Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Hamzeh Karimkhanloo"'
Autor:
Hamzeh Karimkhanloo, Stacey N. Keenan, Jacqueline Bayliss, William De Nardo, Paula M. Miotto, Camille J. Devereux, Shuai Nie, Nicholas A. Williamson, Andrew Ryan, Matthew J. Watt, Magdalene K. Montgomery
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Non-alcoholic steatohepatitis (NASH), characterized as the joint presence of steatosis, hepatocellular ballooning and lobular inflammation, and liver fibrosis are strong contributors to liver-related and overall mortality. Despite the high g
Externí odkaz:
https://doaj.org/article/0f81f952cf38469ca8daa7ce5886971f
Autor:
Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William De Nardo, Stacey N. Keenan, Paula M. Miotto, Hamzeh Karimkhanloo, Cheng Huang, Ralf B. Schittenhelm, Anthony S. Don, Andrew Ryan, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Benjamin L. Parker, Matthew J. Watt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Non-alcoholic steatohepatitis (NASH) and type 2 diabetes are closely linked, but the connecting pathophysiological mechanisms are incompletely understood. Here the authors identify arylsulfatase A as a NASH-induced hepatokine that inhibits hepatic ly
Externí odkaz:
https://doaj.org/article/0e3d36630f204b8aa3e526d0e0913eb1
Autor:
Mriga Dutt, Yaan-Kit Ng, Jeffrey Molendijk, Hamzeh Karimkhanloo, Luoping Liao, Ronnie Blazev, Magdalene K. Montgomery, Matthew J. Watt, Benjamin L. Parker
Publikováno v:
Proteomes, Vol 9, Iss 2, p 22 (2021)
The tongue is a heavily innervated and vascularized striated muscle that plays an important role in vocalization, swallowing and digestion. The surface of the tongue is lined with papillae which contain gustatory cells expressing various taste recept
Externí odkaz:
https://doaj.org/article/7877640ba01d46f4b794e3c80d99108b
Publikováno v:
Tumor Biology, Vol 39 (2017)
Hepatocellular carcinoma is the major form of primary liver cancer, which is the second and sixth leading cause of cancer-related death in men and women, respectively. Extensive research indicates that Wnt/β-catenin signaling pathway, which plays a
Externí odkaz:
https://doaj.org/article/3ede355875a846b3a6ae1fd03c735dc0
Autor:
Magdalene K. Montgomery, Stacey N Keenan, David A Wattchow, Damien J. Keating, Emily W. Sun, Matthew J. Watt, Hamzeh Karimkhanloo
Publikováno v:
Journal of Endocrinology. 248:167-179
Cathepsin S (CTSS) is a cysteine protease that regulates many physiological processes and is increased in obesity and type 2 diabetes. While previous studies show that deletion of CTSS improves glycaemic control through suppression of hepatic glucose
Autor:
Magdalene K. Montgomery, Benjamin L. Parker, Matthew J. Watt, Jeffrey Molendijk, Yaan-Kit Ng, Luoping Liao, Ronnie Blazev, Hamzeh Karimkhanloo, Mriga Dutt
Publikováno v:
Proteomes
Volume 9
Issue 2
Proteomes, Vol 9, Iss 22, p 22 (2021)
Volume 9
Issue 2
Proteomes, Vol 9, Iss 22, p 22 (2021)
The tongue is a heavily innervated and vascularized striated muscle that plays an important role in vocalization, swallowing and digestion. The surface of the tongue is lined with papillae which contain gustatory cells expressing various taste recept
Autor:
Magdalene K, Montgomery, Jacqueline, Bayliss, Shuai, Nie, William, De Nardo, Stacey N, Keenan, Paula M, Miotto, Hamzeh, Karimkhanloo, Cheng, Huang, Ralf B, Schittenhelm, Anthony S, Don, Andrew, Ryan, Nicholas A, Williamson, Geraldine J, Ooi, Wendy A, Brown, Paul R, Burton, Benjamin L, Parker, Matthew J, Watt
Publikováno v:
Nature communications. 13(1)
Non-alcoholic steatohepatitis (NASH) and type 2 diabetes are closely linked, yet the pathophysiological mechanisms underpinning this bidirectional relationship remain unresolved. Using proteomic approaches, we interrogate hepatocyte protein secretion
Publikováno v:
Molecular biology reports. 47(10)
MicroRNAs (miRNAs) are important gene regulators whose dysregulations can be involved in tumorigenesis. β-catenin, the main agent in the Wnt/β-catenin pathway, controls various genes and its over-expression has been discovered in different kinds of
Publikováno v:
Tumor Biology, Vol 39 (2017)
Hepatocellular carcinoma is the major form of primary liver cancer, which is the second and sixth leading cause of cancer-related death in men and women, respectively. Extensive research indicates that Wnt/β-catenin signaling pathway, which plays a
Autor:
Zeinab Ahsani, Samira Mohammadi-Yeganeh, Nosratollah Zarghami, Mahdi Paryan, Vahid Kia, Hamzeh Karimkhanloo
Publikováno v:
Applied biochemistry and biotechnology. 181(3)
Hepatocellular carcinoma (HCC) is an invasive form of hepatic cancer arising from the accumulation of multiple genetic alterations. In this study, the causal role of disturbed canonical Wnt/β-catenin pathway was approved, and some of HCC-driven impo