Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening.

Autor: Lalazar G; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York., Requena D; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Ramos-Espiritu L; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York., Ng D; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Bhola PD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., de Jong YP; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Wang R; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Narayan NJC; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York., Shebl B; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Levin S; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Michailidis E; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Kabbani M; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Vercauteren KOA; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.; Laboratory of Liver Infectious Diseases, Ghent University, Ghent, Belgium.; Institute of Tropical Medicine, Antwerp, Belgium., Hurley AM; Hospital Program Direction, The Rockefeller University, New York, New York., Farber BA; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Department of Surgery, Division of Pediatric Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa., Hammond WJ; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York., Saltsman JA 3rd; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, Mount Sinai Hospital, New York, New York., Weinberg EM; Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Glickman JF; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York., Lyons BA; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico., Ellison J; Division of Transplantation, Rush University Medical Center, Chicago, Illinois., Schadde E; Department of Surgery, Division of Transplantation and Division of Surgical Oncology, Rush University Medical Center, Chicago, Illinois., Hertl M; Division of Transplantation, Rush University Medical Center, Chicago, Illinois., Leiting JL; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Truty MJ; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Smoot RL; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Tierney F; Division of Abdominal Organ Transplantation, New York-Presbyterian/Columbia University, New York, New York., Kato T; Division of Abdominal Organ Transplantation, New York-Presbyterian/Columbia University, New York, New York., Wendel HG; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York., LaQuaglia MP; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Coffino P; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Torbenson MS; Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota., Ortiz MV; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Simon SM; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York. simon@rockefeller.edu.

Publikováno v: Cancer discovery [Cancer Discov] 2021 Oct; Vol. 11 (10), pp. 2544-2563. Date of Electronic Publication: 2021 Jun 14.

A Human Organoid Model of Aggressive Hepatoblastoma for Disease Modeling and Drug Testing.

Autor: Saltsman JA; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Hammond WJ; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Narayan NJC; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Requena D; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA., Gehart H; Hubrecht Institute, KNAW and University Medical Center Utrecht, 3584CT Utrecht, The Netherlands., Lalazar G; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA., LaQuaglia MP; Pediatric Surgery Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Clevers H; Hubrecht Institute, KNAW and University Medical Center Utrecht, 3584CT Utrecht, The Netherlands.; The Princess Maxima Center for Pediatric Oncology, 3584CT Utrecht, The Netherlands., Simon S; Laboratory of Cellular Biophysics, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.

Publikováno v: Cancers [Cancers (Basel)] 2020 Sep 18; Vol. 12 (9). Date of Electronic Publication: 2020 Sep 18.

Organoid as a promising tool for primary liver cancer research: a comprehensive review.

Autor: Hu, Xuekai¹ (AUTHOR), Wei, Jiayun^2,3 (AUTHOR), Liu, Pinyan^2,3 (AUTHOR), Zheng, Qiuxia² (AUTHOR), Zhang, Yue² (AUTHOR), Zhang, Qichen² (AUTHOR), Yao, Jia^2,3,4,5 (AUTHOR) yaoj06@lzu.edu.cn, Ni, Jingman^1,6,7 (AUTHOR) nijm@lzu.edu.cn

Publikováno v: Cell & Bioscience. 8/27/2024, Vol. 14 Issue 1, p1-23. 23p.

Intracranial metastasis in fibrolamellar hepatocellular carcinoma.

Autor: Hammond WJ; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York.; Laboratory of Cellular Biophysics, The Rockefeller University, New York City, New York., Lalazar G; Laboratory of Cellular Biophysics, The Rockefeller University, New York City, New York., Saltsman JA; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York.; Laboratory of Cellular Biophysics, The Rockefeller University, New York City, New York., Farber BA; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York.; Laboratory of Cellular Biophysics, The Rockefeller University, New York City, New York., Danzer E; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York., Sherpa TC; Laboratory of Cellular Biophysics, The Rockefeller University, New York City, New York., Banda CD; Laboratory of Cellular Biophysics, The Rockefeller University, New York City, New York., Andolina JR; Department of Pediatrics, Golisano Children's Hospital, University of Rochester Medical Center, Rochester, New York., Karimi S; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York City, New York., Brennan CW; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York City, New York.; Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York City, New York., Torbenson MS; Division of Anatomic Pathology, Department of Pathology, Mayo Clinic, Rochester, Minnesota., La Quaglia MP; Pediatric Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York., Simon SM; Laboratory of Cellular Biophysics, The Rockefeller University, New York City, New York.

Publikováno v: Pediatric blood & cancer [Pediatr Blood Cancer] 2018 Apr; Vol. 65 (4). Date of Electronic Publication: 2017 Dec 29.

Management of Ewing Family of Tumors Arising from Chest Wall in Children.

Autor: User, İdil Rana (AUTHOR), Ardıçlı, Burak (AUTHOR), Çiftçi, Arbay Özden (AUTHOR), Karnak, İbrahim (AUTHOR), Oğuz, Berna (AUTHOR), Haliloğlu, Mithat (AUTHOR), Kutluk, Tezer (AUTHOR), Yıldız, Ferah (AUTHOR), Orhan, Diclehan (AUTHOR), Üzümcügil, Filiz (AUTHOR), Ekinci, Saniye (AUTHOR)

Publikováno v: Journal of Pediatric Research. Jun2024, Vol. 11 Issue 2, p118-122. 5p.