Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Han Li Huang"'
Autor:
Ting-Yi Sung, Han-Li Huang, Chun-Chun Cheng, Fu-Ling Chang, Po-Li Wei, Ya-Wen Cheng, Cheng-Chiao Huang, Yu-Ching Lee, Wei-Chun HuangFu, Shiow-Lin Pan
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Background The availability of a reliable tumor target for advanced colorectal cancer (CRC) therapeutic approaches is critical since current treatments are limited. Epidermal growth factor-like domain 6 (EGFL6) has been reported to be associ
Externí odkaz:
https://doaj.org/article/9bbf162c729e43c9b4a3fe7a24f4256f
Publikováno v:
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Despite the fact that histone deacetylase (HDAC) inhibitors have been tested to treat various cardiovascular diseases, the effects of selective HDAC6 inhibitor ACY1215 on infarct size during cardiac ischemia-reperfusion (IR) injur
Externí odkaz:
https://doaj.org/article/4f10a02731db406088ea9d201791927e
Publikováno v:
Sustainability; Volume 15; Issue 12; Pages: 9301
In implementing an innovation-driven development strategy, it is important to promote the sustainable development capacity of the new generation. Entrepreneurial learning can enhance college students’ skills and entrepreneurial competence in facing
Autor:
Tony Eight Lin, Wei-Chun HuangFu, Min-Wu Chao, Tzu-Ying Sung, Chao-Di Chang, Yi-Ying Chen, Jui-Hua Hsieh, Huang-Ju Tu, Han-Li Huang, Shiow-Lin Pan, Kai-Cheng Hsu
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The JAK2/STAT signaling pathway mediates cytokine receptor signals that are involved in cell growth, survival and homeostasis. JAK2 is a member of the Janus kinase (JAK) family and aberrant JAK2/STAT is involved with various diseases, making the path
Externí odkaz:
https://doaj.org/article/53feeaf4e47a4482ada47bbc6e155336
Autor:
En-Chi Hsu, Samuel K. Kulp, Han-Li Huang, Huang-Ju Tu, Santosh B. Salunke, Nicholas J. Sullivan, Duxin Sun, Max S. Wicha, Charles L. Shapiro, Ching-Shih Chen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 6, Pp 497-508 (2015)
Interleukin-6 (IL-6) and Notch signaling are important regulators of breast cancer stem cells (CSCs), which drive the malignant phenotype through self-renewal, differentiation, and development of therapeutic resistance. We investigated the role of in
Externí odkaz:
https://doaj.org/article/12a299e1a5344f7dbab1382a814fe3d7
Autor:
Mei-Jung Lai, Hsueh-Yun Lee, Hsun-Yueh Chuang, Li-Hsun Chang, An-Chi Tsai, Mei-Chuan Chen, Han-Li Huang, Yi-Wen Wu, Che-Ming Teng, Shiow-Lin Pan, Yi-Min Liu, Samir Mehndiratta, Jing-Ping Liou
Publikováno v:
Journal of Medicinal Chemistry. 66:6436-6436
Autor:
Tzu Ying Sung, Liang Chieh Chen, Ssu Ting Lien, Yi Wen Wu, Sin Ting Ngo, Shiow Lin Pan, Shih Chung Yen, Hui Ju Tseng, Kai Cheng Hsu, Tony Eight Lin, Han Li Huang, Wei Jan Huang
Publikováno v:
Journal of Natural Products. 84:1-10
Acute myeloid leukemia (AML) is an aggressive disease with a poor prognosis and a high degree of relapse seen in patients. Overexpression of FMS-like tyrosine kinase 3 (FLT3) is associated with up to 70% of AML patients. Wild-type FLT3 induces prolif
Publikováno v:
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-8 (2020)
BMC Pharmacology & Toxicology
BMC Pharmacology & Toxicology
Background Despite the fact that histone deacetylase (HDAC) inhibitors have been tested to treat various cardiovascular diseases, the effects of selective HDAC6 inhibitor ACY1215 on infarct size during cardiac ischemia-reperfusion (IR) injury still r
Autor:
Shih-Chung Yen, Liang-Chieh Chen, Han-Li Huang, Wei-Chun HuangFu, Yi-Ying Chen, Tony Eight Lin, Ssu-Ting Lien, Hui-Ju Tseng, Tzu-Ying Sung, Jui-Hua Hsieh, Wei-Jan Huang, Shiow-Lin Pan, Kai-Cheng Hsu
Publikováno v:
Bioorganic chemistry. 121
Fms-like tyrosine kinase 3 (FLT3) is considered a promising therapeutic target for acute myeloid leukemia (AML) in the clinical. However, monotherapy with FLT3 inhibitor is usually accompanied by drug resistance. Dual inhibitors might be therapeutica
Autor:
Shiow Lin Pan, Tsui Chin Huang, Ya Wen Cheng, Han Li Huang, Yi Min Liu, Ting Yi Sung, Jing Ping Liou
Publikováno v:
Theranostics
Tissue inhibitors of metalloproteinase 3 (TIMP3) are a major endogenous inhibitor of matrix metalloproteinase (MMPs) that inhibit tumor growth, invasion, metastasis and angiogenesis. In this study, we found that TIMP3 expression is associated with po