Zobrazeno 1 - 10
of 874
pro vyhledávání: '"Han Dai"'
Autor:
Mengfang Yan, Zijie Su, Xiaoyi Pang, Hanbin Wang, Han Dai, Jiong Ning, Shanshan Liu, Qi Sun, Jiaxing Song, Xibao Zhao, Desheng Lu
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2277-2297 (2024)
Casein kinase 1ε (CK1ε) and axis inhibitor 1 (AXIN1) are crucial components of the β‐catenin destruction complex in canonical Wnt signaling. CK1ε has been shown to interact with AXIN1, but its physiological function and role in tumorigenesis re
Externí odkaz:
https://doaj.org/article/f7d4e374ffa04ddc88efd2b791dc294b
Autor:
Lele Ai, Yong Qi, Yue Hu, Changqiang Zhu, Kangle Liu, Feng Li, Fuqiang Ye, Han Dai, Yifan Wu, Qiyuan Kuai, Danyue Nie, Laiyou Shan, Yan Zhang, Changjun Wang, Weilong Tan
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Coxiella burnetii (C. burnetii) is the causative agent of Q fever, a type of zoonoses withwidespread distribution. In 2019, a case of Q fever was diagnosed by metagenomic next-generation sequencing (mNGS) method in Xuyi County (Jiangsu provi
Externí odkaz:
https://doaj.org/article/c472e29cc3bf42f6ad0e824636b4c905
Autor:
Xu Bi, Xiaotong Guo, Wencheng Song, Dandan Shi, Shuyue Tan, Youzheng Sun, Weiye Zhang, Hao Kang, Yanyan Li, Han Dai, Junfeng Zhao
Publikováno v:
Electrochemistry Communications, Vol 167, Iss , Pp 107796- (2024)
Because of the presence of electrochemically inactive C-F2 bond and poor electronic conductivity of C-F, the discharge performance of lithium fluorocarbon (Li/CFx) batteries is limited, despite their extensive use in commercial fields. In this study,
Externí odkaz:
https://doaj.org/article/3143e6b685724a77b060c845d00d00c8
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The phospholipid bilayer nanodiscs (LNDs), as a rapidly-developing tool in recent years, provide a natural bio-memebrane environment to maintain the native conformation and functions of membrane proteins as well as a versatile delivery vehicle for a
Externí odkaz:
https://doaj.org/article/4872d585bc7c493fa76b01361580a2e1
Autor:
Sapna Sayed, Mehdihasan Shekh, Jiaxing Song, Qi Sun, Han Dai, Vivian Weiwen Xue, Shanshan Liu, Bing Du, Guangqian Zhou, Florian J. Stadler, Guangming Zhu, Desheng Lu
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100849- (2023)
There is a high demand for an optimal drug delivery system to treat androgenetic alopecia. Topical application of ISX9, which is a neurogenesis inducer, has been found to stimulate hair follicle (HF) regrowth by upregulating the Wnt/β-catenin signal
Externí odkaz:
https://doaj.org/article/8860a9bfddc54b7da1afbd3af9d94c3b
Autor:
Hao Wang, Yanping Wang, Hongmin Zhang, Zerong Liang, Wenjing Hu, Sheng Qiu, Ke Li, Lili Zhang, Han Dai, Mengliu Yang, Gangyi Yang, Ling Li
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractBackground Although a study found a significant increase in serum hedgehog interacting protein (HHIP) concentrations in impaired fasting blood glucose, impaired glucose tolerance and newly diagnosed T2DM patients, the variation in circulating
Externí odkaz:
https://doaj.org/article/1e360206b5474bd2a3c2a95a777ff874
Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins
Autor:
Chuandi Yu, Wen Ding, Lei Zhu, Yuhang Zhou, Yingkui Dong, Ling Li, Juanjuan Liu, Yizhuo Wang, Zehua Li, Lina Zhu, FaJun Chen, Maosen Ruan, Dongming Qian, Yujuan Wang, Bo Wu, Huangtao Xu, Ming Li, Yunchen Bi, Hao Wang, Weiqian Wang, Peng Chao, Lei Xing, Bing Shen, Han Dai, Lisha Zha, Hongxin Zhao, Junfeng Wang
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105736- (2023)
Summary: Influenza A virus poses a constant challenge to human health. The highly conserved influenza matrix-2 (M2) protein is an attractive target for the development of a universal antibody-based drug. However, screening using antigens with subphys
Externí odkaz:
https://doaj.org/article/1a78a5e934174b078a443c01a3f376a5
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Congenital disorders of glycosylation (CDG) are a group of metabolic diseases with clinical and genetic heterogeneity, and CDG-IIg is one of the rare reported types of CDG. The aim of this study is to report the clinical manifesta
Externí odkaz:
https://doaj.org/article/000f87efca724596b782f256f4203765
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Targeting proteins’ enzymatic functions with small molecule inhibitors, as well as functions of receptor proteins with small-molecule agonists and antagonists, were the major forms of small-molecule drug development. These small-molecule modulators
Externí odkaz:
https://doaj.org/article/a22d25d35f4a48d6a3ea861bee5576bc
Publikováno v:
AIP Advances, Vol 12, Iss 7, Pp 075202-075202-10 (2022)
Solidification phases of conventional cast aerospace Al–Cu–Mg alloys and their evolution during homogenization were comprehensively studied. Significant refinement and spheroidization of solidification phases were found by the addition of 0.04, 0
Externí odkaz:
https://doaj.org/article/f10ead8bf01a444b8ae16c077b077f29