Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Han She"'
Autor:
Han She, Lei Tan, Yi Wang, Yuanlin Du, Yuanqun Zhou, Jun Zhang, Yunxia Du, Ningke Guo, Zhengbin Wu, Qinghui Li, Daiqin Bao, Qingxiang Mao, Yi Hu, Liangming Liu, Tao Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/da10ce1c7e744415ac432bd7a8d2316b
Autor:
Han She, Yuanlin Du, Yunxia Du, Lei Tan, Shunxin Yang, Xi Luo, Qinghui Li, Xinming Xiang, Haibin Lu, Yi Hu, Liangming Liu, Tao Li
Publikováno v:
BMC Anesthesiology, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Sepsis is a life-threatening disease with a poor prognosis, and metabolic disorders play a crucial role in its development. This study aims to identify key metabolites that may be associated with the accurate diagnosis and prognos
Externí odkaz:
https://doaj.org/article/fe7e8f14d06a4a79a93629732a3d26ab
Autor:
Lei Tan, Han She, Jie Zheng, Xiaoyong Peng, Ningke Guo, Bindan Zhang, Yue Sun, Chunhua Ma, Shenglian Xu, Daiqin Bao, Yuanqun Zhou, Qinghui Li, Qingxiang Mao, Liangming Liu, Yi Hu, Tao Li
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Background Myocardial dysfunction played a vital role in organ damage after sepsis. Fluid resuscitation was the essential treatment in which Lactate Ringer's solution (LR) was commonly used. Since LR easily led to hyperlactatemia, its resusc
Externí odkaz:
https://doaj.org/article/9625d603dd0b492b8d2517cd67fd3911
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundSepsis remains a complex condition with incomplete understanding of its pathogenesis. Further research is needed to identify prognostic factors, risk stratification tools, and effective diagnostic and therapeutic targets.MethodsThree GEO da
Externí odkaz:
https://doaj.org/article/6d861644b896449486d4f9e97b5ac94e
Autor:
Han She, Lei Tan, Yi Wang, Yuanlin Du, Yuanqun Zhou, Jun Zhang, Yunxia Du, Ningke Guo, Zhengbin Wu, Qinghui Li, Daiqin Bao, Qingxiang Mao, Yi Hu, Liangming Liu, Tao Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTo identify differentially expressed lipid metabolism-related genes (DE-LMRGs) responsible for immune dysfunction in sepsis.MethodsThe lipid metabolism-related hub genes were screened using machine learning algorithms, and the immune cell i
Externí odkaz:
https://doaj.org/article/0906682e28f64d92862874c532fcdf61
Autor:
Han She, Lei Tan, Ruibo Yang, Jie Zheng, Yi Wang, Yuanlin Du, Xiaoyong Peng, Qinghui Li, Haibin Lu, Xinming Xiang, Yi Hu, Liangming Liu, Tao Li
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: The precise diagnostic and prognostic biological markers were needed in immunotherapy for sepsis. Considering the role of necroptosis and immune cell infiltration in sepsis, differentially expressed necroptosis-related genes (DE-NRGs) wer
Externí odkaz:
https://doaj.org/article/07fcde89b2034c79803ceb5a7d0792ae
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Previous studies found that seawater immersion combined with hemorrhagic shock (SIHS) induced serious organ function disorder, and lethal triad was a critical sign. There were no effective treatments of SIHS. Fluid resuscitation was the initial measu
Externí odkaz:
https://doaj.org/article/8d470a2c393d4469b41d5f3dcef92f45
Autor:
Han She, Lei Tan, Yuanqun Zhou, Yu Zhu, Chunhua Ma, Yue Wu, Yuanlin Du, Liangming Liu, Yi Hu, Qingxiang Mao, Tao Li
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Sepsis is a heterogeneous disease state triggered by an uncontrolled inflammatory host response with high mortality and morbidity in severely ill patients. Unfortunately, the treatment effectiveness varies among sepsis patients and the underlying mec
Externí odkaz:
https://doaj.org/article/8d1a9f5c9cfe49c8be87ae3c81962113
Autor:
Yu Zhu, Lei Kuang, Yue Wu, Haoyue Deng, Han She, Yuanqun Zhou, Jie Zhang, Liangming Liu, Tao Li
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Sepsis-associated organ dysfunction plays a critical role in its high mortality, mainly in connection with mitochondrial dysfunction. Whether the inhibition of mitochondrial fission is beneficial to sepsis-related organ dysfunction and underlying mec
Externí odkaz:
https://doaj.org/article/d07b61b102f44976bfc03d5ac3f13159
Autor:
Han She, Yu Zhu, Haoyue Deng, Lei Kuang, He Fang, Zisen Zhang, Chenyang Duan, Jiaqing Ye, Jie Zhang, Liangming Liu, Yi Hu, Tao Li
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The damage of vascular endothelial barrier function induced by sepsis is critical in causing multiple organ dysfunctions. Previous studies showed that dexmedetomidine (Dex) played a vital role in protecting organ functions. However, whether Dex parti
Externí odkaz:
https://doaj.org/article/ed033b26efc14b368c2ea5066c4aaec1