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Akademický článek

The effect of diabetes and prediabetes on the prevalence, complications and mortality in nonalcoholic fatty liver disease

Autor: Cheng Han Ng, Kai En Chan, Yip Han Chin, Rebecca Wenling Zeng, Pei Chen Tsai, Wen Hui Lim, Darren Jun Hao Tan, Chin Meng Khoo, Lay Hoon Goh, Zheng Jye Ling, Anand Kulkarni, Lung-Yi Loey Mak, Daniel Q Huang, Mark Chan, Nicholas WS Chew, Mohammad Shadab Siddiqui, Arun J. Sanyal, Mark Muthiah

Publikováno v: Clinical and Molecular Hepatology, Vol 28, Iss 3, Pp 565-574 (2022)

Background/Aims Nonalcoholic fatty liver disease (NAFLD) is closely associated with diabetes. The cumulative impact of both diseases synergistically increases risk of adverse events. However, present population analysis is predominantly conducted wit

Externí odkaz: https://doaj.org/article/737e07a73dbf4a638075e146e094357a

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Akademický článek

Non-alcoholic fatty liver disease increases risk of carotid atherosclerosis and ischemic stroke: An updated meta-analysis with 135,602 individuals

Publikováno v: Clinical and Molecular Hepatology, Vol 28, Iss 3, Pp 483-496 (2022)

Background/Aims Non-alcoholic fatty liver disease (NAFLD) is associated with the development of cardiovascular disease. While existing studies have examined cardiac remodeling in NAFLD, there has been less emphasis on the development of carotid ather

Externí odkaz: https://doaj.org/article/6b6d5630aac840db9fc0557d9bb72d6f

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Akademický článek

Can glucose‐lowering medications improve outcomes in non‐diabetic heart failure patients? A Bayesian network meta‐analysis

Autor: Trevor Yeong, Aaron Shengting Mai, Oliver Z.H. Lim, Cheng Han Ng, Yip Han Chin, Phoebe Tay, Chaoxing Lin, Mark Muthiah, Chin Meng Khoo, Mayank Dalakoti, Poay‐Huan Loh, Mark Chan, Tiong‐Cheng Yeo, Roger Foo, Raymond Wong, Nicholas W.S. Chew, Weiqin Lin

Publikováno v: ESC Heart Failure, Vol 9, Iss 2, Pp 1338-1350 (2022)

Abstract Aims The cardioprotective effects of glucose‐lowering medications in diabetic patients with heart failure (HF) are well known. Several large randomized controlled trials (RCTs) have recently suggested that the cardioprotective effects of g

Externí odkaz: https://doaj.org/article/9fb3550ca5c449988fd18018af712751

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Akademický článek

Global Prevalence, Risk Factors, and Outcomes of Depression After Liver Transplant: A Systematic Review and Meta-analysis

Autor: Wen Hui Lim, Chen Wei Poh, Beatrice Jia Min Tan, Cheng Han Ng, Darren Jun Hao Tan, Xiong Chang Lim, Phoebe Wen Lin Tay, Grace En Hui Lim, Daniel Q. Huang, Cyrus S.H. Ho, Eunice Xiang-Xuan Tan, Nicholas Syn, Yock Young Dan, Konstadina Griva, James Fung, Mohammad Shadab Siddiqui, Mark Dhinesh Muthiah

Publikováno v: Gastro Hep Advances, Vol 1, Iss 2, Pp 150-159 (2022)

Background and aims: With existing literature focusing on general quality of life, the magnitude and impact of depression among recipients after liver transplantation (LT) is unclear. Hence, we aim to evaluate the prevalence, risk factors, and outcom

Externí odkaz: https://doaj.org/article/450cf72a2ada4d0aace146eb1a1baa40

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Akademický článek

The placebo response rate and nocebo events in obesity pharmacological trials. A systematic review and meta-analysis

Publikováno v: EClinicalMedicine, Vol 54, Iss , Pp 101685- (2022)

Summary: Background: There is a growing number of trials examining the effectiveness of pharmacotherapies for obesity, however, little is known about placebo and nocebo effect in these trials. Hence, we sought to examine the effect of placebo in obes

Externí odkaz: https://doaj.org/article/222cbfecf9a94fc1ac2610b7ce7335d8

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Akademický článek

Depression in non-alcoholic fatty liver disease is associated with an increased risk of complications and mortality

Publikováno v: Frontiers in Medicine, Vol 9 (2022)

Background and aimsThe global prevalence of non-alcoholic fatty liver disease (NAFLD) is expected to rise continuously. Furthermore, emerging evidence has also shown the potential for concomitant depression in NAFLD. This study aims to examine the pr

Externí odkaz: https://doaj.org/article/8eea24be9617447baaec8753cb81ac46

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Akademický článek

The genetic interactions between non-alcoholic fatty liver disease and cardiovascular diseases

Autor: Nicholas W.S. Chew, Bryan Chong, Cheng Han Ng, Gwyneth Kong, Yip Han Chin, Wang Xiao, Mick Lee, Yock Young Dan, Mark D. Muthiah, Roger Foo

Publikováno v: Frontiers in Genetics, Vol 13 (2022)

The ongoing debate on whether non-alcoholic fatty liver disease (NAFLD) is an active contributor or an innocent bystander in the development of cardiovascular disease (CVD) has sparked interests in understanding the common mediators between the two b

Externí odkaz: https://doaj.org/article/65605b0fb2614d2a9a235f7a16b53531

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