Výsledky vyhledávání - "Han Yeul Byun"

Efficacy of A/H1N1/2009 split inactivated influenza A vaccine (GC1115) in mice and ferrets

Autor: Su-Jin Park, Young Ki Choi, Suk-Hoon Ha, Norbert John Robles, Min-Suk Song, Hae Jung Han, Han Yeul Byun

Publikováno v: Journal of microbiology (Seoul, Korea). 57(2)

To evaluate the efficacy of a non-adjuvant A/H1N1/2009 influenza A vaccine (GC1115), we demonstrated the immunogenicity and protective efficacy of GC1115 in mouse and ferret models. The immunogenicity of GC1115 was confirmed after intramuscular admin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0559f0cb266d03d6a21ccb2e45e3afb8
https://pubmed.ncbi.nlm.nih.gov/30706345

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Use of a Target-Mediated Drug Disposition Model to Predict the Human Pharmacokinetics and Target Occupancy of GC1118, an Anti-epidermal Growth Factor Receptor Antibody

Autor: Taegon Hong, Seunghoon Han, Wan-Su Park, Dong-Seok Yim, Jongtae Lee, Yangmi Lim, Kyuhyun Lee, Han Yeul Byun, Jonghwa Won

Publikováno v: Basicclinical pharmacologytoxicology. 120(3)

GC1118 is an anti-epidermal growth factor receptor (EGFR) monoclonal antibody that is currently under clinical development. In this study, the pharmacokinetics (PK) of GC1118 were modelled in monkeys to predict human PK and receptor occupancy (RO) pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d58356851a0651b618d5a83ffd6066
https://pubmed.ncbi.nlm.nih.gov/27637171

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