freshwater species to disperse across rivers. Squalidus multimacu
Externí odkaz:
https://doaj.org/article/1c2bfbaa1a7e437aa77816288390c03b
Autor:
Li Yang Tan, Xin Yi Yeo, Han-Gyu Bae, Delia Pei Shan Lee, Roger C. Ho, Jung Eun Kim, Dong-Gyu Jo, Sangyong Jung
Publikováno v:
Life, Vol 11, Iss 7, p 698 (2021)
The central nervous system was classically perceived as anatomically and functionally independent from the other visceral organs. But in recent decades, compelling evidence has led the scientific community to place a greater emphasis on the role of g
Externí odkaz:
https://doaj.org/article/acc14e35ad9644abbd008f54f4dbe2e4
Autor:
Han-Gyu Bae, Yoon Jeong Lee, Hyung-Bae Jeon, Dong-Young Kim, Hari Won, Seulki Park, Junghwa An, Ho Young Suk
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 2, Iss 2, Pp 500-501 (2017)
The short ninespine stickleback, Pungitius kaibarae, is a small gasterosteid species complex containing three geographical lineages: ND, NE and SE. Here, complete mitochondrial genomes of these three lineages were analyzed to estimate the genetic dif
Externí odkaz:
https://doaj.org/article/6de400848c68492fabd5f20de7f97ecb
Autor:
Francesca Mandino, Ling Yun Yeow, Renzhe Bi, Lee Sejin, Han Gyu Bae, Seung Hyun Baek, Chun-Yao Lee, Hasan Mohammad, Corey Horien, Chai Lean Teoh, Jasinda H Lee, Mitchell KP Lai, Sangyong Jung, Yu Fu, Malini Olivo, John Gigg, Joanes Grandjean
Publikováno v:
Journal of Cerebral Blood Flow and Metabolism, 42, 1616-1631
Mandino, F, Yeow, L Y, Bi, R, Sejin, L, Bae, H G, Baek, S H, Lee, C-Y, Mohammad, H, Horien, C, Teoh, C L, Lee, J H, Lai, M K, Jung, S, Fu, Y, Olivo, M, Gigg, J & Grandjean, J 2022, ' The lateral entorhinal cortex is a hub for local and global dysfunction in early Alzheimer's disease states ', Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism . https://doi.org/10.1177/0271678x221082016
Journal of Cerebral Blood Flow and Metabolism, 42, 9, pp. 1616-1631
Mandino, F, Yeow, L Y, Bi, R, Sejin, L, Bae, H G, Baek, S H, Lee, C-Y, Mohammad, H, Horien, C, Teoh, C L, Lee, J H, Lai, M K, Jung, S, Fu, Y, Olivo, M, Gigg, J & Grandjean, J 2022, ' The lateral entorhinal cortex is a hub for local and global dysfunction in early Alzheimer's disease states ', Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism . https://doi.org/10.1177/0271678x221082016
Journal of Cerebral Blood Flow and Metabolism, 42, 9, pp. 1616-1631
Contains fulltext : 283318.pdf (Publisher’s version ) (Open Access) Functional network activity alterations are one of the earliest hallmarks of Alzheimer's disease (AD), detected prior to amyloidosis and tauopathy. Better understanding the neurona
Autor:
Tingxin Zhang, Han-Gyu Bae, Aksheev Bhambri, Yihe Zhang, Daniela Barbosa, Jumin Xue, Sabeen Wazir, Sara B. Mulinyawe, Jun Hee Kim, Lu O. Sun
Publikováno v:
bioRxiv
SUMMARYOligodendrocytes are the sole myelin producing cells in the central nervous system. Oligodendrocyte numbers are tightly controlled across diverse brain regions to match local axon type and number, but the underlying mechanisms and functional s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2da0d1188b1b8e5b49072bb310fdbc4
https://europepmc.org/articles/PMC9881874/
https://europepmc.org/articles/PMC9881874/