Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Han Siean Lee"'
Autor:
Han Siean Lee, Michael Postan, Angela Song, Richard J. Clark, Ross A. D. Bathgate, Linda M. Haugaard-Kedström, K. Johan Rosengren
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Relaxin-3 is a neuropeptide with important roles in metabolism, arousal, learning and memory. Its cognate receptor is the relaxin family peptide-3 (RXFP3) receptor. Relaxin-3 agonist and antagonist analogs have been shown to be able to modulate food
Externí odkaz:
https://doaj.org/article/c183aee3f6d549afbc6228b8eaf12157
Autor:
Han Siean Lee, Shu Hui Wang, James T. Daniel, Mohammed Akhter Hossain, Richard J. Clark, Ross A. D. Bathgate, K. Johan Rosengren
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 415 (2020)
Relaxin-3 is a highly conserved two-chain neuropeptide that acts through its endogenous receptor the Relaxin Family Peptide-3 (RXFP3) receptor. The ligand/receptor system is known to modulate several physiological processes, with changes in food inta
Externí odkaz:
https://doaj.org/article/4dadaf45a31d4c4fabf6e020326105df
Autor:
Thao N. T. Ho, Lewis Goodwin, K. Johan Rosengren, Anne C. Conibear, Brianna Ushay, Han Siean Lee, Shilpa Swaminathan, Richard J. Lewis, Nishant Rai
Publikováno v:
RSC Med Chem
Conotoxins are peptides found in the venoms of marine cone snails. They are typically highly structured and stable and have potent activities at nicotinic acetylcholine receptors, which make them valuable research tools and promising lead molecules f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b726e9c57859fadb8d2e4d02bfca4778
https://doi.org/10.1039/d1md00182e
https://doi.org/10.1039/d1md00182e
Autor:
Jenny N. Fung, Han Siean Lee, Barbara E. Rolfe, Xaria X. Li, Declan M. Gorman, John D. Lee, Trent M. Woodruff, Richard J. Clark, Cedric S. Cui
Publikováno v:
Journal of medicinal chemistry. 64(22)
The anaphylatoxin C5a is a complement peptide associated with immune-related disorders. C5a binds with equal potency to two GPCRs, C5aR1 and C5aR2. Multiple C5a peptide agonists have been developed to interrogate the C5a receptor function but none sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1799b782d3de026c8be866a53908ae4e
https://pubmed.ncbi.nlm.nih.gov/34762432
https://pubmed.ncbi.nlm.nih.gov/34762432
Autor:
James T. Daniel, K. Johan Rosengren, Shu Hui Wang, Richard J. Clark, Ross A. D. Bathgate, Mohammed Akhter Hossain, Han Siean Lee
Publikováno v:
Biomedicines, Vol 8, Iss 415, p 415 (2020)
Biomedicines
Volume 8
Issue 10
Biomedicines
Volume 8
Issue 10
Relaxin-3 is a highly conserved two-chain neuropeptide that acts through its endogenous receptor the Relaxin Family Peptide-3 (RXFP3) receptor. The ligand/receptor system is known to modulate several physiological processes, with changes in food inta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2583b523742ccae3bdd75509f9299e0a
https://www.mdpi.com/2227-9059/8/10/415
https://www.mdpi.com/2227-9059/8/10/415
Autor:
Han Siean Lee
Relaxin-3, a member of the insulin/relaxin superfamily, has been shown to be involved in modulating several neurophysiological process including food intake, stress, addiction, arousal, memory and learning in animal models. Its sequence is highly evo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e99404da4ce1694aef0e5ac4fc5972
https://doi.org/10.14264/uql.2020.829
https://doi.org/10.14264/uql.2020.829
Autor:
Han Siean Lee, Linda M. Haugaard-Kedström, Angela Song, Ross A. D. Bathgate, Michael Postan, K. Johan Rosengren, Richard J. Clark
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 8 (2020)
Frontiers in Chemistry, Vol 8 (2020)
Relaxin-3 is a neuropeptide with important roles in metabolism, arousal, learning and memory. Its cognate receptor is the relaxin family peptide-3 (RXFP3) receptor. Relaxin-3 agonist and antagonist analogs have been shown to be able to modulate food
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362932708eb945d15d0cf5799d6803c3
https://pubmed.ncbi.nlm.nih.gov/32133341
https://pubmed.ncbi.nlm.nih.gov/32133341
Autor:
Gorman, Declan M., Li, Xaria X., Lee, John D., Fung, Jenny N., Cui, Cedric S., Han Siean Lee, Rolfe, Barbara E., Woodruff, Trent M., Clark, Richard J.
Publikováno v:
Journal of Medicinal Chemistry; 11/25/2021, Vol. 64 Issue 22, p16598-16608, 11p
Autor:
Annemie Deiteren, Bodil B. Carstens, Richard J. Clark, Mahsa Sadeghi, David J. Adams, Stuart M. Brierley, Kathryn A. V. Jackson, Han Siean Lee, James T. Daniel, Géza Berecki, Han-Shen Tae, Tracy O'Donnell, Joel Castro, David J. Craik
Publikováno v:
Angewandte Chemie International Edition. 55:4692-4696
α-Conotoxins are disulfide-rich peptides that target nicotinic acetylcholine receptors. Recently we identified several α-conotoxins that also modulate voltage-gated calcium channels by acting as G protein-coupled GABA(B) receptor (GABA(B)R) agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9905913f5dd49b201e7fe2f1b7678e
https://doi.org/10.1002/anie.201600297
https://doi.org/10.1002/anie.201600297
Autor:
Bodil B. Carstens, Géza Berecki, James T. Daniel, Han Siean Lee, Kathryn A. V. Jackson, Han‐Shen Tae, Mahsa Sadeghi, Joel Castro, Tracy O'Donnell, Annemie Deiteren, Stuart M. Brierley, David J. Craik, David J. Adams, Richard J. Clark
Publikováno v:
Angewandte Chemie. 128:4770-4774
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67491accc7a3ab02ecf7967ade1593d2
https://doi.org/10.1002/ange.201600297
https://doi.org/10.1002/ange.201600297