Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Hamzah SYED"'
Autor:
Buse Cevatemre, Ipek Bulut, Beyza Dedeoglu, Arda Isiklar, Hamzah Syed, Ozlem Yedier Bayram, Tugba Bagci-Onder, Ceyda Acilan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-14 (2024)
Abstract The development of taxane resistance remains a major challenge for castration resistant prostate cancer (CR-PCa), despite the effectiveness of taxanes in prolonging patient survival. To uncover novel targets, we performed an epigenetic drug
Externí odkaz:
https://doaj.org/article/dd8cef92c4f14c5aa97c75db52b7fb0a
Publikováno v:
Journal of Big Data, Vol 10, Iss 1, Pp 1-28 (2023)
Abstract Machine learning (ML) methods for uncovering single nucleotide polymorphisms (SNPs) in genome-wide association study (GWAS) data that can be used to predict disease outcomes are becoming increasingly used in genetic research. Two issues with
Externí odkaz:
https://doaj.org/article/4b6d27f55b894c45b3ebdea0af8933f6
Autor:
Ezgi Ozyerli-Goknar, Ezgi Yagmur Kala, Ali Cenk Aksu, Ipek Bulut, Ahmet Cingöz, Sheikh Nizamuddin, Martin Biniossek, Fidan Seker-Polat, Tunc Morova, Can Aztekin, Sonia H. Y. Kung, Hamzah Syed, Nurcan Tuncbag, Mehmet Gönen, Martin Philpott, Adam P. Cribbs, Ceyda Acilan, Nathan A. Lack, Tamer T. Onder, H. T. Marc Timmers, Tugba Bagci-Onder
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Glioblastoma is the most common and aggressive primary brain tumor with extremely poor prognosis, highlighting an urgent need for developing novel treatment options. Identifying epigenetic vulnerabilities of cancer cells can provi
Externí odkaz:
https://doaj.org/article/c47591d07edf46c2af096d40cbb069fd
Autor:
Ozlem Yedier-Bayram, Bengul Gokbayrak, Alisan Kayabolen, Ali Cenk Aksu, Ayse Derya Cavga, Ahmet Cingöz, Ezgi Yagmur Kala, Goktug Karabiyik, Rauf Günsay, Beril Esin, Tunc Morova, Fırat Uyulur, Hamzah Syed, Martin Philpott, Adam P. Cribbs, Sonia H. Y. Kung, Nathan A. Lack, Tamer T. Onder, Tugba Bagci-Onder
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-11 (2022)
Abstract Dysregulation of the epigenome due to alterations in chromatin modifier proteins commonly contribute to malignant transformation. To interrogate the roles of epigenetic modifiers in cancer cells, we generated an epigenome-wide CRISPR-Cas9 kn
Externí odkaz:
https://doaj.org/article/349d20f5c38141bd95e9a7af2609f50f
Publikováno v:
Micromachines, Vol 12, Iss 8, p 882 (2021)
Civil wars produce immense humanitarian crises, causing millions of individuals to seek refuge in other countries. The rate of disease prevalence has inclined among the refugees, increasing the cost of healthcare. Complex medical conditions and high
Externí odkaz:
https://doaj.org/article/02d019e1c2524b59ac0e28d4b00cf8ea
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-6 (2017)
Abstract Background Analysis of genome-wide association studies (GWAS) with “time to event” outcomes have become increasingly popular, predominantly in the context of pharmacogenetics, where the survival endpoint could be death, disease remission
Externí odkaz:
https://doaj.org/article/ed3c3b5985d2449c873c3f247bc4a07e
Publikováno v:
SOUTHERN JOURNAL OF SCIENCES. 30:32-46
Background: Coronavirus Disease-2019 (COVID-19) appears in individuals asymptomatically and in various symptomatic forms. Symptomatic diversity can result in diagnosis failures, hospitalization, admission to intensive care, multi-organ failure, and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98936985b7ef1d9b674299151e8728db
https://doi.org/10.48141/sjs.v30.n34.2022.04_atceken_pgs_32_46.pdf
https://doi.org/10.48141/sjs.v30.n34.2022.04_atceken_pgs_32_46.pdf
Akademický článek
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Autor:
Ezgi Ozyerli-Goknar, Ezgi Yagmur Kala, Ali Cenk Aksu, Ipek Bulut, Ahmet Cingöz, Sheikh Nizamuddin, Martin Biniossek, Fidan Seker-Polat, Tunc Morova, Can Aztekin, Sonia H.A. Kung, Hamzah Syed, Nurcan Tuncbag, Mehmet Gonen, Martin Philpott, Adam P. Cribbs, Ceyda Acilan, Nathan A. Lack, Tamer T. Onder, H.T. Marc Timmers, Tugba Bagci-Onder
Glioblastoma is the most common and aggressive primary brain tumor with poor prognosis, highlighting an urgent need for novel treatment strategies. In this study, we investigated epigenetic regulators of glioblastoma cell survival through CRISPR/Cas9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f032a1c762f5114e54d2d4605bc4daef
https://doi.org/10.1101/2022.08.17.504245
https://doi.org/10.1101/2022.08.17.504245
SummaryRare variants have been proposed as contributing to the “missing heritability” of complex human traits. There has been much recent development of methodology to investigate association of complex traits with multiple rare variants within p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e852deb297c34a7bb440d324aae3b7e
https://doi.org/10.1101/2021.12.19.473338
https://doi.org/10.1101/2021.12.19.473338