Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Han, Moshage"'
Autor:
Magnolia Martínez-Aguilar, María Camila Trillos-Almanza, Justina C. Wolters, Manon Buist-Homan, TransplantLines Investigators, Frederike van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 2, Pp 143-162 (2024)
Aim: Extracellular vesicles (EVs) have gained significant attention for their diagnostic and therapeutic potential in various diseases, including liver disorders. This study focuses on optimizing the isolation and characterization of small EVs from p
Externí odkaz:
https://doaj.org/article/fac795c2bb8b4781962d863728fd9087
Autor:
Maria Camila Trillos-Almanza, Magnolia Martinez-Aguilar, Johanna C. Arroyave-Ospina, Frederike van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Muscles, Vol 3, Iss 1, Pp 71-87 (2024)
This comprehensive review focuses on the dynamics of branched-chain amino acids (BCAAs) metabolism and its clinical implications in chronic liver disease, with emphasis on the emerging concept of muscle–liver crosstalk. BCAAs, indispensable for pro
Externí odkaz:
https://doaj.org/article/da692d15f16d4affae7549d8014fc3cb
Autor:
Zongmei Wu, Mengmeng Xia, Sandra Serna Salas, Maria Camila Trillos-Almanza, Magnolia Martinez Aguilar, Johanna C. Arroyave-Ospina, Junyu Wang, Marco Arrese, Svenja Sydor, Lars P. Bechmann, Frederike GI van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Exploration of Digestive Diseases, Vol 1, Iss 1, Pp 4-20 (2022)
The prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) is increasing rapidly worldwide due to the obesity epidemic. Advanced stages of the MAFLD, such as non-alcoholic steatohepatitis (NASH) with advanced fibrosis or cirrhosis
Externí odkaz:
https://doaj.org/article/ea74b7ba35244121ac69087233bb96a4
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1922 (2023)
Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-associated fatty liver disease (MAFLD). However, the mechanisms underlying their beneficial effects remain unclear. In the present study, we explored the potenti
Externí odkaz:
https://doaj.org/article/c1c5e77e792a40039ee733223c3ae9f1
Autor:
Maria Camila Trillos-Almanza, Hanna Wessel, Magnolia Martínez-Aguilar, Eline H. van den Berg, Rianne M. Douwes, Han Moshage, Margery A. Connelly, Stephan J. L. Bakker, Vincent E. de Meijer, Robin P. F. Dullaart, Hans Blokzijl
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 824 (2023)
Decreased circulating branched chain amino acids (BCAA) represent a prominent change in amino acid profiles in patients with end-stage liver disease (ESLD). These alterations are considered to contribute to sarcopenia and hepatic encephalopathy and m
Externí odkaz:
https://doaj.org/article/52adda2308304a418651fd6ac5bacbda
Autor:
Gloria Stephanie Villa-Jaimes, Fabio Alejandro Aguilar-Mora, Herson Antonio González-Ponce, Francisco Javier Avelar-González, Ma. Consolación Martínez Saldaña, Manon Buist-Homan, Han Moshage
Publikováno v:
Journal of Functional Foods, Vol 89, Iss , Pp 104960- (2022)
This study aimed to investigate whether Opuntia spp-extracts protect against diclofenac (DF)-induced hepatotoxicity. Rats were pretreated with Opuntia extracts, betanin (Bet) and N-acetylcysteine (NAC) followed by a single challenge of diclofenac. Li
Externí odkaz:
https://doaj.org/article/de307c2eef314934baec1ed128c31a56
Autor:
Gloria Stephanie Villa-Jaimes, Han Moshage, Francisco Javier Avelar-González, Herson Antonio González-Ponce, Manon Buist-Homan, Fidel Guevara-Lara, Esperanza Sánchez-Alemán, Sandra Luz Martínez-Hernández, Javier Ventura-Juárez, Martín Humberto Muñoz-Ortega, Ma. Consolación Martínez-Saldaña
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 113 (2023)
A molecular characterization of the main phytochemicals and antioxidant activity of Opuntia robusta (OR) fruit extract was carried out, as well as an evaluation of its hepatoprotective effect against diclofenac (DF)-induced acute liver injury was eva
Externí odkaz:
https://doaj.org/article/7165c3f6cfa24eed8de24ad1ad6073ef
Autor:
Nayeli Amalinalli Pulido-Hornedo, Javier Ventura-Juárez, Fidel Guevara-Lara, Herson Antonio González-Ponce, Esperanza Sánchez-Alemán, Manon Buist-Homan, Han Moshage, Ma. Consolación Martínez-Saldaña
Publikováno v:
Plants, Vol 11, Iss 15, p 2039 (2022)
Liver fibrosis is a chronic disease associated with oxidative stress that has a great impact on the population mortality. Due to their antioxidant capacity, we evaluated the protective effect of Opuntia robusta fruit (Or) on liver fibrosis. A nutrace
Externí odkaz:
https://doaj.org/article/8454f0da17a44d06847434e36132eab5
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 975 (2022)
Non-alcoholic fatty liver disease is characterized by disturbed lipid metabolism and increased oxidative stress. These conditions lead to the activation of different cellular response mechanisms, including senescence. Cellular senescence constitutes
Externí odkaz:
https://doaj.org/article/b6c376ff4176480f9b73043e1b9e1620
Autor:
W. Alfredo Ríos-Ocampo, Toos Daemen, Manon Buist-Homan, Klaas Nico Faber, María-Cristina Navas, Han Moshage
Publikováno v:
Redox Report, Vol 24, Iss 1, Pp 17-26 (2019)
Objectives: The occurrence of oxidative stress and endoplasmic reticulum (ER) stress in hepatitis C virus (HCV) infection has been demonstrated and play an important role in liver injury. During viral infection, hepatocytes must handle not only the r
Externí odkaz:
https://doaj.org/article/5bb5d5c796404136bec2ee774b35321e