Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated with the concept of pexotherapy

Autor: Ghzaiel, Imen, Zarrouk, Amira, Essadek, Soukaina, Martine, Lucy, Hammouda, Souha, Yammine, Aline, Ksila, Mohamed, Nury, Thomas, Meddeb, Wiem, Tahri Joutey, Mounia, Mihoubi, Wafa, Caccia, Claudio, Leoni, Valerio, Samadi, Mohammad, Acar, Niyazi, Andreoletti, Pierre, Hammami, Sonia, Ghrairi, Taoufik, Vejux, Anne, Hammami, Mohamed, Lizard, Gérard

Publikováno v: In Steroids July 2022 183

Antioxidant Properties and Cytoprotective Effect of Pistacia lentiscus L. Seed Oil against 7β-Hydroxycholesterol-Induced Toxicity in C2C12 Myoblasts: Reduction in Oxidative Stress, Mitochondrial and Peroxisomal Dysfunctions and Attenuation of Cell Death

Autor: Ghzaiel, Imen, Zarrouk, Amira, Nury, Thomas, Libergoli, Michela, Florio, Francesca, Hammouda, Souha, Ménétrier, Franck, Avoscan, Laure, Yammine, Aline, Samadi, Mohammad, Latruffe, Norbert, Biressi, Stefano, Levy, Débora, Bydlowski, Sérgio Paulo, Hammami, Sonia, Vejux, Anne, Hammami, Mohamed, Lizard, Gérard

Publikováno v: Antioxidants
Volume 10
Issue 11
Antioxidants, MDPI, 2021, 10 (11), pp.1772. ⟨10.3390/antiox10111772⟩
Antioxidants, 2021, 10 (11), pp.1772. ⟨10.3390/antiox10111772⟩

Aging is characterized by a progressive increase in oxidative stress, which favors lipid peroxidation and the formation of cholesterol oxide derivatives, including 7β-hydroxycholesterol (7β-OHC). This oxysterol, which is known to trigger oxidative

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