Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Han Moshage"'
Autor:
Magnolia Martínez-Aguilar, María Camila Trillos-Almanza, Justina C. Wolters, Manon Buist-Homan, TransplantLines Investigators, Frederike van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 2, Pp 143-162 (2024)
Aim: Extracellular vesicles (EVs) have gained significant attention for their diagnostic and therapeutic potential in various diseases, including liver disorders. This study focuses on optimizing the isolation and characterization of small EVs from p
Externí odkaz:
https://doaj.org/article/fac795c2bb8b4781962d863728fd9087
Autor:
Maria Camila Trillos-Almanza, Magnolia Martinez-Aguilar, Johanna C. Arroyave-Ospina, Frederike van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Muscles, Vol 3, Iss 1, Pp 71-87 (2024)
This comprehensive review focuses on the dynamics of branched-chain amino acids (BCAAs) metabolism and its clinical implications in chronic liver disease, with emphasis on the emerging concept of muscle–liver crosstalk. BCAAs, indispensable for pro
Externí odkaz:
https://doaj.org/article/da692d15f16d4affae7549d8014fc3cb
Autor:
Maria Camila Trillos-Almanza, Mateo Chvatal-Medina, Margery A. Connelly, Han Moshage, TransplantLines Investigators, Stephan J. L. Bakker, Vincent E. de Meijer, Hans Blokzijl, Robin P. F. Dullaart
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6031 (2024)
Liver transplant recipients (LTRs) have lower long-term survival rates compared with the general population. This underscores the necessity for developing biomarkers to assess post-transplantation mortality. Here we compared plasma trimethylamine-N-o
Externí odkaz:
https://doaj.org/article/f7ed13eb67a7426ca1b6846ce5b0ab99
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 114884- (2023)
Background: Epidemiological evidence has shown an association between coffee consumption and reduced risk for chronic liver diseases, including metabolic-dysfunction-associated liver disease (MALFD). Lipotoxicity is a key cause of hepatocyte injury d
Externí odkaz:
https://doaj.org/article/ca4516ada5f14526b4ac0ff150eac41e
Autor:
Zongmei Wu, Mengmeng Xia, Sandra Serna Salas, Maria Camila Trillos-Almanza, Magnolia Martinez Aguilar, Johanna C. Arroyave-Ospina, Junyu Wang, Marco Arrese, Svenja Sydor, Lars P. Bechmann, Frederike GI van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Exploration of Digestive Diseases, Vol 1, Iss 1, Pp 4-20 (2022)
The prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) is increasing rapidly worldwide due to the obesity epidemic. Advanced stages of the MAFLD, such as non-alcoholic steatohepatitis (NASH) with advanced fibrosis or cirrhosis
Externí odkaz:
https://doaj.org/article/ea74b7ba35244121ac69087233bb96a4
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1922 (2023)
Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-associated fatty liver disease (MAFLD). However, the mechanisms underlying their beneficial effects remain unclear. In the present study, we explored the potenti
Externí odkaz:
https://doaj.org/article/c1c5e77e792a40039ee733223c3ae9f1
Autor:
Maria Camila Trillos-Almanza, Hanna Wessel, Magnolia Martínez-Aguilar, Eline H. van den Berg, Rianne M. Douwes, Han Moshage, Margery A. Connelly, Stephan J. L. Bakker, Vincent E. de Meijer, Robin P. F. Dullaart, Hans Blokzijl
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 824 (2023)
Decreased circulating branched chain amino acids (BCAA) represent a prominent change in amino acid profiles in patients with end-stage liver disease (ESLD). These alterations are considered to contribute to sarcopenia and hepatic encephalopathy and m
Externí odkaz:
https://doaj.org/article/52adda2308304a418651fd6ac5bacbda
Autor:
Gloria Stephanie Villa-Jaimes, Fabio Alejandro Aguilar-Mora, Herson Antonio González-Ponce, Francisco Javier Avelar-González, Ma. Consolación Martínez Saldaña, Manon Buist-Homan, Han Moshage
Publikováno v:
Journal of Functional Foods, Vol 89, Iss , Pp 104960- (2022)
This study aimed to investigate whether Opuntia spp-extracts protect against diclofenac (DF)-induced hepatotoxicity. Rats were pretreated with Opuntia extracts, betanin (Bet) and N-acetylcysteine (NAC) followed by a single challenge of diclofenac. Li
Externí odkaz:
https://doaj.org/article/de307c2eef314934baec1ed128c31a56
Autor:
Gloria Stephanie Villa-Jaimes, Han Moshage, Francisco Javier Avelar-González, Herson Antonio González-Ponce, Manon Buist-Homan, Fidel Guevara-Lara, Esperanza Sánchez-Alemán, Sandra Luz Martínez-Hernández, Javier Ventura-Juárez, Martín Humberto Muñoz-Ortega, Ma. Consolación Martínez-Saldaña
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 113 (2023)
A molecular characterization of the main phytochemicals and antioxidant activity of Opuntia robusta (OR) fruit extract was carried out, as well as an evaluation of its hepatoprotective effect against diclofenac (DF)-induced acute liver injury was eva
Externí odkaz:
https://doaj.org/article/7165c3f6cfa24eed8de24ad1ad6073ef
Autor:
Fabio Alejandro Aguilar Mora, Nshunge Musheshe, Johanna C. Arroyave Ospina, Yana Geng, Juan M. Soto, José A. Rodrigo, Tatiana Alieva, Manon Buist-Homan, Frank Lezoualc'h, Xiaodong Cheng, Martina Schmidt, Han Moshage
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 143, Iss , Pp 112072- (2021)
Background and purpose: It has been shown that the antidiabetic drug metformin protects hepatocytes against toxicity by various stressors. Chronic or excessive consumption of diclofenac (DF) - a pain-relieving drug, leads to drug-induced liver injury
Externí odkaz:
https://doaj.org/article/9b6fa0040eae43c6bbcfedc1ef4e0d82