Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening.

Autor: Lalazar G; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York., Requena D; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Ramos-Espiritu L; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York., Ng D; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Bhola PD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., de Jong YP; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Wang R; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Narayan NJC; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York., Shebl B; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Levin S; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Michailidis E; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Kabbani M; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Vercauteren KOA; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.; Laboratory of Liver Infectious Diseases, Ghent University, Ghent, Belgium.; Institute of Tropical Medicine, Antwerp, Belgium., Hurley AM; Hospital Program Direction, The Rockefeller University, New York, New York., Farber BA; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Department of Surgery, Division of Pediatric Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa., Hammond WJ; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York., Saltsman JA 3rd; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, Mount Sinai Hospital, New York, New York., Weinberg EM; Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Glickman JF; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York., Lyons BA; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico., Ellison J; Division of Transplantation, Rush University Medical Center, Chicago, Illinois., Schadde E; Department of Surgery, Division of Transplantation and Division of Surgical Oncology, Rush University Medical Center, Chicago, Illinois., Hertl M; Division of Transplantation, Rush University Medical Center, Chicago, Illinois., Leiting JL; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Truty MJ; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Smoot RL; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Tierney F; Division of Abdominal Organ Transplantation, New York-Presbyterian/Columbia University, New York, New York., Kato T; Division of Abdominal Organ Transplantation, New York-Presbyterian/Columbia University, New York, New York., Wendel HG; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York., LaQuaglia MP; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Coffino P; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Torbenson MS; Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota., Ortiz MV; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Simon SM; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York. simon@rockefeller.edu.

Publikováno v: Cancer discovery [Cancer Discov] 2021 Oct; Vol. 11 (10), pp. 2544-2563. Date of Electronic Publication: 2021 Jun 14.

A Human Organoid Model of Aggressive Hepatoblastoma for Disease Modeling and Drug Testing.

Autor: Saltsman JA; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Hammond WJ; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Narayan NJC; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Requena D; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA., Gehart H; Hubrecht Institute, KNAW and University Medical Center Utrecht, 3584CT Utrecht, The Netherlands., Lalazar G; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA., LaQuaglia MP; Pediatric Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Clevers H; Hubrecht Institute, KNAW and University Medical Center Utrecht, 3584CT Utrecht, The Netherlands.; The Princess Maxima Center for Pediatric Oncology, 3584CT Utrecht, The Netherlands., Simon S; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Publikováno v: Cancers [Cancers (Basel)] 2020 Sep 18; Vol. 12 (9). Date of Electronic Publication: 2020 Sep 18.

Treatment and outcome of adult-onset neuroblastoma.

Autor: Suzuki M; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Kushner BH; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Kramer K; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Basu EM; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Roberts SS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Hammond WJ; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., LaQuaglia MP; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., Wolden SL; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Cheung NV; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY., Modak S; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.

Publikováno v: International journal of cancer [Int J Cancer] 2018 Sep 01; Vol. 143 (5), pp. 1249-1258. Date of Electronic Publication: 2018 Apr 06.

Urothelial neoplasms in pediatric and young adult patients: A large single-center series.

Autor: Saltsman JA; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., Malek MM; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., Reuter VE; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY., Hammond WJ; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., Danzer E; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., Herr HW; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY., LaQuaglia MP; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: laquaglm@mskcc.org.

Publikováno v: Journal of pediatric surgery [J Pediatr Surg] 2018 Feb; Vol. 53 (2), pp. 306-309. Date of Electronic Publication: 2017 Nov 14.

Thyroid neoplasms: incidental findings on extent of disease evaluation CT for other pediatric malignancies.

Autor: Hammond WJ; Pediatric Surgical Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Heaton TE; Pediatric Surgical Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: heatont@mskcc.org., Farber BA; Pediatric Surgical Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Mahmood UA; Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gluskin JS; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wolden SL; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., La Quaglia MP; Pediatric Surgical Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sklar CA; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Price AP; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Publikováno v: Journal of pediatric surgery [J Pediatr Surg] 2017 Jun; Vol. 52 (6), pp. 938-943. Date of Electronic Publication: 2017 Mar 15.