Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Han‐Yuan Liu"'
Autor:
Zhengnian Li, Han‐Yuan Liu, Zhixiang He, Antara Chakravarty, Ryan P. Golden, Zixuan Jiang, Inchul You, Hong Yue, Katherine A. Donovan, Guangyan Du, Jianwei Che, Jason Tse, Isaac Che, Wenchao Lu, Eric S. Fischer, Tinghu Zhang, Nathanael S. Gray, Priscilla L. Yang
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Targeted protein degradation has been widely adopted as a new approach to eliminate both established and previously recalcitrant therapeutic targets. Here, it is reported that the development of small molecule degraders of the envelope (E) p
Externí odkaz:
https://doaj.org/article/d886eb34b9c74a7eabd320cf5081d214
Autor:
Han-Yuan Liu, Zhengnian Li, Theresia Reindl, Zhixiang He, Xueer Qiu, Ryan P. Golden, Katherine A. Donovan, Adam Bailey, Eric S. Fischer, Tinghu Zhang, Nathanael S. Gray, Priscilla L. Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Viral genetic diversity presents significant challenges in developing antivirals with broad-spectrum activity and high barriers to resistance. Here we report development of proteolysis targeting chimeras (PROTACs) targeting the dengue virus
Externí odkaz:
https://doaj.org/article/7d9b7ee5a0a0432baec898202007a68e
Publikováno v:
Green Synthesis and Catalysis, Vol 4, Iss 1, Pp 64-66 (2023)
Allyl protection is widely used in organic synthesis. Herein, we describe an efficient and general protocol for O-deallylation via cobalt hydride-catalyzed oxidative hydrofunctionalization. Using a green oxidant, namely oxone, this method smoothly de
Externí odkaz:
https://doaj.org/article/ca6795e98bb74bf78294c4fe262b661a
Publikováno v:
Current Oncology, Vol 29, Iss 2, Pp 1201-1212 (2022)
Background: The effect of multidisciplinary team intervention (MDT) on the prognosis of advanced gastric cancer (GC) is still controversial. This study aims to analyze the effect of MDTs on the overall survival time of advanced gastric cancer patient
Externí odkaz:
https://doaj.org/article/feda28708e55413b8c88aba0b5a94854
Autor:
Chen-Chen Zhu, Han-Yuan Liu, Ying Wei, Zhen Shen, Li-Li Qian, Wei-Guo Song, Juan Wang, Da-Bao Wu, Xue-Fen Zhang, Ying Zhou
Publikováno v:
Taiwanese Journal of Obstetrics & Gynecology, Vol 58, Iss 3, Pp 332-337 (2019)
Objective: To evaluate the efficacy and toxicity of VMP regimen applied to the patients with low-risk gestational trophoblastic neoplasia (LR-GTN) treated in Anhui provincial hospital. Materials and methods: Between 2005 and 2017, 87 patients with lo
Externí odkaz:
https://doaj.org/article/8fa07ed605bb473abfaa5045b991f71a
Autor:
Tsung-Shine Ko, Han-Yuan Liu, Jiann Shieh, De Shieh, Szu-Hung Chen, Yen-Lun Chen, En-Ting Lin
Publikováno v:
Nanomaterials, Vol 11, Iss 3, p 733 (2021)
Two-dimensional layered material Molybdenum disulfide (MoS2) exhibits a flat surface without dangling bonds and is expected to be a suitable surface-enhanced Raman scattering (SERS) substrate for the detection of organic molecules. However, further f
Externí odkaz:
https://doaj.org/article/087c8ed221b946ffb98144313c0dcf8a
Autor:
Han-Yuan Liu, 劉瀚元
103
This study is aimed at three types of construction screws, #82.5, #102 and #124, to proceed the tests in accordance with CE authentication (EN 14592 timber structures). For yield moment test, 3-point bending test and 4-point bending
This study is aimed at three types of construction screws, #82.5, #102 and #124, to proceed the tests in accordance with CE authentication (EN 14592 timber structures). For yield moment test, 3-point bending test and 4-point bending
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/43003833486803654608
Autor:
Han-Yuan Liu, 劉瀚元
100
This experiment presents the research on optical modulation instability in the photorefractive nonlinear media. The material response time and the nonlinear strength are modulated by the intensity of light and the bias voltage. We discuss th
This experiment presents the research on optical modulation instability in the photorefractive nonlinear media. The material response time and the nonlinear strength are modulated by the intensity of light and the bias voltage. We discuss th
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/r3u837
Autor:
Samavi Farnush Bint E Naser, Arpita Roy, Anna-Maria Pappa, Alberto Salleo, Zachary A. Manzer, Zhongmou Chao, Hui Su, Han-Yuan Liu, Susan Daniel, Róisín M. Owens
Publikováno v:
ACS Applied Bio Materials. 4:7942-7950
Gangliosides, glycolipids that are abundant in the plasma membrane outer leaflet, play an integral role in cellular recognition, adhesion, and infection by interacting with different endogenous molecules, viruses, and toxins. Model membrane systems,
Autor:
Han-Yuan Liu, Priscilla L. Yang
Publikováno v:
Annu Rev Virol
Viral fusion glycoproteins catalyze membrane fusion during viral entry. Unlike most enzymes, however, they lack a conventional active site in which formation or scission of a specific covalent bond is catalyzed. Instead, they drive the membrane fusio