Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Han N. Lim"'
Publikováno v:
Biology Open, Vol 5, Iss 12, Pp 1882-1893 (2016)
Quantifying the localization of molecules with respect to other molecules, cell structures and intracellular regions is essential to understanding their regulation and actions. However, measuring localization from microscopy images is often difficult
Externí odkaz:
https://doaj.org/article/571d151c44be40dd950043ae227cd6a4
Autor:
David N Adamson, Han N Lim
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 8, p e1002138 (2011)
Bacteria possess networks of small RNAs (sRNAs) that are important for modulating gene expression. At the center of many of these sRNA networks is the Hfq protein. Hfq's role is to quickly match cognate sRNAs and target mRNAs from among a large numbe
Externí odkaz:
https://doaj.org/article/15d842c8915f4280b540f0cdd965f5b2
Publikováno v:
Nucleic Acids Research
Shin, Jung-Eun; Lin, Chris; & Lim, Han N. (2016). Horizontal transfer of DNA methylation patterns into bacterial chromosomes. Nucleic Acids Research, 44(9), 4460-4471. doi: 10.1093/nar/gkw230. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/9gb8f5k1
Shin, Jung-Eun; Lin, Chris; & Lim, Han N. (2016). Horizontal transfer of DNA methylation patterns into bacterial chromosomes. Nucleic Acids Research, 44(9), 4460-4471. doi: 10.1093/nar/gkw230. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/9gb8f5k1
Horizontal gene transfer (HGT) is the non-inherited acquisition of novel DNA sequences. HGT is common and important in bacteria because it enables the rapid generation of new phenotypes such as antibiotic resistance. Here we show that in vivo and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb27ce40e5957d1802ae40de4f825a45
http://europepmc.org/articles/PMC4872104
http://europepmc.org/articles/PMC4872104
Publikováno v:
Stauffer, Weston; Sheng, Huanjie; & Lim, Han N. (2018). EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms. Scientific Reports, 8(1). doi: 10.1038/s41598-018-33592-8. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/3w53j7z0
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Insight into the function and regulation of biological molecules can often be obtained by determining which cell structures and other molecules they localize with (i.e. colocalization). Here we describe an open source plugin for ImageJ called EzColoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff69c82b81623bc5b6d2ce7c7223329
https://doi.org/10.1038/s41598-018-33592-8
https://doi.org/10.1038/s41598-018-33592-8
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1849:940-954
Rho factor dependent transcription termination (RTT) is common within the coding sequences of bacterial genes and it acts to couple transcription and translation levels. Despite the importance of RTT for gene regulation, its effects on mRNA and prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c58b28a8d2652fbfff277780755279
https://doi.org/10.1016/j.bbagrm.2015.05.003
https://doi.org/10.1016/j.bbagrm.2015.05.003
Publikováno v:
Biology Open
Biology Open, Vol 5, Iss 12, Pp 1882-1893 (2016)
Biology Open, Vol 5, Iss 12, Pp 1882-1893 (2016)
Quantifying the localization of molecules with respect to other molecules, cell structures and intracellular regions is essential to understanding their regulation and actions. However, measuring localization from microscopy images is often difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058e022b2efca66c4c642dc612415d1e
https://pubmed.ncbi.nlm.nih.gov/27979831
https://pubmed.ncbi.nlm.nih.gov/27979831
Autor:
David N. Adamson, Han N. Lim
Publikováno v:
Proceedings of the National Academy of Sciences. 110:13120-13125
Bacterial survival requires the rapid propagation of signals through gene networks during stress, but how this is achieved is not well understood. This study systematically characterizes the signaling dynamics of a cascade of RNA–protein interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc026a72fe101f89847496a296c147bb
https://doi.org/10.1073/pnas.1308476110
https://doi.org/10.1073/pnas.1308476110
Publikováno v:
Nucleic Acids Research
Bacterial small RNAs (sRNAs) regulate protein production by binding to mRNAs and altering their translation and degradation. sRNAs are smaller than most mRNAs but larger than many proteins. Therefore it is uncertain whether sRNAs can enter the nucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0a4eeff85e0545f30b588291f1b361
https://pubmed.ncbi.nlm.nih.gov/28119418
https://pubmed.ncbi.nlm.nih.gov/28119418
Publikováno v:
Nucleic Acids Research
Gene translocations play an important role in the plasticity and evolution of bacterial genomes. In this study, we investigated the impact on gene regulation of three genome organizational features that can be altered by translocations: (i) chromosom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c646b50c7052f2b06b4853b17d49ac
https://doi.org/10.1093/nar/gks694
https://doi.org/10.1093/nar/gks694
Autor:
Razika Hussein, Han N. Lim
Publikováno v:
Nucleic Acids Research
Small RNAs (sRNAs) and proteins acting as transcription factors (TFs) are the principal components of gene networks. These two classes of signaling molecules have distinct mechanisms of action; sRNAs control mRNA translation, whereas TFs control mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df35f09c6df12c0be7435a17219a44f
https://doi.org/10.1093/nar/gks439
https://doi.org/10.1093/nar/gks439