Zobrazeno 1 - 10 of 76 pro vyhledávání: '"Hamster polyomavirus"'
1
Vaccination with Prion Peptide-Displaying Polyomavirus-Like Particles Prolongs Incubation Time in Scrapie-Infected Mice
Autor: Martin H. Groschup, Rainer G. Ulrich, Martin Eiden, Alma Gedvilaite, Fabienne Leidel
Publikováno v: Viruses
Volume 13
Issue 5
Viruses, Vol 13, Iss 811, p 811 (2021)
Viruses, Basel : MDPI, 2021, vol. 13, iss. 5, art. no. 811, p. [1-14]
Prion diseases like scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle or Creutzfeldt–Jakob disease (CJD) in humans are fatal neurodegenerative diseases characterized by the conformational conversion of the normal, mainly α-helical
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0b7119c88eab4be735da0a4e4cb970
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2
Production and biomedical applications of virus-like particles derived from polyomaviruses
Autor: Markus de Raad, Enrico Mastrobattista, Erik A. Teunissen
Publikováno v: Journal of Controlled Release. 172:305-321
Virus-like particles (VLPs), aggregates of capsid proteins devoid of viral genetic material, show great promise in the fields of vaccine development and gene therapy. These particles spontaneously self-assemble after heterologous expression of viral
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb9ffec77ddaf2b28f640f4a49a8e28
https://doi.org/10.1016/j.jconrel.2013.08.026
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3
IgA antibody production by intrarectal immunization of mice using recombinant major capsid protein of hamster polyomavirus
Autor: Pamela Holzlöhner, D. Wagner, S. Hempel, Katja Heilmann, Katrin Messerschmidt, R. G. Ulrich
Publikováno v: European Journal of Microbiology and Immunology. 2:231-238
Viral proteins are highly antigenic and known as potent stimulators of adaptive immune responses. This mechanism is often used for biotechnological applications in monoclonal antibody production resulting in high-affinity IgG antibodies in most cases
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1789f6eadc72e3de02b5d53eb81bf2bf
https://doi.org/10.1556/eujmi.2.2012.3.9
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4
The Use of Recombinant Pseudotype Virus-Like Particles Harbouring Inserted Target Antigen to Generate Antibodies against Cellular Marker p16INK4A
Autor: Vaida Simanaviciene, Dovile Dekaminaviciute, Milda Norkiene, Indre Sezaite, Rita Lasickienė, Evelina Shikova, Alma Gedvilaite, Aurelija Zvirbliene
Publikováno v: The Scientific World Journal
The Scientific World Journal, Vol 2012 (2012)
Protein engineering provides an opportunity to generate new immunogens with desired features. Previously, we have demonstrated that hamster polyomavirus major capsid protein VP1-derived virus-like particles (VLPs) are highly immunogenic and can be em
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef02b9d22a7d83fd1eff5f15bafecff5
https://doi.org/10.1100/2012/263737
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5
Hamster polyomavirus-derived virus-like particles are able to transfer in vitro encapsidated plasmid DNA to mammalian cells
Autor: Siegfried Scherneck, Muhsin Özel, Rainer Ulrich, Paul Pumpens, Tatyana Voronkova, Velta Ose, Andris Kazaks
Publikováno v: Virus Genes. 34:303-314
The authentic major capsid protein 1 (VP1) of hamster polyomavirus (HaPyV) consists of 384 amino acid (aa) residues (42 kDa). Expression from an additional in-frame initiation codon located upstream from the authentic VP1 open reading frame (at posit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc95cb210bafd4a38493f1946c59ea3
https://doi.org/10.1007/s11262-006-0028-1
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6
Survey of molecular chaperone requirement for the biosynthesis of hamster polyomavirus VP1 protein in Saccharomyces cerevisiae
Autor: Alma Gedvilaite, Monika Valaviciute, Milda Norkiene, Karolis Goda, Rimantas Slibinskas
Publikováno v: Archives of virology. 161(7)
A number of viruses utilize molecular chaperones during various stages of their life cycle. It has been shown that members of the heat-shock protein 70 (Hsp70) chaperone family assist polyomavirus capsids during infection. However, the molecular chap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1f80c4841e084416d77211a80ac212
https://pubmed.ncbi.nlm.nih.gov/27038828
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7
Genome Sequences of a Rat Polyomavirus Related to Murine Polyomavirus, Rattus norvegicus Polyomavirus 1
Autor: Bernhard Ehlers, Rainer G. Ulrich, Dania Richter, Franz-Rainer Matuschka
Publikováno v: Genome Announcements
We amplified and sequenced six complete genomes of a polyomavirus from feral Norway rats ( Rattus norvegicus ) and from a long-term breeding colony derived from Norway rats. This virus, which is closely related to hamster polyomavirus and murine poly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719c344f1b88dc737c365525b0b6f2fa
http://europepmc.org/articles/PMC4559740
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8
Evaluation of Trichodysplasia Spinulosa-Associated Polyomavirus Capsid Protein as a New Carrier for Construction of Chimeric Virus-Like Particles Harboring Foreign Epitopes
Autor: Ausra Vaitiekaite, Rita Lasickiene, Danguole Ziogiene, Alma Gedvilaite, Indre Kucinskaite-Kodze, Aurelija Zvirbliene, Albertas Timinskas
Publikováno v: Viruses; Volume 7; Issue 8; Pages: 4204-4229
Viruses, Vol 7, Iss 8, Pp 4204-4229 (2015)
Viruses, Basel : MDPI AG, 2015, vol. 7, iss. 8, p. 4204-4229
Viruses
Volume 7
Issue 8
Pages 4204-4229
Recombinant virus-like particles (VLPs) represent a promising tool for protein engineering. Recently, trichodysplasia spinulosa-associated polyomavirus (TSPyV) viral protein 1 (VP1) was efficiently produced in yeast expression system and shown to sel
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9
Construction of polyomavirus-derived pseudotype virus-like particles displaying a functionally active neutralizing antibody against hepatitis B virus surface antigen
Autor: Corinna M. Bremer, Indre Kucinskaite-Kodze, Aurelija Zvirbliene, Milda Pleckaityte, Alma Gedvilaite, Dieter Glebe
Publikováno v: BMC Biotechnology, London : BioMed Central Ltd., 2015, vol. 15, art. no. 85, p. [1-9]
BMC Biotechnology
Background: Virus-like particles (VLPs) can be efficiently produced by heterologous expression of viral structural proteins in yeast. Due to their repetitive structure, VLPs are extensively used for protein engineering and generation of chimeric VLPs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b79b511392ce623012bf753c44a5f07
https://repository.vu.lt/VU:ELABAPDB13710673&prefLang=en_US
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10
Hamster polyomavirus
Autor: VERNEROVÁ, Tereza
Bachelor thesis is focused on viral disease Hamster Polyomavirus, occuring by syrian hamster (Mesocricetus auratus). It summarizes symptoms of the disease, methods of testing, cure possibilities, precautin and guidance for breeders.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2186::e3c17602ad664e9086205a8c6bbb33c0
http://www.nusl.cz/ntk/nusl-253130
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